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Aliases for OR4F3 Gene

Aliases for OR4F3 Gene

  • Olfactory Receptor, Family 4, Subfamily F, Member 3 2 3
  • Olfactory Receptor OR1-1 4
  • OR4F3 OR4F16 OR4F29 4

External Ids for OR4F3 Gene

Summaries for OR4F3 Gene

Entrez Gene Summary for OR4F3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4F3 Gene

OR4F3 (Olfactory Receptor, Family 4, Subfamily F, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. An important paralog of this gene is OR4F4.

UniProtKB/Swiss-Prot for OR4F3 Gene

  • Odorant receptor.

Gene Wiki entry for OR4F3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4F3 Gene

Genomics for OR4F3 Gene

Genomic Location for OR4F3 Gene

Start:
181,367,268 bp from pter
End:
181,368,262 bp from pter
Size:
995 bases
Orientation:
Plus strand

Genomic View for OR4F3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4F3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4F3 Gene

Regulatory Elements for OR4F3 Gene

Proteins for OR4F3 Gene

  • Protein details for OR4F3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IEY1-OR4F3_HUMAN
    Recommended name:
    Olfactory receptor 4F3/4F16/4F29
    Protein Accession:
    Q6IEY1
    Secondary Accessions:
    • B2RPQ6

    Protein attributes for OR4F3 Gene

    Size:
    312 amino acids
    Molecular mass:
    35074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4F3 Gene

Proteomics data for OR4F3 Gene at MOPED

Post-translational modifications for OR4F3 Gene

Other Protein References for OR4F3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR4F3 Gene

Domains for OR4F3 Gene

Gene Families for OR4F3 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4F3 Gene

UniProtKB/Swiss-Prot:

OR4F3_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q6IEY1
genes like me logo Genes that share domains with OR4F3: view

Function for OR4F3 Gene

Molecular function for OR4F3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4F3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4F3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4F3 Gene

Localization for OR4F3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4F3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4F3 Gene COMPARTMENTS Subcellular localization image for OR4F3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4F3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4F3: view

Pathways for OR4F3 Gene

genes like me logo Genes that share pathways with OR4F3: view

Pathways by source for OR4F3 Gene

Interacting Proteins for OR4F3 Gene

Gene Ontology (GO) - Biological Process for OR4F3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4F3: view

Transcripts for OR4F3 Gene

mRNA/cDNA for OR4F3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4F3 Gene

No ASD Table

Relevant External Links for OR4F3 Gene

GeneLoc Exon Structure for
OR4F3
ECgene alternative splicing isoforms for
OR4F3

Expression for OR4F3 Gene

mRNA expression in normal human tissues for OR4F3 Gene

SOURCE GeneReport for Unigene cluster for OR4F3 Gene Hs.722724

genes like me logo Genes that share expressions with OR4F3: view

Orthologs for OR4F3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4F3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 97 (a)
OneToMany
LOC744286 36
  • 99.14 (n)
  • 97.75 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 90 (a)
ManyToMany
-- 37
  • 88 (a)
ManyToMany
-- 37
  • 87 (a)
ManyToMany
LOC788764 36
  • 77.16 (n)
  • 71.43 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 91 (a)
OneToMany
cOR4F25 36
  • 78.1 (n)
  • 73.08 (a)
mouse
(Mus musculus)
Mammalia Olfr1303 36
  • 82.37 (n)
  • 82.05 (a)
Olfr1308 37
  • 70 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 74 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr774 36
  • 82.48 (n)
  • 83.01 (a)
Species with no ortholog for OR4F3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4F3 Gene

ENSEMBL:
Gene Tree for OR4F3 (if available)
TreeFam:
Gene Tree for OR4F3 (if available)

Paralogs for OR4F3 Gene

Selected SIMAP similar genes for OR4F3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR4F3: view

Variants for OR4F3 Gene

Structural Variations from Database of Genomic Variants (DGV) for OR4F3 Gene

Variant ID Type Subtype PubMed ID
dgv2n71 CNV Gain 21882294
dgv3e1 CNV Complex 17122850
nsv870793 CNV Gain 21882294
dgv4e1 CNV Complex 17122850
nsv428223 CNV Gain+Loss 18775914
dgv5e1 CNV Complex 17122850
esv27883 CNV Gain+Loss 19812545
nsv829647 CNV Gain+Loss 17160897
nsv471518 CNV Duplication 19718026
dgv1n14 CNV Gain 18776910
nsv10050 CNV Gain+Loss 18304495
nsv514924 CNV Complex 21397061
dgv6e1 CNV Complex 17122850
esv21732 CNV Gain+Loss 19812545
nsv471522 CNV Duplication 19718026
nsv830758 CNV Loss 17160897
dgv1e24 CNV Loss 17666407
dgv2n14 CNV Gain 18776910
nsv871459 CNV Gain 21882294
nsv831869 CNV Gain+Loss 17160897
esv28275 CNV Gain+Loss 19812545
nsv10793 CNV Gain+Loss 18304495
nsv820415 CNV Deletion 20802225
nsv471442 CNV Duplication 19718026

Relevant External Links for OR4F3 Gene

HapMap Linkage Disequilibrium report
OR4F3

No data available for Sequence variations from dbSNP and Humsavar for OR4F3 Gene

Disorders for OR4F3 Gene

No disorders were found for OR4F3 Gene.

No data available for UniProtKB/Swiss-Prot for OR4F3 Gene

Publications for OR4F3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR4F3 Gene

Sources for OR4F3 Gene

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