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Aliases for OR4C13 Gene

Aliases for OR4C13 Gene

  • Olfactory Receptor, Family 4, Subfamily C, Member 13 2 3
  • Olfactory Receptor OR11-260 4

External Ids for OR4C13 Gene

Summaries for OR4C13 Gene

Entrez Gene Summary for OR4C13 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4C13 Gene

OR4C13 (Olfactory Receptor, Family 4, Subfamily C, Member 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4C13 Gene

  • Odorant receptor.

Gene Wiki entry for OR4C13 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4C13 Gene

Genomics for OR4C13 Gene

Genomic Location for OR4C13 Gene

Start:
49,952,391 bp from pter
End:
49,953,419 bp from pter
Size:
1,029 bases
Orientation:
Plus strand

Genomic View for OR4C13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4C13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4C13 Gene

Regulatory Elements for OR4C13 Gene

Proteins for OR4C13 Gene

  • Protein details for OR4C13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGP0-OR4CD_HUMAN
    Recommended name:
    Olfactory receptor 4C13
    Protein Accession:
    Q8NGP0
    Secondary Accessions:
    • A6NJJ3
    • B9EH30
    • Q6IF48
    • Q96R68

    Protein attributes for OR4C13 Gene

    Size:
    309 amino acids
    Molecular mass:
    34582 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4C13 Gene

Proteomics data for OR4C13 Gene at MOPED

Post-translational modifications for OR4C13 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn6 and Asn87

Other Protein References for OR4C13 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR4C13 Gene

Domains for OR4C13 Gene

Gene Families for OR4C13 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4C13 Gene

UniProtKB/Swiss-Prot:

OR4CD_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGP0
genes like me logo Genes that share domains with OR4C13: view

Function for OR4C13 Gene

Molecular function for OR4C13 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4C13: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4C13 Gene

Localization for OR4C13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4C13 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4C13 Gene COMPARTMENTS Subcellular localization image for OR4C13 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4C13: view

Pathways for OR4C13 Gene

genes like me logo Genes that share pathways with OR4C13: view

Pathways by source for OR4C13 Gene

Interacting Proteins for OR4C13 Gene

Gene Ontology (GO) - Biological Process for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4C13: view

Transcripts for OR4C13 Gene

mRNA/cDNA for OR4C13 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4C13 Gene

No ASD Table

Relevant External Links for OR4C13 Gene

GeneLoc Exon Structure for
OR4C13
ECgene alternative splicing isoforms for
OR4C13

Expression for OR4C13 Gene

mRNA expression in normal human tissues for OR4C13 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR4C13 Gene

SOURCE GeneReport for Unigene cluster for OR4C13 Gene Hs.553668

genes like me logo Genes that share expressions with OR4C13: view

Orthologs for OR4C13 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4C13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC746422 36
  • 98.38 (n)
  • 96.76 (a)
OR4C13 37
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 76 (a)
ManyToMany
-- 37
  • 76 (a)
ManyToMany
LOC515790 36
  • 80.89 (n)
  • 72.64 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 82 (a)
ManyToMany
LOC483566 36
  • 84.25 (n)
  • 78.64 (a)
mouse
(Mus musculus)
Mammalia Olfr1202 37
  • 74 (a)
ManyToMany
Olfr1257 36
  • 80.8 (n)
  • 78.64 (a)
Olfr1257 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 78 (a)
ManyToMany
-- 37
  • 76 (a)
ManyToMany
-- 37
  • 77 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr722 36
  • 80.69 (n)
  • 79.55 (a)
Species with no ortholog for OR4C13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4C13 Gene

ENSEMBL:
Gene Tree for OR4C13 (if available)
TreeFam:
Gene Tree for OR4C13 (if available)

Paralogs for OR4C13 Gene

Selected SIMAP similar genes for OR4C13 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR4C13 Gene

genes like me logo Genes that share paralogs with OR4C13: view

Variants for OR4C13 Gene

Sequence variations from dbSNP and Humsavar for OR4C13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1996982 -- 49,951,067(+) ACTTT(G/T)CAGAA upstream-variant-2KB
rs2866868 -- 49,951,922(-) AAGGT(C/T)TTTGT upstream-variant-2KB
rs4268488 -- 49,952,848(+) CTGCT(A/T)GTGGG reference, synonymous-codon
rs11040677 -- 49,953,616(+) TCCTT(C/T)TAATA downstream-variant-500B
rs11040678 -- 49,953,685(+) ACTGA(A/G)GGAGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR4C13 Gene

Variant ID Type Subtype PubMed ID
nsv897491 CNV Gain 21882294
esv33425 CNV Gain 17666407
nsv467876 CNV Gain 19166990
nsv897496 CNV Gain 21882294

Relevant External Links for OR4C13 Gene

HapMap Linkage Disequilibrium report
OR4C13

Disorders for OR4C13 Gene

No disorders were found for OR4C13 Gene.

No data available for UniProtKB/Swiss-Prot for OR4C13 Gene

Publications for OR4C13 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR4C13 Gene

  • antibodies-online peptides for OR4C13
  • antibodies-online antibodies for OR4C13
  • antibodies-online kits for OR4C13

Sources for OR4C13 Gene

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