OR51A4 Gene

Aliases
for OR51A4 gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Previous GC identifers: GC11U990371 GC11M004932 GC11M004923

Summaries
for OR51A4 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for OR51A4 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000011.9  NC_018922.2  NT_009237.19  

Browse SwitchGear Promoter luciferase reporter plasmids

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR51A4

OR51A4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M004967:  view genomic region     (about GC identifiers)

Proteins
for OR51A4 gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for OR51A4: NX_Q8NGJ6

Post-translational modifications: 

OR51A4 Human Recombinant Protein Products:

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OR51A4 Antibody Products:

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	antibodies-online antibodies for OR51A4 (13 products)

OR51A4 Assay Products:

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	antibodies-online kits for OR51A4 (14 products)

Domains /
Families
for OR51A4 gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
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ProtoNet protein and cluster: Q8NGJ6

Find genes that share domains with OR51A4           About GenesLikeMe

Function
for OR51A4 gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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     Gene Ontology (GO): 2 molecular function terms:    About this table

genOway: Develop your customized and physiologically relevant rodent model for OR51A4

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		Search for qRT-PCR Assays for microRNAs that regulate OR51A4
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for OR51A4
		Predesigned siRNA for gene silencing in human, mouse, rat OR51A4

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for OR51A4

Clone Products:		OriGene clones in human, mouse for OR51A4 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OR51A4 (NM_001005329)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51A4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51A4

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for OR51A4
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51A4

Localization
for OR51A4 gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Subcellular locations from COMPARTMENTS: 

Compartment	Confidence
plasma membrane	5

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Gene Ontology (GO): 2 cellular component terms:    About this table

Pathways & Interactions
for OR51A4 gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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SuperPaths for OR51A4 About     See pathways by source

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	SuperPath	Contained pathways About
1	Olfactory Signaling Pathway	Olfactory Signaling Pathway 0.82 Olfactory transduction 0.82
2	Signaling by GPCR	Signaling by GPCR 0.90 Signal Transduction 0.58 GPCR downstream signaling 0.90

1 Reactome Pathway for OR51A4

Olfactory Signaling Pathway

1 Kegg Pathway  (Kegg details for OR51A4)

Olfactory transduction

Gene Ontology (GO): 1 biological process term:    About this table

Drugs & Compounds
for OR51A4 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
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Transcripts
for OR51A4 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for OR51A4 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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Orthologs
for OR51A4 gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for OR51A4 gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
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Paralogs for OR51A4 gene

OR51L1²  OR51T1²  OR51F2²  OR51G2²  OR51I1²  OR51A7²  OR51G1²  OR51H1P²  

OR51A2²  OR51I2²  OR51F1²  

Selected SIMAP similar genes for OR51A4 using alignment to 2 protein entries:     O51A4_HUMAN (see all proteins) (see all similar genes):

OR51A2    OR51A7    OR51L1    OR51E2    OR51G1    OR51H1P

OR51Q1    OR51M1    OR51B5    OR51E1    OR51I2    OR51V1

OR51G2    OR52M1    OR51B6    OR51F2    OR51I1    OR52K3P

Find genes that share paralogs with OR51A4           About GenesLikeMe

Genomic Variants
for OR51A4 gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for OR51A4 (see all 159)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs79421781,2	C	--	4892829(+)	AATTAA/GGATAC	1	--	us2k1		0	--	--	--	--
rs79422811,2	C,F,A	--	4892837(+)	TACACA/GCATTT	1	--	us2k1		11		NA WA CSA EA	373
rs787814661,2	F	--	4892914(+)	TTTACA/GTCATT	1	--	us2k1		1		WA	118
rs79454561,2	C,F,A,H	--	4892984(+)	ATCTAT/CATCTT	1	--	us2k1		12		NS EA NA WA CSA	781
rs79424421,2	C,F,H	--	4893032(+)	CTACAA/GAGGGC	1	--	us2k1		5		NS EA CSA	418
rs1870242841,2		--	4893047(+)	AGGTCA/GATTGC	1	--	us2k1		0	--	--	--	--
rs1885132351,2		--	4893051(+)	CAATTA/GCTCAT	1	--	us2k1		0	--	--	--	--
rs1812857981,2		--	4893193(+)	CTCTTA/GTCTTG	1	--	us2k1		0	--	--	--	--
rs753542961,2		--	4893311(+)	ACACAC/TTTCTG	1	--	us2k1		1		WA	118
rs1852990931,2		--	4893317(+)	TTCTGG/TTTTTT	1	--	us2k1		0	--	--	--	--

HapMap Linkage Disequilibrium report for OR51A4 ( 4967392 - 4968330 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for OR51A4 (see all 22):    About this table    

Variant ID	Type	Subtype	PubMed ID
dgv187e199	CNV	Deletion	23128226
dgv35n16	CNV	Deletion	17901297
esv2744056	CNV	Deletion	23290073
esv2568479	CNV	Deletion	19546169
nsv471358	CNV	Duplication	19718026
nsv7653	CNV	Insertion	18451855
nsv443000	CNV	Loss	18674749
dgv10n50	CNV	Loss	21212237
nsv64	CNV	Loss	15895083
nsv7652	CNV	Loss	18451855

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing OR51A4

DNA2.0 Custom Variant and Variant Library Synthesis for OR51A4

Disorders / Diseases
for OR51A4 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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Publications
for OR51A4 gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

External Searches for OR51A4 gene

Genome Databases showing OR51A4 gene

Other Databases showing OR51A4 gene

Specialized Databases showing OR51A4 gene

Products
for OR51A4 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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