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Aliases for OR4C15 Gene

Aliases for OR4C15 Gene

  • Olfactory Receptor, Family 4, Subfamily C, Member 15 2 3
  • Olfactory Receptor OR11-127 3 4
  • Olfactory Receptor OR11-134 3 4
  • Olfactory Receptor 4C15 3
  • OR11-127 3
  • OR11-134 3

External Ids for OR4C15 Gene

Previous GeneCards Identifiers for OR4C15 Gene

  • GC11U990542
  • GC11P055078
  • GC11P055321

Summaries for OR4C15 Gene

Entrez Gene Summary for OR4C15 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4C15 Gene

OR4C15 (Olfactory Receptor, Family 4, Subfamily C, Member 15) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4C15 Gene

  • Odorant receptor.

Gene Wiki entry for OR4C15 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4C15 Gene

Genomics for OR4C15 Gene

Regulatory Elements for OR4C15 Gene

Genomic Location for OR4C15 Gene

55,554,307 bp from pter
55,555,419 bp from pter
1,113 bases
Plus strand

Genomic View for OR4C15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4C15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4C15 Gene

Proteins for OR4C15 Gene

  • Protein details for OR4C15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 4C15
    Protein Accession:
    Secondary Accessions:
    • Q6IFE2

    Protein attributes for OR4C15 Gene

    316 amino acids
    Molecular mass:
    35667 Da
    Quaternary structure:
    No Data Available
    • Sequence=DAA04717.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=DAA04718.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR4C15 Gene

Proteomics data for OR4C15 Gene at MOPED

Post-translational modifications for OR4C15 Gene

  • Glycosylation at Asn3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4C15 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR4C15

No data available for DME Specific Peptides for OR4C15 Gene

Domains for OR4C15 Gene

Gene Families for OR4C15 Gene

Protein Domains for OR4C15 Gene

Suggested Antigen Peptide Sequences for OR4C15 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4C15: view

Function for OR4C15 Gene

Molecular function for OR4C15 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4C15: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR4C15

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4C15 Gene

Localization for OR4C15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4C15 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR4C15 Gene COMPARTMENTS Subcellular localization image for OR4C15 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4C15: view

Pathways for OR4C15 Gene

genes like me logo Genes that share pathways with OR4C15: view

Pathways by source for OR4C15 Gene

Interacting Proteins for OR4C15 Gene

Gene Ontology (GO) - Biological Process for OR4C15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4C15: view

Transcripts for OR4C15 Gene

mRNA/cDNA for OR4C15 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR4C15

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR4C15 Gene

No ASD Table

Relevant External Links for OR4C15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR4C15 Gene

mRNA expression in normal human tissues for OR4C15 Gene

SOURCE GeneReport for Unigene cluster for OR4C15 Gene Hs.589003

genes like me logo Genes that share expressions with OR4C15: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR4C15 Gene

Orthologs for OR4C15 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4C15 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC100684610 35
  • 65.57 (n)
  • 64.26 (a)
OR4C15 36
  • 85 (a)
(Mus musculus)
Mammalia Olfr1211 35
  • 82.96 (n)
  • 82.96 (a)
Olfr1211 16
Olfr1211 36
  • 83 (a)
Olfr1212 36
  • 75 (a)
Olfr1213 36
  • 74 (a)
Olfr1214 36
  • 69 (a)
Olfr1215 36
  • 71 (a)
Olfr1216 36
  • 69 (a)
Olfr1217 36
  • 72 (a)
Olfr1218 36
  • 68 (a)
Olfr1219 36
  • 71 (a)
Olfr1220 36
  • 70 (a)
Olfr1221 36
  • 71 (a)
Olfr1222 36
  • 73 (a)
Olfr1223 36
  • 74 (a)
Olfr1224-ps1 36
  • 72 (a)
Olfr1225 36
  • 71 (a)
Olfr1226 36
  • 71 (a)
Olfr1228 36
  • 72 (a)
Olfr1229 36
  • 80 (a)
Olfr1232 36
  • 76 (a)
(Pan troglodytes)
Mammalia LOC466532 35
  • 99.37 (n)
  • 99.19 (a)
OR4C15 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Olr663 35
  • 83.07 (n)
  • 82.32 (a)
(Bos Taurus)
Mammalia -- 36
  • 59 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
-- 36
  • 74 (a)
-- 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 62 (a)
Species with no ortholog for OR4C15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4C15 Gene

Gene Tree for OR4C15 (if available)
Gene Tree for OR4C15 (if available)

Paralogs for OR4C15 Gene

(445) SIMAP similar genes for OR4C15 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR4C15: view

Variants for OR4C15 Gene

Sequence variations from dbSNP and Humsavar for OR4C15 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs492480 -- 55,554,037(+) TGCTC(C/T)CATTT upstream-variant-2KB
rs505338 -- 55,553,107(+) AGTTG(A/G)AGAGT upstream-variant-2KB
rs509882 -- 55,553,579(-) ACACA(A/G)AATCT upstream-variant-2KB
rs538953 -- 55,553,088(+) CTGTG(A/G)AAATG upstream-variant-2KB
rs550331 -- 55,555,770(+) caggc(G/T)gctaa downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR4C15 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv524091 CNV Gain 19592680
nsv467886 CNV Gain 19166990
esv2751031 CNV Loss 17911159
nsv821668 CNV Loss 15273396
nsv518225 CNV Loss 19592680
dgv376e1 CNV Complex 17122850
esv782 CNV CNV 17122850
dgv12n68 CNV Loss 17160897
esv2751032 CNV Loss 17911159
dgv377e1 CNV Complex 17122850
nsv428256 CNV Loss 18775914
nsv522846 CNV Gain 19592680

Relevant External Links for OR4C15 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4C15 Gene

Disorders for OR4C15 Gene

No disorders were found for OR4C15 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR4C15 Gene

Publications for OR4C15 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR4C15 Gene

Sources for OR4C15 Gene

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