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Aliases for OR4C15 Gene

Aliases for OR4C15 Gene

  • Olfactory Receptor, Family 4, Subfamily C, Member 15 2 3
  • Olfactory Receptor OR11-127 3 4
  • Olfactory Receptor OR11-134 3 4
  • Olfactory Receptor 4C15 3
  • OR11-127 3
  • OR11-134 3

External Ids for OR4C15 Gene

Summaries for OR4C15 Gene

Entrez Gene Summary for OR4C15 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4C15 Gene

OR4C15 (Olfactory Receptor, Family 4, Subfamily C, Member 15) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4C15 Gene

  • Odorant receptor.

Gene Wiki entry for OR4C15 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4C15 Gene

Genomics for OR4C15 Gene

Genomic Location for OR4C15 Gene

Start:
55,554,307 bp from pter
End:
55,555,419 bp from pter
Size:
1,113 bases
Orientation:
Plus strand

Genomic View for OR4C15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4C15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4C15 Gene

Regulatory Elements for OR4C15 Gene

Proteins for OR4C15 Gene

  • Protein details for OR4C15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGM1-OR4CF_HUMAN
    Recommended name:
    Olfactory receptor 4C15
    Protein Accession:
    Q8NGM1
    Secondary Accessions:
    • Q6IFE2

    Protein attributes for OR4C15 Gene

    Size:
    316 amino acids
    Molecular mass:
    35667 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04717.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=DAA04718.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR4C15 Gene

Proteomics data for OR4C15 Gene at MOPED

Post-translational modifications for OR4C15 Gene

Other Protein References for OR4C15 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR4C15 Gene

Domains for OR4C15 Gene

Gene Families for OR4C15 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4C15 Gene

UniProtKB/Swiss-Prot:

OR4CF_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGM1
genes like me logo Genes that share domains with OR4C15: view

Function for OR4C15 Gene

Molecular function for OR4C15 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4C15: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4C15 Gene

Localization for OR4C15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4C15 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4C15 Gene COMPARTMENTS Subcellular localization image for OR4C15 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4C15: view

Pathways for OR4C15 Gene

genes like me logo Genes that share pathways with OR4C15: view

Pathways by source for OR4C15 Gene

Interacting Proteins for OR4C15 Gene

Gene Ontology (GO) - Biological Process for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4C15: view

Transcripts for OR4C15 Gene

mRNA/cDNA for OR4C15 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4C15 Gene

No ASD Table

Relevant External Links for OR4C15 Gene

GeneLoc Exon Structure for
OR4C15
ECgene alternative splicing isoforms for
OR4C15

Expression for OR4C15 Gene

mRNA expression in normal human tissues for OR4C15 Gene

SOURCE GeneReport for Unigene cluster for OR4C15 Gene Hs.589003

genes like me logo Genes that share expressions with OR4C15: view

Orthologs for OR4C15 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4C15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466532 36
  • 99.37 (n)
  • 99.19 (a)
OR4C15 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 59 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia LOC100684610 36
  • 65.57 (n)
  • 64.26 (a)
OR4C15 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1211 36
  • 82.96 (n)
  • 82.96 (a)
Olfr1211 16
Olfr1211 37
  • 83 (a)
OneToMany
Olfr1212 37
  • 75 (a)
OneToMany
Olfr1213 37
  • 74 (a)
OneToMany
Olfr1214 37
  • 69 (a)
OneToMany
Olfr1215 37
  • 71 (a)
OneToMany
Olfr1216 37
  • 69 (a)
OneToMany
Olfr1217 37
  • 72 (a)
OneToMany
Olfr1218 37
  • 68 (a)
OneToMany
Olfr1219 37
  • 71 (a)
OneToMany
Olfr1220 37
  • 70 (a)
OneToMany
Olfr1221 37
  • 71 (a)
OneToMany
Olfr1222 37
  • 73 (a)
OneToMany
Olfr1223 37
  • 74 (a)
OneToMany
Olfr1224-ps1 37
  • 72 (a)
OneToMany
Olfr1225 37
  • 71 (a)
OneToMany
Olfr1226 37
  • 71 (a)
OneToMany
Olfr1228 37
  • 72 (a)
OneToMany
Olfr1229 37
  • 80 (a)
OneToMany
Olfr1232 37
  • 76 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 73 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
-- 37
  • 73 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 62 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr663 36
  • 83.07 (n)
  • 82.32 (a)
Species with no ortholog for OR4C15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4C15 Gene

ENSEMBL:
Gene Tree for OR4C15 (if available)
TreeFam:
Gene Tree for OR4C15 (if available)

Paralogs for OR4C15 Gene

Selected SIMAP similar genes for OR4C15 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4C15: view

Variants for OR4C15 Gene

Sequence variations from dbSNP and Humsavar for OR4C15 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs492480 -- 55,554,037(+) TGCTC(C/T)CATTT upstream-variant-2KB
rs505338 -- 55,553,107(+) AGTTG(A/G)AGAGT upstream-variant-2KB
rs509882 -- 55,553,579(-) ACACA(A/G)AATCT upstream-variant-2KB
rs538953 -- 55,553,088(+) CTGTG(A/G)AAATG upstream-variant-2KB
rs550331 -- 55,555,770(+) caggc(G/T)gctaa downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR4C15 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv524091 CNV Gain 19592680
nsv467886 CNV Gain 19166990
esv2751031 CNV Loss 17911159
nsv821668 CNV Loss 15273396
nsv518225 CNV Loss 19592680
dgv376e1 CNV Complex 17122850
esv782 CNV CNV 17122850
dgv12n68 CNV Loss 17160897
esv2751032 CNV Loss 17911159
dgv377e1 CNV Complex 17122850
nsv428256 CNV Loss 18775914
nsv522846 CNV Gain 19592680

Relevant External Links for OR4C15 Gene

HapMap Linkage Disequilibrium report
OR4C15

Disorders for OR4C15 Gene

No disorders were found for OR4C15 Gene.

No data available for UniProtKB/Swiss-Prot for OR4C15 Gene

Publications for OR4C15 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR4C15 Gene

  • antibodies-online proteins for OR4C15
  • antibodies-online antibodies for OR4C15
  • antibodies-online kits for OR4C15

Sources for OR4C15 Gene

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