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Aliases for OR4Q2 Gene

Aliases for OR4Q2 Gene

  • Olfactory Receptor, Family 4, Subfamily Q, Member 2 (Gene/Pseudogene) 2 3
  • Olfactory Receptor, Family 4, Subfamily Q, Member 2 Pseudogene 2 3
  • OR4Q2P 3 4
  • Olfactory Receptor OR14-21 4
  • Olfactory Receptor 4Q2 3

External Ids for OR4Q2 Gene

Previous HGNC Symbols for OR4Q2 Gene

  • OR4Q2P

Previous GeneCards Identifiers for OR4Q2 Gene

  • GC14P019541
  • GC14P020470
  • GC14P000596

Summaries for OR4Q2 Gene

Entrez Gene Summary for OR4Q2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4Q2 Gene

OR4Q2 (Olfactory Receptor, Family 4, Subfamily Q, Member 2 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4D9.

UniProtKB/Swiss-Prot for OR4Q2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4Q2 Gene

Genomics for OR4Q2 Gene

Genomic Location for OR4Q2 Gene

Start:
20,002,162 bp from pter
End:
20,003,163 bp from pter
Size:
1,002 bases
Orientation:
Plus strand

Genomic View for OR4Q2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4Q2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4Q2 Gene

No data available for Regulatory Elements for OR4Q2 Gene

Proteins for OR4Q2 Gene

  • Protein details for OR4Q2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C623-OR4Q2_HUMAN
    Recommended name:
    Olfactory receptor 4Q2
    Protein Accession:
    P0C623
    Secondary Accessions:

    Protein attributes for OR4Q2 Gene

    Size:
    313 amino acids
    Molecular mass:
    35487 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4Q2 Gene

Proteomics data for OR4Q2 Gene at MOPED

Post-translational modifications for OR4Q2 Gene

Other Protein References for OR4Q2 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for OR4Q2 Gene

Domains for OR4Q2 Gene

Gene Families for OR4Q2 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4Q2 Gene

Suggested Antigen Peptide Sequences for OR4Q2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C623

UniProtKB/Swiss-Prot:

OR4Q2_HUMAN :
  • P0C623
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4Q2: view

Function for OR4Q2 Gene

Molecular function for OR4Q2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4Q2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4Q2 Gene

Localization for OR4Q2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4Q2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4Q2 Gene COMPARTMENTS Subcellular localization image for OR4Q2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR4Q2: view

Pathways for OR4Q2 Gene

genes like me logo Genes that share pathways with OR4Q2: view

Pathways by source for OR4Q2 Gene

Interacting Proteins for OR4Q2 Gene

Gene Ontology (GO) - Biological Process for OR4Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4Q2: view

Transcripts for OR4Q2 Gene

mRNA/cDNA for OR4Q2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4Q2 Gene

No ASD Table

Relevant External Links for OR4Q2 Gene

GeneLoc Exon Structure for
OR4Q2
ECgene alternative splicing isoforms for
OR4Q2

Expression for OR4Q2 Gene

mRNA expression in normal human tissues for OR4Q2 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR4Q2 Gene

genes like me logo Genes that share expressions with OR4Q2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR4Q2 Gene

Orthologs for OR4Q2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4Q2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR4Q2 36
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 35 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr1507 36
  • 37 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia OR4Q2 36
  • 51 (a)
OneToOne
Species with no ortholog for OR4Q2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4Q2 Gene

ENSEMBL:
Gene Tree for OR4Q2 (if available)
TreeFam:
Gene Tree for OR4Q2 (if available)

Paralogs for OR4Q2 Gene

Selected SIMAP similar genes for OR4Q2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR4Q2 Gene

genes like me logo Genes that share paralogs with OR4Q2: view

Variants for OR4Q2 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR4Q2 Gene

P0C623-OR4Q2_HUMAN
A single nucleotide insertion at position Cys-180 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene

Relevant External Links for OR4Q2 Gene

HapMap Linkage Disequilibrium report
OR4Q2

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR4Q2 Gene

Disorders for OR4Q2 Gene

No disorders were found for OR4Q2 Gene.

No data available for UniProtKB/Swiss-Prot for OR4Q2 Gene

Publications for OR4Q2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR4Q2 Gene

Sources for OR4Q2 Gene

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