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Aliases for OR4C13 Gene

Aliases for OR4C13 Gene

  • Olfactory Receptor Family 4 Subfamily C Member 13 2 3 5
  • Olfactory Receptor, Family 4, Subfamily C, Member 13 2
  • Olfactory Receptor OR11-260 4

External Ids for OR4C13 Gene

Previous GeneCards Identifiers for OR4C13 Gene

  • GC11U990544
  • GC11P049930

Summaries for OR4C13 Gene

Entrez Gene Summary for OR4C13 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4C13 Gene

OR4C13 (Olfactory Receptor Family 4 Subfamily C Member 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR4C46.

UniProtKB/Swiss-Prot for OR4C13 Gene

  • Odorant receptor.

Gene Wiki entry for OR4C13 Gene

Additional gene information for OR4C13 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4C13 Gene

Genomics for OR4C13 Gene

Regulatory Elements for OR4C13 Gene

Genomic Locations for OR4C13 Gene

Genomic Locations for OR4C13 Gene
1,029 bases
Plus strand

Genomic View for OR4C13 Gene

Genes around OR4C13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR4C13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR4C13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4C13 Gene

Proteins for OR4C13 Gene

  • Protein details for OR4C13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 4C13
    Protein Accession:
    Secondary Accessions:
    • A6NJJ3
    • B9EH30
    • Q6IF48
    • Q96R68

    Protein attributes for OR4C13 Gene

    309 amino acids
    Molecular mass:
    34582 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4C13 Gene

Post-translational modifications for OR4C13 Gene

  • Glycosylation at posLast=66 and posLast=8787
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4C13 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4C13 Gene

Domains & Families for OR4C13 Gene

Gene Families for OR4C13 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR4C13 Gene

Suggested Antigen Peptide Sequences for OR4C13 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4C13: view

Function for OR4C13 Gene

Molecular function for OR4C13 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4C13: view

Phenotypes for OR4C13 Gene

genes like me logo Genes that share phenotypes with OR4C13: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR4C13 Gene

Localization for OR4C13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4C13 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR4C13 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4C13: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR4C13 Gene

Pathways & Interactions for OR4C13 Gene

genes like me logo Genes that share pathways with OR4C13: view

Pathways by source for OR4C13 Gene

Interacting Proteins for OR4C13 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 12)
Selected Interacting proteins: ENSP00000452277 Q8NGP0-OR4CD_HUMAN for OR4C13 Gene via STRING IID

Gene Ontology (GO) - Biological Process for OR4C13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR4C13: view

No data available for SIGNOR curated interactions for OR4C13 Gene

Drugs & Compounds for OR4C13 Gene

No Compound Related Data Available

Transcripts for OR4C13 Gene

mRNA/cDNA for OR4C13 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR4C13 Gene

No ASD Table

Relevant External Links for OR4C13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR4C13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR4C13 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR4C13 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR4C13 Gene:


SOURCE GeneReport for Unigene cluster for OR4C13 Gene:

genes like me logo Genes that share expression patterns with OR4C13: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR4C13 Gene

Orthologs for OR4C13 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4C13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC746422 33
  • 98.38 (n)
OR4C13 34
  • 97 (a)
(Canis familiaris)
Mammalia LOC483566 33
  • 84.25 (n)
-- 34
  • 82 (a)
(Bos Taurus)
Mammalia LOC515790 33
  • 80.89 (n)
-- 34
  • 76 (a)
-- 34
  • 76 (a)
(Mus musculus)
Mammalia Olfr1257 33 16
  • 80.8 (n)
Olfr1202 34
  • 74 (a)
(Rattus norvegicus)
Mammalia Olr722 33
  • 80.69 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 78 (a)
-- 34
  • 77 (a)
-- 34
  • 76 (a)
Species where no ortholog for OR4C13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4C13 Gene

Gene Tree for OR4C13 (if available)
Gene Tree for OR4C13 (if available)

Paralogs for OR4C13 Gene

Paralogs for OR4C13 Gene

(446) SIMAP similar genes for OR4C13 Gene using alignment to 1 proteins: Pseudogenes for OR4C13 Gene

genes like me logo Genes that share paralogs with OR4C13: view

Variants for OR4C13 Gene

Sequence variations from dbSNP and Humsavar for OR4C13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs11040677 -- 49,953,616(+) TCCTT(C/T)TAATA downstream-variant-500B
rs11040678 -- 49,953,685(+) ACTGA(A/G)GGAGG downstream-variant-500B
rs111385765 -- 49,952,155(+) ATTAA(C/G/T)TGTTC upstream-variant-2KB
rs111612557 -- 49,952,992(+) AATAC(C/T)CACAC reference, synonymous-codon
rs112669721 -- 49,951,032(+) TAACA(A/C)ACTTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR4C13 Gene

Variant ID Type Subtype PubMed ID
nsv983016 CNV duplication 23825009
nsv554394 CNV loss 21841781
nsv467876 CNV gain 19166990
nsv1048074 CNV gain 25217958
esv3892002 CNV gain 25118596
esv3626326 CNV gain 21293372
esv33425 CNV gain 17666407
esv2760533 CNV gain+loss 21179565
dgv1813n54 CNV gain 21841781
dgv1130n100 CNV gain 25217958
dgv1128n100 CNV gain 25217958

Variation tolerance for OR4C13 Gene

Residual Variation Intolerance Score: 90.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.26; 52.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR4C13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4C13 Gene

Disorders for OR4C13 Gene

Relevant External Links for OR4C13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR4C13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR4C13 Gene

Publications for OR4C13 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 60
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 60
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for OR4C13 Gene

Sources for OR4C13 Gene

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