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Aliases for OR51B5 Gene

Aliases for OR51B5 Gene

  • Olfactory Receptor, Family 51, Subfamily B, Member 5 2 3
  • Odorant Receptor HOR5beta5 3 4
  • Olfactory Receptor OR11-37 3 4
  • Olfactory Receptor 51B5 3
  • HOR5Beta5 3
  • OR11-37 3

External Ids for OR51B5 Gene

Previous GeneCards Identifiers for OR51B5 Gene

  • GC00U903062
  • GC11U900610
  • GC11M005321
  • GC11M005323

Summaries for OR51B5 Gene

Entrez Gene Summary for OR51B5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51B5 Gene

OR51B5 (Olfactory Receptor, Family 51, Subfamily B, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51E1.

UniProtKB/Swiss-Prot for OR51B5 Gene

  • Odorant receptor.

Gene Wiki entry for OR51B5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51B5 Gene

Genomics for OR51B5 Gene

Regulatory Elements for OR51B5 Gene

Genomic Location for OR51B5 Gene

5,340,883 bp from pter
5,346,910 bp from pter
6,028 bases
Minus strand

Genomic View for OR51B5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51B5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51B5 Gene

Proteins for OR51B5 Gene

  • Protein details for OR51B5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51B5
    Protein Accession:
    Secondary Accessions:
    • B2RN59

    Protein attributes for OR51B5 Gene

    312 amino acids
    Molecular mass:
    35241 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51B5 Gene

Proteomics data for OR51B5 Gene at MOPED

Post-translational modifications for OR51B5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR51B5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51B5 Gene

Domains for OR51B5 Gene

Gene Families for OR51B5 Gene

Protein Domains for OR51B5 Gene

Suggested Antigen Peptide Sequences for OR51B5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51B5: view

Function for OR51B5 Gene

Molecular function for OR51B5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51B5: view

Phenotypes for OR51B5 Gene

GenomeRNAi human phenotypes for OR51B5:
genes like me logo Genes that share phenotypes with OR51B5: view

Animal Model Products

CRISPR Products

miRNA for OR51B5 Gene

miRTarBase miRNAs that target OR51B5

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR51B5

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for OR51B5 Gene

Localization for OR51B5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51B5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR51B5 Gene COMPARTMENTS Subcellular localization image for OR51B5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51B5: view

Pathways for OR51B5 Gene

genes like me logo Genes that share pathways with OR51B5: view

Pathways by source for OR51B5 Gene

Interacting Proteins for OR51B5 Gene

Gene Ontology (GO) - Biological Process for OR51B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 11121057
genes like me logo Genes that share ontologies with OR51B5: view

Transcripts for OR51B5 Gene

mRNA/cDNA for OR51B5 Gene

(4) Additional mRNA sequences :
(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR51B5 Gene

Olfactory receptor, family 51, subfamily B, member 5:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR51B5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51B5 Gene

No ASD Table

Relevant External Links for OR51B5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51B5 Gene

mRNA expression in normal human tissues for OR51B5 Gene

mRNA differential expression in normal tissues according to GTEx for OR51B5 Gene

This gene is overexpressed in Ovary (4.8) and Testis (4.5).

SOURCE GeneReport for Unigene cluster for OR51B5 Gene Hs.690458

genes like me logo Genes that share expressions with OR51B5: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR51B5 Gene

Orthologs for OR51B5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR51B5 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC100684132 35
  • 72.02 (n)
  • 73.44 (a)
OR51B5 36
  • 84 (a)
(Pan troglodytes)
Mammalia LOC450980 35
  • 98.61 (n)
  • 96.47 (a)
OR51B5 36
  • 96 (a)
(Mus musculus)
Mammalia Olfr623 16
Olfr606 36
  • 49 (a)
(Bos Taurus)
Mammalia -- 36
  • 50 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 72 (a)
(Gallus gallus)
Aves -- 36
  • 46 (a)
Species with no ortholog for OR51B5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51B5 Gene

Gene Tree for OR51B5 (if available)
Gene Tree for OR51B5 (if available)

Paralogs for OR51B5 Gene

Paralogs for OR51B5 Gene

(430) SIMAP similar genes for OR51B5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR51B5: view

Variants for OR51B5 Gene

Sequence variations from dbSNP and Humsavar for OR51B5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
VAR_053307 -
VAR_053308 -
VAR_053309 -
VAR_053310 -
VAR_053311 -

Structural Variations from Database of Genomic Variants (DGV) for OR51B5 Gene

Variant ID Type Subtype PubMed ID
nsv524400 CNV Loss 19592680
nsv896931 CNV Loss 21882294
esv268103 CNV Insertion 20981092
esv26010 CNV Gain 19812545
dgv56n21 CNV Loss 19592680
nsv832057 CNV Loss 17160897
esv997323 CNV Gain 20482838
nsv896932 CNV Gain 21882294
nsv896933 CNV Gain 21882294
esv22160 CNV Loss 19812545
essv3627 CNV CNV 17122850
nsv896934 CNV Loss 21882294
dgv1025n71 CNV Loss 21882294
esv2664205 CNV Deletion 23128226
esv34391 CNV Loss 17911159
esv2744060 CNV Deletion 23290073
esv9420 CNV Loss 19470904
nsv521722 CNV Gain 19592680
nsv896938 CNV Gain 21882294
nsv467669 CNV Gain 19166990
nsv896939 CNV Loss 21882294
esv2660728 CNV Deletion 23128226
esv2744061 CNV Deletion 23290073
dgv195n67 CNV Loss 20364138
esv4563 CNV Deletion 18987735
esv2744062 CNV Deletion 23290073
esv2676206 CNV Deletion 23128226
nsv471745 CNV Loss 16327809
esv21699 CNV Loss 19812545
nsv442597 CNV CNV 18776908
nsv514621 CNV Loss 21397061
nsv510997 CNV Complex 20534489

Relevant External Links for OR51B5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51B5 Gene

Disorders for OR51B5 Gene

(1) University of Copenhagen DISEASES for OR51B5 Gene

Relevant External Links for OR51B5

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with OR51B5: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for OR51B5 Gene

Publications for OR51B5 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. (PMID: 20018918) Solovieff N. … Steinberg M.H. (Blood 2010) 3 48
  3. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. (PMID: 10220430) Bulger M. … Groudine M. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3

Products for OR51B5 Gene

Sources for OR51B5 Gene

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