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Aliases for OR4E1 Gene

Aliases for OR4E1 Gene

  • Olfactory Receptor, Family 4, Subfamily E, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor, Family 4, Subfamily E, Member 1 Pseudogene 2 3
  • OR4E1P 3 4
  • Olfactory Receptor OR14-43 4

External Ids for OR4E1 Gene

Previous HGNC Symbols for OR4E1 Gene

  • OR4E1P

Previous GeneCards Identifiers for OR4E1 Gene

  • GC14M021207
  • GC14M022139
  • GC14M022141

Summaries for OR4E1 Gene

Entrez Gene Summary for OR4E1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4E1 Gene

OR4E1 (Olfactory Receptor, Family 4, Subfamily E, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR4E1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4E1 Gene

Genomics for OR4E1 Gene

Genomic Location for OR4E1 Gene

Start:
21,669,891 bp from pter
End:
21,671,035 bp from pter
Size:
1,145 bases
Orientation:
Minus strand

Genomic View for OR4E1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4E1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4E1 Gene

No data available for Regulatory Elements for OR4E1 Gene

Proteins for OR4E1 Gene

  • Protein details for OR4E1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C645-OR4E1_HUMAN
    Recommended name:
    Olfactory receptor 4E1
    Protein Accession:
    P0C645
    Secondary Accessions:

    Protein attributes for OR4E1 Gene

    Size:
    316 amino acids
    Molecular mass:
    35862 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4E1 Gene

Proteomics data for OR4E1 Gene at MOPED

Post-translational modifications for OR4E1 Gene

Other Protein References for OR4E1 Gene

Reactome Protein details:

No data available for DME Specific Peptides for OR4E1 Gene

Domains for OR4E1 Gene

Gene Families for OR4E1 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4E1 Gene

Suggested Antigen Peptide Sequences for OR4E1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C645

UniProtKB/Swiss-Prot:

OR4E1_HUMAN :
  • P0C645
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4E1: view

Function for OR4E1 Gene

Molecular function for OR4E1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4E1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4E1 Gene

Localization for OR4E1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4E1 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR4E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR4E1: view

No data available for Subcellular locations from COMPARTMENTS for OR4E1 Gene

Pathways for OR4E1 Gene

genes like me logo Genes that share pathways with OR4E1: view

Pathways by source for OR4E1 Gene

Interacting Proteins for OR4E1 Gene

Gene Ontology (GO) - Biological Process for OR4E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4E1: view

Transcripts for OR4E1 Gene

mRNA/cDNA for OR4E1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4E1 Gene

No ASD Table

Relevant External Links for OR4E1 Gene

GeneLoc Exon Structure for
OR4E1
ECgene alternative splicing isoforms for
OR4E1

Expression for OR4E1 Gene

mRNA expression in normal human tissues for OR4E1 Gene

genes like me logo Genes that share expressions with OR4E1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR4E1 Gene

Orthologs for OR4E1 Gene

Evolution for OR4E1 Gene

ENSEMBL:
Gene Tree for OR4E1 (if available)
TreeFam:
Gene Tree for OR4E1 (if available)

No data available for Orthologs for OR4E1 Gene

Paralogs for OR4E1 Gene

Selected SIMAP similar genes for OR4E1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4E1: view

No data available for Paralogs for OR4E1 Gene

Variants for OR4E1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR4E1 Gene

P0C645-OR4E1_HUMAN
A double nucleotide deletion at position Pro-197 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene

Relevant External Links for OR4E1 Gene

HapMap Linkage Disequilibrium report
OR4E1

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR4E1 Gene

Disorders for OR4E1 Gene

No disorders were found for OR4E1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR4E1 Gene

Publications for OR4E1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. Genetic elucidation of human hyperosmia to isovaleric acid. (PMID: 17973576) Menashe I. … Lancet D. (PLoS Biol. 2007) 3 4
  4. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 3
  5. Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones. (PMID: 9110172) Boysen C. … Hood L. (Genome Res. 1997) 3

Products for OR4E1 Gene

Sources for OR4E1 Gene

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