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Aliases for OR4N5 Gene

Aliases for OR4N5 Gene

  • Olfactory Receptor, Family 4, Subfamily N, Member 5 2 3
  • Olfactory Receptor OR14-33 4

External Ids for OR4N5 Gene

Summaries for OR4N5 Gene

Entrez Gene Summary for OR4N5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4N5 Gene

OR4N5 (Olfactory Receptor, Family 4, Subfamily N, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4D9.

UniProtKB/Swiss-Prot for OR4N5 Gene

  • Odorant receptor.

Gene Wiki entry for OR4N5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4N5 Gene

Genomics for OR4N5 Gene

Genomic Location for OR4N5 Gene

Start:
20,143,736 bp from pter
End:
20,144,662 bp from pter
Size:
927 bases
Orientation:
Plus strand

Genomic View for OR4N5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4N5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4N5 Gene

Regulatory Elements for OR4N5 Gene

Proteins for OR4N5 Gene

  • Protein details for OR4N5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXE1-OR4N5_HUMAN
    Recommended name:
    Olfactory receptor 4N5
    Protein Accession:
    Q8IXE1
    Secondary Accessions:
    • Q6IF11

    Protein attributes for OR4N5 Gene

    Size:
    308 amino acids
    Molecular mass:
    34696 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4N5 Gene

Proteomics data for OR4N5 Gene at MOPED

Post-translational modifications for OR4N5 Gene

Other Protein References for OR4N5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR4N5 Gene

Domains for OR4N5 Gene

Gene Families for OR4N5 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4N5 Gene

UniProtKB/Swiss-Prot:

OR4N5_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8IXE1
genes like me logo Genes that share domains with OR4N5: view

Function for OR4N5 Gene

Molecular function for OR4N5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4N5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4N5: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4N5 Gene

Localization for OR4N5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4N5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4N5 Gene COMPARTMENTS Subcellular localization image for OR4N5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4N5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4N5: view

Pathways for OR4N5 Gene

genes like me logo Genes that share pathways with OR4N5: view

Pathways by source for OR4N5 Gene

Interacting Proteins for OR4N5 Gene

Gene Ontology (GO) - Biological Process for OR4N5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4N5: view

Transcripts for OR4N5 Gene

mRNA/cDNA for OR4N5 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4N5 Gene

No ASD Table

Relevant External Links for OR4N5 Gene

GeneLoc Exon Structure for
OR4N5
ECgene alternative splicing isoforms for
OR4N5

Expression for OR4N5 Gene

mRNA expression in normal human tissues for OR4N5 Gene

SOURCE GeneReport for Unigene cluster for OR4N5 Gene Hs.553766

genes like me logo Genes that share expressions with OR4N5: view

Orthologs for OR4N5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR4N5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100614621 36
  • 99.13 (n)
  • 98.05 (a)
OR4N5 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR4N5 36
  • 86.8 (n)
  • 88.96 (a)
OR4N5 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC487467 36
  • 86.36 (n)
  • 88.96 (a)
OR4N5 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr722 36
  • 82.58 (n)
  • 86.36 (a)
Olfr722 16
Olfr722 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 79 (a)
ManyToMany
-- 37
  • 80 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr1624 36
  • 81.6 (n)
  • 86.69 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 54 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 56 (a)
OneToMany
Species with no ortholog for OR4N5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4N5 Gene

ENSEMBL:
Gene Tree for OR4N5 (if available)
TreeFam:
Gene Tree for OR4N5 (if available)

Paralogs for OR4N5 Gene

Selected SIMAP similar genes for OR4N5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4N5: view

Variants for OR4N5 Gene

Sequence variations from dbSNP and Humsavar for OR4N5 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1952801 -- 20,143,530(+) GCTAC(A/C)TAAAA upstream-variant-2KB
rs1952802 -- 20,143,531(+) CTACC(G/T)AAAAA upstream-variant-2KB
rs1959339 -- 20,142,190(+) GTGCG(A/G)TCTCA upstream-variant-2KB
rs10131326 - 20,144,306(+) GCACC(A/G)ATACC reference, missense
rs10134272 -- 20,144,960(+) agcag(A/G)aagtg downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR4N5 Gene

Variant ID Type Subtype PubMed ID
nsv901299 CNV Gain 21882294
dgv81e55 CNV Gain 17911159
esv2751268 CNV Gain 17911159
nsv832738 CNV Loss 17160897
nsv901465 CNV Gain 21882294
nsv521393 CNV Loss 19592680
nsv832739 CNV Gain 17160897

Relevant External Links for OR4N5 Gene

HapMap Linkage Disequilibrium report
OR4N5

Disorders for OR4N5 Gene

No disorders were found for OR4N5 Gene.

No data available for UniProtKB/Swiss-Prot for OR4N5 Gene

Publications for OR4N5 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR4N5 Gene

Sources for OR4N5 Gene

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