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Aliases for OR4F17 Gene

Aliases for OR4F17 Gene

  • Olfactory Receptor, Family 4, Subfamily F, Member 17 2 3
  • Olfactory Receptor 4F11 3 4
  • Olfactory Receptor 4F18 3 4
  • Olfactory Receptor 4F19 3 4
  • OR4F11P 3 4
  • OR4F18 3 4
  • OR4F19 3 4
  • Olfactory Receptor, Family 4, Subfamily F, Member 11 Pseudogene 3
  • Olfactory Receptor, Family 4, Subfamily F, Member 19 3
  • Olfactory Receptor 4F17 3

External Ids for OR4F17 Gene

Previous Symbols for OR4F17 Gene

  • OR4F19
  • OR4F11P
  • OR4F18

Summaries for OR4F17 Gene

Entrez Gene Summary for OR4F17 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4F17 Gene

OR4F17 (Olfactory Receptor, Family 4, Subfamily F, Member 17) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4F4.

UniProtKB/Swiss-Prot for OR4F17 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4F17 Gene

Genomics for OR4F17 Gene

Genomic Location for OR4F17 Gene

Start:
107,152 bp from pter
End:
111,696 bp from pter
Size:
4,545 bases
Orientation:
Plus strand

Genomic View for OR4F17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4F17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4F17 Gene

Regulatory Elements for OR4F17 Gene

Proteins for OR4F17 Gene

  • Protein details for OR4F17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGA8-O4F17_HUMAN
    Recommended name:
    Olfactory receptor 4F17
    Protein Accession:
    Q8NGA8
    Secondary Accessions:
    • B2RNE8

    Protein attributes for OR4F17 Gene

    Size:
    305 amino acids
    Molecular mass:
    34212 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4F17 Gene

Proteomics data for OR4F17 Gene at MOPED

Post-translational modifications for OR4F17 Gene

No Post-translational modifications

Other Protein References for OR4F17 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR4F17 Gene

Domains for OR4F17 Gene

Gene Families for OR4F17 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4F17 Gene

Suggested Antigen Peptide Sequences for OR4F17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGA8

UniProtKB/Swiss-Prot:

O4F17_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGA8
genes like me logo Genes that share domains with OR4F17: view

Function for OR4F17 Gene

Molecular function for OR4F17 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4F17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4F17: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4F17 Gene

Localization for OR4F17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4F17 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4F17 Gene COMPARTMENTS Subcellular localization image for OR4F17 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4F17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4F17: view

Pathways for OR4F17 Gene

genes like me logo Genes that share pathways with OR4F17: view

Pathways by source for OR4F17 Gene

Interacting Proteins for OR4F17 Gene

Gene Ontology (GO) - Biological Process for OR4F17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4F17: view

Transcripts for OR4F17 Gene

mRNA/cDNA for OR4F17 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4F17 Gene

No ASD Table

Relevant External Links for OR4F17 Gene

GeneLoc Exon Structure for
OR4F17
ECgene alternative splicing isoforms for
OR4F17

Expression for OR4F17 Gene

mRNA expression in normal human tissues for OR4F17 Gene

SOURCE GeneReport for Unigene cluster for OR4F17 Gene Hs.572591

genes like me logo Genes that share expressions with OR4F17: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR4F17 Gene

Orthologs for OR4F17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4F17 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 81 (a)
OneToMany
LOC100608733 35
  • 99.45 (n)
  • 98.36 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 78 (a)
OneToMany
LOC785647 35
  • 88.34 (n)
  • 85.15 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 58 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr1289 36
  • 82 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 59 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 57 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr765 35
  • 83.39 (n)
  • 82.84 (a)
Species with no ortholog for OR4F17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4F17 Gene

ENSEMBL:
Gene Tree for OR4F17 (if available)
TreeFam:
Gene Tree for OR4F17 (if available)

Paralogs for OR4F17 Gene

Selected SIMAP similar genes for OR4F17 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR4F17: view

Variants for OR4F17 Gene

Sequence variations from dbSNP and Humsavar for OR4F17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1638359 -- 110,437(+) GAAGC(C/T)GAGAT upstream-variant-2KB, intron-variant
rs3855807 -- 108,239(-) TATTC(A/T)TGGAA intron-variant
rs8106297 -- 107,958(+) atatt(A/T)tatta intron-variant
rs8106302 -- 107,962(+) tttat(A/T)atata intron-variant
rs10543188 -- 107,954(+) ATATA(-/TATTT)TATTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR4F17 Gene

Variant ID Type Subtype PubMed ID
nsv9651 CNV Gain+Loss 18304495
nsv910070 CNV Gain 21882294
nsv471520 CNV Duplication 19718026
nsv820962 CNV Duplication 20802225
esv22059 CNV Gain+Loss 19812545
nsv471407 CNV Duplication 19718026

Relevant External Links for OR4F17 Gene

HapMap Linkage Disequilibrium report
OR4F17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4F17 Gene

Disorders for OR4F17 Gene

No disorders were found for OR4F17 Gene.

No data available for UniProtKB/Swiss-Prot for OR4F17 Gene

Publications for OR4F17 Gene

  1. Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. (PMID: 9384599) Trask B.J. … van den Engh G. (Hum. Mol. Genet. 1998) 3
  2. Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non- homologous chromosomes. (PMID: 11689483) Mefford H.C. … Trask B.J. (Hum. Mol. Genet. 2001) 3
  3. Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location. (PMID: 11689484) Linardopoulou E. … Trask B.J. (Hum. Mol. Genet. 2001) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for OR4F17 Gene

  • antibodies-online peptides for OR4F17
  • antibodies-online antibodies for OR4F17
  • antibodies-online kits for OR4F17

Sources for OR4F17 Gene

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