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Aliases for OR4Q3 Gene

Aliases for OR4Q3 Gene

  • Olfactory Receptor Family 4 Subfamily Q Member 3 2 3 5
  • Olfactory Receptor, Family 4, Subfamily Q, Member 3 2 3
  • Olfactory Receptor OR14-3 3 4
  • Olfactory Receptor 4Q4 3 4
  • C14orf13 3 4
  • OR4Q4 3 4
  • Olfactory Receptor, Family 4, Subfamily Q, Member 4 3
  • C14_5008 3
  • OR14-3 3
  • HSA6 3

External Ids for OR4Q3 Gene

Previous HGNC Symbols for OR4Q3 Gene

  • OR4Q4

Previous GeneCards Identifiers for OR4Q3 Gene

  • GC00U990949
  • GC14U900436
  • GC14P019285
  • GC14P020215

Summaries for OR4Q3 Gene

Entrez Gene Summary for OR4Q3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4Q3 Gene

OR4Q3 (Olfactory Receptor Family 4 Subfamily Q Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR4D9.

UniProtKB/Swiss-Prot for OR4Q3 Gene

  • Odorant receptor.

Gene Wiki entry for OR4Q3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4Q3 Gene

Genomics for OR4Q3 Gene

Regulatory Elements for OR4Q3 Gene

Enhancers for OR4Q3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR4Q3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR4Q3 Gene

19,747,428 bp from pter
19,748,369 bp from pter
942 bases
Plus strand

Genomic View for OR4Q3 Gene

Genes around OR4Q3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR4Q3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR4Q3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4Q3 Gene

Proteins for OR4Q3 Gene

  • Protein details for OR4Q3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 4Q3
    Protein Accession:
    Secondary Accessions:
    • Q6IEX4

    Protein attributes for OR4Q3 Gene

    313 amino acids
    Molecular mass:
    35491 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4Q3 Gene

Proteomics data for OR4Q3 Gene at MOPED

Post-translational modifications for OR4Q3 Gene

Other Protein References for OR4Q3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4Q3 Gene

Domains & Families for OR4Q3 Gene

Gene Families for OR4Q3 Gene

Protein Domains for OR4Q3 Gene

Suggested Antigen Peptide Sequences for OR4Q3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4Q3: view

Function for OR4Q3 Gene

Molecular function for OR4Q3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4Q3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with OR4Q3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR4Q3 Gene

Localization for OR4Q3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4Q3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR4Q3 Gene COMPARTMENTS Subcellular localization image for OR4Q3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4Q3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR4Q3: view

Pathways & Interactions for OR4Q3 Gene

genes like me logo Genes that share pathways with OR4Q3: view

Pathways by source for OR4Q3 Gene

Interacting Proteins for OR4Q3 Gene

Gene Ontology (GO) - Biological Process for OR4Q3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4Q3: view

No data available for SIGNOR curated interactions for OR4Q3 Gene

Drugs & Compounds for OR4Q3 Gene

No Compound Related Data Available

Transcripts for OR4Q3 Gene

mRNA/cDNA for OR4Q3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4Q3 Gene

No ASD Table

Relevant External Links for OR4Q3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR4Q3 Gene

mRNA expression in normal human tissues for OR4Q3 Gene

SOURCE GeneReport for Unigene cluster for OR4Q3 Gene Hs.553828

genes like me logo Genes that share expression patterns with OR4Q3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR4Q3 Gene

Orthologs for OR4Q3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR4Q3 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia OR16G03 35
  • 86.56 (n)
  • 87.54 (a)
-- 36
  • 73 (a)
OR16G03 36
  • 75 (a)
(Mus musculus)
Mammalia Olfr735 35
  • 82.02 (n)
  • 81.58 (a)
Olfr735 16
Olfr735 36
  • 70 (a)
(Bos Taurus)
Mammalia OR4Q3 36
  • 85 (a)
(Monodelphis domestica)
Mammalia OR4Q3 36
  • 70 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 48 (a)
-- 36
  • 57 (a)
Species with no ortholog for OR4Q3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4Q3 Gene

