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Aliases for OR51B2 Gene

Aliases for OR51B2 Gene

  • Olfactory Receptor Family 51 Subfamily B Member 2 (Gene/Pseudogene) 2 3 5
  • Odorant Receptor HOR5beta3 3 4
  • Olfactory Receptor 51B1 3 4
  • OR51B1P 3 4
  • Olfactory Receptor, Family 51, Subfamily B, Member 2 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 51, Subfamily B, Member 2 3
  • HOR5Beta3 3

External Ids for OR51B2 Gene

Previous HGNC Symbols for OR51B2 Gene

  • OR51B1P

Previous GeneCards Identifiers for OR51B2 Gene

  • GC11M006092
  • GC11M005646
  • GC11M005303
  • GC11M005308
  • GC11M005301

Summaries for OR51B2 Gene

Entrez Gene Summary for OR51B2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]

GeneCards Summary for OR51B2 Gene

OR51B2 (Olfactory Receptor Family 51 Subfamily B Member 2 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51E1.

UniProtKB/Swiss-Prot for OR51B2 Gene

  • Odorant receptor.

Gene Wiki entry for OR51B2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51B2 Gene

Genomics for OR51B2 Gene

Regulatory Elements for OR51B2 Gene

Enhancers for OR51B2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR51B2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR51B2 Gene

5,323,298 bp from pter
5,324,352 bp from pter
1,055 bases
Minus strand

Genomic View for OR51B2 Gene

Genes around OR51B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51B2 Gene

Proteins for OR51B2 Gene

  • Protein details for OR51B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51B2
    Protein Accession:
    Secondary Accessions:
    • Q96RD4

    Protein attributes for OR51B2 Gene

    312 amino acids
    Molecular mass:
    35373 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51B2 Gene

Proteomics data for OR51B2 Gene at MOPED

Post-translational modifications for OR51B2 Gene

  • Glycosylation at Asn 4
  • Modification sites at PhosphoSitePlus

Other Protein References for OR51B2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51B2 Gene

Domains & Families for OR51B2 Gene

Gene Families for OR51B2 Gene

Protein Domains for OR51B2 Gene

Suggested Antigen Peptide Sequences for OR51B2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51B2: view

Function for OR51B2 Gene

Molecular function for OR51B2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR51B2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51B2 Gene

Localization for OR51B2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51B2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR51B2 Gene COMPARTMENTS Subcellular localization image for OR51B2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51B2: view

Pathways & Interactions for OR51B2 Gene

genes like me logo Genes that share pathways with OR51B2: view

Pathways by source for OR51B2 Gene

Interacting Proteins for OR51B2 Gene

Gene Ontology (GO) - Biological Process for OR51B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51B2: view

No data available for SIGNOR curated interactions for OR51B2 Gene

Drugs & Compounds for OR51B2 Gene

No Compound Related Data Available

Transcripts for OR51B2 Gene

mRNA/cDNA for OR51B2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51B2 Gene

No ASD Table

Relevant External Links for OR51B2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51B2 Gene

mRNA expression in normal human tissues for OR51B2 Gene

SOURCE GeneReport for Unigene cluster for OR51B2 Gene Hs.680163

genes like me logo Genes that share expression patterns with OR51B2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR51B2 Gene

Orthologs for OR51B2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51B2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC485258 35
  • 77.45 (n)
  • 78.64 (a)
(Mus musculus)
Mammalia Olfr64 35
  • 75.6 (n)
  • 76.47 (a)
Olfr64 16
(Pan troglodytes)
Mammalia LOC745965 35
  • 99.04 (n)
  • 99.04 (a)
(Rattus norvegicus)
Mammalia Olr131 35
  • 74.97 (n)
  • 75.74 (a)
Species with no ortholog for OR51B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51B2 Gene

Gene Tree for OR51B2 (if available)
Gene Tree for OR51B2 (if available)

Paralogs for OR51B2 Gene

(417) SIMAP similar genes for OR51B2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR51B2: view

Variants for OR51B2 Gene

Sequence variations from dbSNP and Humsavar for OR51B2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs11036815 - 5,323,451(+) TAAAG(A/G)AGGAA reference, missense
rs7952293 - 5,323,940(+) GAAAC(A/G)ATCAT reference, missense
rs10837814 - 5,323,898(+) GGTGA(A/G)AATGG reference, missense
rs7937237 - 5,323,672(+) TCAGA(C/G)AGTCT reference, missense
rs11036814 - 5,323,362(+) GTTTA(A/C)CTACT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR51B2 Gene

Variant ID Type Subtype PubMed ID
nsv524400 CNV Loss 19592680
nsv819271 CNV Gain 19587683

Variation tolerance for OR51B2 Gene

Residual Variation Intolerance Score: 48.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.32; 96.30% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR51B2 Gene

Disorders for OR51B2 Gene

Relevant External Links for OR51B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR51B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51B2 Gene

Publications for OR51B2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 67
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3
  3. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for OR51B2 Gene

Sources for OR51B2 Gene