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Aliases for OR4K13 Gene

Aliases for OR4K13 Gene

  • Olfactory Receptor, Family 4, Subfamily K, Member 13 2 3
  • Olfactory Receptor OR14-27 3 4
  • Olfactory Receptor 4K13 3
  • OR14-27 3

External Ids for OR4K13 Gene

Previous GeneCards Identifiers for OR4K13 Gene

  • GC14U990442
  • GC14M018493
  • GC14M019571
  • GC14M020502

Summaries for OR4K13 Gene

Entrez Gene Summary for OR4K13 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4K13 Gene

OR4K13 (Olfactory Receptor, Family 4, Subfamily K, Member 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4F4.

UniProtKB/Swiss-Prot for OR4K13 Gene

  • Odorant receptor.

Gene Wiki entry for OR4K13 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4K13 Gene

Genomics for OR4K13 Gene

Regulatory Elements for OR4K13 Gene

Genomic Location for OR4K13 Gene

Start:
20,033,844 bp from pter
End:
20,034,760 bp from pter
Size:
917 bases
Orientation:
Minus strand

Genomic View for OR4K13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4K13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4K13 Gene

Proteins for OR4K13 Gene

  • Protein details for OR4K13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH42-OR4KD_HUMAN
    Recommended name:
    Olfactory receptor 4K13
    Protein Accession:
    Q8NH42
    Secondary Accessions:
    • Q6IF13

    Protein attributes for OR4K13 Gene

    Size:
    304 amino acids
    Molecular mass:
    34261 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4K13 Gene

Proteomics data for OR4K13 Gene at MOPED

Post-translational modifications for OR4K13 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4K13 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4K13 Gene

Domains for OR4K13 Gene

Gene Families for OR4K13 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4K13 Gene

Suggested Antigen Peptide Sequences for OR4K13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH42

UniProtKB/Swiss-Prot:

OR4KD_HUMAN :
  • Q8NH42
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4K13: view

Function for OR4K13 Gene

Molecular function for OR4K13 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4K13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4K13: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR4K13

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4K13 Gene

Localization for OR4K13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4K13 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4K13 Gene COMPARTMENTS Subcellular localization image for OR4K13 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4K13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4K13: view

Pathways for OR4K13 Gene

genes like me logo Genes that share pathways with OR4K13: view

Pathways by source for OR4K13 Gene

Interacting Proteins for OR4K13 Gene

Gene Ontology (GO) - Biological Process for OR4K13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4K13: view

Transcripts for OR4K13 Gene

mRNA/cDNA for OR4K13 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR4K13

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR4K13 Gene

No ASD Table

Relevant External Links for OR4K13 Gene

GeneLoc Exon Structure for
OR4K13
ECgene alternative splicing isoforms for
OR4K13

Expression for OR4K13 Gene

mRNA expression in normal human tissues for OR4K13 Gene

SOURCE GeneReport for Unigene cluster for OR4K13 Gene Hs.553573

genes like me logo Genes that share expressions with OR4K13: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR4K13 Gene

Orthologs for OR4K13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR4K13 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR4K13 35
  • 84.44 (n)
  • 84.33 (a)
-- 36
  • 61 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC473313 35
  • 99.56 (n)
  • 98.68 (a)
OR4K13 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR4K13 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR4K13 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr731 36
  • 56 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 42 (a)
OneToMany
Species with no ortholog for OR4K13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4K13 Gene

ENSEMBL:
Gene Tree for OR4K13 (if available)
TreeFam:
Gene Tree for OR4K13 (if available)

Paralogs for OR4K13 Gene

Selected SIMAP similar genes for OR4K13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4K13: view

Variants for OR4K13 Gene

Sequence variations from dbSNP and Humsavar for OR4K13 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs2775236 -- 20,034,762(+) ATATC(A/G)TCAAC upstream-variant-2KB
rs2775261 -- 20,033,803(+) AGAGA(C/G)TGTCT downstream-variant-500B
rs5807021 -- 20,036,637(+) CTTTT(-/A/AA/T)AAAAA upstream-variant-2KB
rs10484223 -- 20,036,027(+) AGTTA(C/T)CTGCA upstream-variant-2KB
rs10484224 -- 20,036,276(+) TTATG(A/T)CTAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR4K13 Gene

Variant ID Type Subtype PubMed ID
dgv599e1 CNV Complex 17122850
nsv428292 CNV Gain+Loss 18775914
dgv601e1 CNV Complex 17122850
dgv603e1 CNV Complex 17122850
nsv901299 CNV Gain 21882294
dgv81e55 CNV Gain 17911159
esv2751268 CNV Gain 17911159
esv34243 CNV Loss 17911159
essv15197 CNV CNV 17122850
nsv832737 CNV Gain 17160897
nsv469855 CNV Loss 16826518
nsv832738 CNV Loss 17160897

Relevant External Links for OR4K13 Gene

HapMap Linkage Disequilibrium report
OR4K13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4K13 Gene

Disorders for OR4K13 Gene

Relevant External Links for OR4K13

Genetic Association Database (GAD)
OR4K13

No disorders were found for OR4K13 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR4K13 Gene

Publications for OR4K13 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR4K13 Gene

Sources for OR4K13 Gene

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