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Aliases for OR4C5 Gene

Aliases for OR4C5 Gene

  • Olfactory Receptor, Family 4, Subfamily C, Member 5 (Gene/Pseudogene) 2 3
  • Olfactory Receptor, Family 4, Subfamily C, Member 5 Pseudogene 2 3
  • Olfactory Receptor, Family 4, Subfamily C, Member 5 2
  • Olfactory Receptor OR11-99 4
  • OR4C5Q 3
  • OR4C5P 3

External Ids for OR4C5 Gene

Previous Symbols for OR4C5 Gene

  • OR4C5P

Summaries for OR4C5 Gene

Entrez Gene Summary for OR4C5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4C5 Gene

OR4C5 (Olfactory Receptor, Family 4, Subfamily C, Member 5 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4C5 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4C5 Gene

Genomics for OR4C5 Gene

Genomic Location for OR4C5 Gene

Start:
48,365,397 bp from pter
End:
48,366,465 bp from pter
Size:
1,069 bases
Orientation:
Minus strand

Genomic View for OR4C5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4C5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4C5 Gene

No data available for Regulatory Elements for OR4C5 Gene

Proteins for OR4C5 Gene

  • Protein details for OR4C5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGB2-OR4C5_HUMAN
    Recommended name:
    Olfactory receptor 4C5
    Protein Accession:
    Q8NGB2
    Secondary Accessions:
    • Q6IFB2

    Protein attributes for OR4C5 Gene

    Size:
    326 amino acids
    Molecular mass:
    36862 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04748.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR4C5 Gene

Proteomics data for OR4C5 Gene at MOPED

Post-translational modifications for OR4C5 Gene

Other Protein References for OR4C5 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for OR4C5 Gene

Domains for OR4C5 Gene

Gene Families for OR4C5 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4C5 Gene

UniProtKB/Swiss-Prot:

OR4C5_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGB2
genes like me logo Genes that share domains with OR4C5: view

Function for OR4C5 Gene

Molecular function for OR4C5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4C5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4C5: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4C5 Gene

Localization for OR4C5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4C5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4C5 Gene COMPARTMENTS Subcellular localization image for OR4C5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4C5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4C5: view

Pathways for OR4C5 Gene

genes like me logo Genes that share pathways with OR4C5: view

Pathways by source for OR4C5 Gene

Interacting Proteins for OR4C5 Gene

Gene Ontology (GO) - Biological Process for OR4C5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4C5: view

Transcripts for OR4C5 Gene

mRNA/cDNA for OR4C5 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4C5 Gene

No ASD Table

Relevant External Links for OR4C5 Gene

GeneLoc Exon Structure for
OR4C5
ECgene alternative splicing isoforms for
OR4C5

Expression for OR4C5 Gene

mRNA expression in normal human tissues for OR4C5 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR4C5 Gene

genes like me logo Genes that share expressions with OR4C5: view

Orthologs for OR4C5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4C5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR4C5 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR4C5 37
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR12E07 37
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1260 16
Olfr1260 37
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 69 (a)
OneToMany
-- 37
  • 65 (a)
OneToMany
Species with no ortholog for OR4C5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4C5 Gene

ENSEMBL:
Gene Tree for OR4C5 (if available)
TreeFam:
Gene Tree for OR4C5 (if available)

Paralogs for OR4C5 Gene

Selected SIMAP similar genes for OR4C5 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR4C5 Gene

genes like me logo Genes that share paralogs with OR4C5: view

Variants for OR4C5 Gene

Relevant External Links for OR4C5 Gene

HapMap Linkage Disequilibrium report
OR4C5

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR4C5 Gene

Disorders for OR4C5 Gene

Relevant External Links for OR4C5

Genetic Association Database (GAD)
OR4C5
genes like me logo Genes that share disorders with OR4C5: view

No data available for UniProtKB/Swiss-Prot for OR4C5 Gene

Publications for OR4C5 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR4C5 Gene

Sources for OR4C5 Gene

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