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Aliases for OR51B2 Gene

Aliases for OR51B2 Gene

  • Olfactory Receptor, Family 51, Subfamily B, Member 2 (Gene/Pseudogene) 2 3
  • Odorant Receptor HOR5beta3 3 4
  • Olfactory Receptor 51B1 3 4
  • OR51B1P 3 4
  • Olfactory Receptor 51B2 3
  • HOR5Beta3 3

External Ids for OR51B2 Gene

Previous Symbols for OR51B2 Gene

  • OR51B1P

Summaries for OR51B2 Gene

Entrez Gene Summary for OR51B2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51B2 Gene

OR51B2 (Olfactory Receptor, Family 51, Subfamily B, Member 2 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR51B2 Gene

  • Odorant receptor.

Gene Wiki entry for OR51B2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51B2 Gene

Genomics for OR51B2 Gene

Genomic Location for OR51B2 Gene

Start:
5,323,298 bp from pter
End:
5,324,352 bp from pter
Size:
1,055 bases
Orientation:
Minus strand

Genomic View for OR51B2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51B2 Gene

Regulatory Elements for OR51B2 Gene

Proteins for OR51B2 Gene

  • Protein details for OR51B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y5P1-O51B2_HUMAN
    Recommended name:
    Olfactory receptor 51B2
    Protein Accession:
    Q9Y5P1
    Secondary Accessions:
    • Q96RD4

    Protein attributes for OR51B2 Gene

    Size:
    312 amino acids
    Molecular mass:
    35373 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51B2 Gene

Proteomics data for OR51B2 Gene at MOPED

Post-translational modifications for OR51B2 Gene

Other Protein References for OR51B2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51B2 Gene

Domains for OR51B2 Gene

Gene Families for OR51B2 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51B2 Gene

Suggested Antigen Peptide Sequences for OR51B2 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y5P1

UniProtKB/Swiss-Prot:

O51B2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9Y5P1
genes like me logo Genes that share domains with OR51B2: view

Function for OR51B2 Gene

Molecular function for OR51B2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51B2: view

Phenotypes for OR51B2 Gene

genes like me logo Genes that share phenotypes with OR51B2: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51B2 Gene

Localization for OR51B2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51B2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51B2 Gene COMPARTMENTS Subcellular localization image for OR51B2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51B2: view

Pathways for OR51B2 Gene

genes like me logo Genes that share pathways with OR51B2: view

Pathways by source for OR51B2 Gene

Interacting Proteins for OR51B2 Gene

Gene Ontology (GO) - Biological Process for OR51B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51B2: view

Transcripts for OR51B2 Gene

mRNA/cDNA for OR51B2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51B2 Gene

No ASD Table

Relevant External Links for OR51B2 Gene

GeneLoc Exon Structure for
OR51B2
ECgene alternative splicing isoforms for
OR51B2

Expression for OR51B2 Gene

mRNA expression in normal human tissues for OR51B2 Gene

SOURCE GeneReport for Unigene cluster for OR51B2 Gene Hs.680163

genes like me logo Genes that share expressions with OR51B2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR51B2 Gene

Orthologs for OR51B2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51B2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC745965 35
  • 99.04 (n)
  • 99.04 (a)
dog
(Canis familiaris)
Mammalia LOC485258 35
  • 77.45 (n)
  • 78.64 (a)
mouse
(Mus musculus)
Mammalia Olfr64 35
  • 75.6 (n)
  • 76.47 (a)
Olfr64 16
rat
(Rattus norvegicus)
Mammalia Olr131 35
  • 74.97 (n)
  • 75.74 (a)
Species with no ortholog for OR51B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51B2 Gene

ENSEMBL:
Gene Tree for OR51B2 (if available)
TreeFam:
Gene Tree for OR51B2 (if available)

Paralogs for OR51B2 Gene

Selected SIMAP similar genes for OR51B2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR51B2: view

No data available for Paralogs for OR51B2 Gene

Variants for OR51B2 Gene

Sequence variations from dbSNP and Humsavar for OR51B2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2723382 -- 5,326,220(-) ATCAA(C/T)GGCTT upstream-variant-2KB
rs3886224 -- 5,322,934(+) ATAAT(A/G)AAAAT downstream-variant-500B
rs4433594 -- 5,322,929(+) TGAGA(A/G)TAATG downstream-variant-500B
rs4910550 -- 5,324,630(+) GTTGT(C/T)TTCTT upstream-variant-2KB
rs4910750 -- 5,324,256(+) GGAAA(A/G)CCAGT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR51B2 Gene

Variant ID Type Subtype PubMed ID
nsv524400 CNV Loss 19592680
nsv819271 CNV Gain 19587683

Relevant External Links for OR51B2 Gene

HapMap Linkage Disequilibrium report
OR51B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51B2 Gene

Disorders for OR51B2 Gene

(1) University of Copenhagen DISEASES for OR51B2 Gene

genes like me logo Genes that share disorders with OR51B2: view

No data available for UniProtKB/Swiss-Prot for OR51B2 Gene

Publications for OR51B2 Gene

  1. Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. (PMID: 10220430) Bulger M. … Groudine M. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4
  5. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for OR51B2 Gene

  • antibodies-online proteins for OR51B2
  • antibodies-online antibodies for OR51B2
  • antibodies-online kits for OR51B2

Sources for OR51B2 Gene

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