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Aliases for OR4F16 Gene

Aliases for OR4F16 Gene

  • Olfactory Receptor, Family 4, Subfamily F, Member 16 2 3
  • Olfactory Receptor OR1-1 3 4
  • Olfactory Receptor 4F3/4F16/4F29 3
  • Olfactory Receptor OR7-21 3
  • Olfactory Receptor OR4F16 3
  • OR4F3 OR4F16 OR4F29 4
  • OR7-21 3
  • OR1-1 3

External Ids for OR4F16 Gene

Previous GeneCards Identifiers for OR4F16 Gene

  • GC06U990266
  • GC08M000108
  • GC01M000662
  • GC01M000611
  • GC05P180727
  • GC01M000622

Summaries for OR4F16 Gene

Entrez Gene Summary for OR4F16 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4F16 Gene

OR4F16 (Olfactory Receptor, Family 4, Subfamily F, Member 16) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. An important paralog of this gene is OR4F29.

UniProtKB/Swiss-Prot for OR4F16 Gene

  • Odorant receptor.

Gene Wiki entry for OR4F16 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4F16 Gene

Genomics for OR4F16 Gene

Regulatory Elements for OR4F16 Gene

Genomic Location for OR4F16 Gene

Start:
685,716 bp from pter
End:
686,654 bp from pter
Size:
939 bases
Orientation:
Minus strand

Genomic View for OR4F16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4F16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4F16 Gene

Proteins for OR4F16 Gene

  • Protein details for OR4F16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IEY1-OR4F3_HUMAN
    Recommended name:
    Olfactory receptor 4F3/4F16/4F29
    Protein Accession:
    Q6IEY1
    Secondary Accessions:
    • B2RPQ6

    Protein attributes for OR4F16 Gene

    Size:
    312 amino acids
    Molecular mass:
    35074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4F16 Gene

Proteomics data for OR4F16 Gene at MOPED

Post-translational modifications for OR4F16 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4F16 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4F16 Gene

Domains for OR4F16 Gene

Gene Families for OR4F16 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4F16 Gene

Graphical View of Domain Structure for InterPro Entry

Q6IEY1

UniProtKB/Swiss-Prot:

OR4F3_HUMAN :
  • Q6IEY1
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4F16: view

No data available for Suggested Antigen Peptide Sequences for OR4F16 Gene

Function for OR4F16 Gene

Molecular function for OR4F16 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4F16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4F16: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4F16 Gene

Localization for OR4F16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4F16 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4F16 Gene COMPARTMENTS Subcellular localization image for OR4F16 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4F16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4F16: view

Pathways for OR4F16 Gene

genes like me logo Genes that share pathways with OR4F16: view

Pathways by source for OR4F16 Gene

Interacting Proteins for OR4F16 Gene

Gene Ontology (GO) - Biological Process for OR4F16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4F16: view

Transcripts for OR4F16 Gene

mRNA/cDNA for OR4F16 Gene

(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR4F16 Gene

Olfactory receptor, family 4, subfamily F, member 16:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR4F16

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR4F16
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR4F16 Gene

No ASD Table

Relevant External Links for OR4F16 Gene

GeneLoc Exon Structure for
OR4F16
ECgene alternative splicing isoforms for
OR4F16

Expression for OR4F16 Gene

mRNA expression in normal human tissues for OR4F16 Gene

SOURCE GeneReport for Unigene cluster for OR4F16 Gene Hs.632360

genes like me logo Genes that share expressions with OR4F16: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR4F16 Gene

Orthologs for OR4F16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4F16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC744286 35
  • 99.14 (n)
  • 97.75 (a)
cow
(Bos Taurus)
Mammalia LOC788764 35
  • 77.16 (n)
  • 71.43 (a)
dog
(Canis familiaris)
Mammalia cOR4F25 35
  • 78.1 (n)
  • 73.08 (a)
mouse
(Mus musculus)
Mammalia Olfr1303 35
  • 82.37 (n)
  • 82.05 (a)
Olfr1316 16
rat
(Rattus norvegicus)
Mammalia Olr774 35
  • 82.48 (n)
  • 83.01 (a)
Species with no ortholog for OR4F16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4F16 Gene

ENSEMBL:
Gene Tree for OR4F16 (if available)
TreeFam:
Gene Tree for OR4F16 (if available)

Paralogs for OR4F16 Gene

Paralogs for OR4F16 Gene

Selected SIMAP similar genes for OR4F16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4F16: view

Variants for OR4F16 Gene

Sequence variations from dbSNP and Humsavar for OR4F16 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs401814 -- 686,968(+) ACCTG(C/T)GATAT upstream-variant-2KB
rs61769316 -- 687,283(+) ATGCT(C/T)ACTGC upstream-variant-2KB
rs78359845 -- 685,692(+) TGTTT(A/G)ATGAG downstream-variant-500B
rs111891105 -- 687,127(-) CCAGG(C/T)ACCTC upstream-variant-2KB
rs201217585 -- 687,622(+) TTCCC(C/T)ACCCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR4F16 Gene

Variant ID Type Subtype PubMed ID
dgv2n71 CNV Gain 21882294
dgv3e1 CNV Complex 17122850
nsv870793 CNV Gain 21882294
dgv4e1 CNV Complex 17122850
nsv428223 CNV Gain+Loss 18775914
dgv5e1 CNV Complex 17122850
esv27883 CNV Gain+Loss 19812545
nsv829647 CNV Gain+Loss 17160897
nsv471518 CNV Duplication 19718026
dgv1n14 CNV Gain 18776910
nsv10050 CNV Gain+Loss 18304495
nsv514924 CNV Complex 21397061
dgv6e1 CNV Complex 17122850
esv21732 CNV Gain+Loss 19812545
nsv471522 CNV Duplication 19718026
nsv830758 CNV Loss 17160897
dgv1e24 CNV Loss 17666407
dgv2n14 CNV Gain 18776910
nsv871459 CNV Gain 21882294
nsv831869 CNV Gain+Loss 17160897
esv28275 CNV Gain+Loss 19812545
nsv10793 CNV Gain+Loss 18304495
nsv820415 CNV Deletion 20802225
nsv471442 CNV Duplication 19718026

Relevant External Links for OR4F16 Gene

HapMap Linkage Disequilibrium report
OR4F16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4F16 Gene

Disorders for OR4F16 Gene

No disorders were found for OR4F16 Gene.

No data available for UniProtKB/Swiss-Prot for OR4F16 Gene

Publications for OR4F16 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for OR4F16 Gene

Sources for OR4F16 Gene

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