Gene Tree for OR4Q3 (if available)
Gene Tree for OR4Q3 (if available)

Paralogs for OR4Q3 Gene

(447) SIMAP similar genes for OR4Q3 Gene using alignment to 1 proteins: Pseudogenes for OR4Q3 Gene

genes like me logo Genes that share paralogs with OR4Q3: view

Variants for OR4Q3 Gene

Sequence variations from dbSNP and Humsavar for OR4Q3 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs17210864 - 19,747,830(+) ACCTT(A/G)CAGTC reference, missense
rs12896533 - 19,748,139(+) AGGTC(C/T)TCTCT reference, missense
rs4412904 -- 19,747,620(+) TTTTA(A/G)GTCAT reference, missense
rs4494468 -- 19,747,515(+) TCTTA(A/C)TATTT reference, missense
rs10498263 -- 19,747,289(+) TTACC(C/T)GATAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR4Q3 Gene

Variant ID Type Subtype PubMed ID
esv23873 CNV Gain+Loss 19812545
esv33527 CNV Gain+Loss 17666407
nsv819711 CNV Loss 19587683
nsv9117 CNV Gain+Loss 18304495
dgv45e180 CNV Loss 20482838
nsv901117 CNV Gain 21882294
dgv599e1 CNV Complex 17122850
nsv428292 CNV Gain+Loss 18775914
nsv433422 CNV Gain 18776910
dgv1811n71 CNV Gain 21882294
dgv1812n71 CNV Gain 21882294
dgv601e1 CNV Complex 17122850
dgv1814n71 CNV Gain 21882294
dgv1816n71 CNV Gain 21882294
dgv1819n71 CNV Gain 21882294
dgv6n31 CNV Duplication 19718026
dgv1823n71 CNV Gain 21882294
nsv901168 CNV Gain+Loss 21882294
dgv1824n71 CNV Gain 21882294
dgv24n68 CNV Gain 17160897
nsv901192 CNV Loss 21882294
nsv901198 CNV Loss 21882294
nsv901202 CNV Gain 21882294
nsv901215 CNV Gain 21882294
dgv1825n71 CNV Gain 21882294
dgv1826n71 CNV Gain 21882294
dgv602e1 CNV Complex 17122850
dgv603e1 CNV Complex 17122850
dgv1827n71 CNV Gain+Loss 21882294
dgv1828n71 CNV Gain 21882294
dgv1829n71 CNV Gain 21882294
dgv1830n71 CNV Gain 21882294
dgv1831n71 CNV Gain+Loss 21882294
dgv1832n71 CNV Gain 21882294
dgv1833n71 CNV Loss 21882294
dgv1834n71 CNV Gain 21882294
nsv901268 CNV Loss 21882294
dgv1835n71 CNV Gain 21882294
nsv901299 CNV Gain 21882294
nsv511546 CNV Gain 21212237
esv1002355 CNV Loss 20482838
dgv1836n71 CNV Gain 21882294
nsv821676 CNV Gain 15273396
nsv826860 CNV Gain 20364138
dgv361n67 CNV Gain 20364138
nsv442679 CNV CNV 18776908
esv2421752 OTHER Complex 20811451
nsv514728 CNV Gain 21397061
nsv433273 CNV Loss 18776910
dgv79e55 CNV Loss 17911159
dgv80e55 CNV Gain 17911159
dgv81e55 CNV Gain 17911159
esv2751268 CNV Gain 17911159
dgv1837n71 CNV Gain 21882294
dgv1838n71 CNV Gain 21882294
nsv901336 CNV Gain 21882294
nsv901337 CNV Loss 21882294
dgv1839n71 CNV Gain 21882294

Variation tolerance for OR4Q3 Gene

Residual Variation Intolerance Score: 96.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.81; 66.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR4Q3 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4Q3 Gene

Disorders for OR4Q3 Gene

Relevant External Links for OR4Q3

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR4Q3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR4Q3 Gene

Publications for OR4Q3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. (PMID: 10706615) Rouquier S. … Giorgi D. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for OR4Q3 Gene

Sources for OR4Q3 Gene