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Aliases for OR4A47 Gene

Aliases for OR4A47 Gene

  • Olfactory Receptor, Family 4, Subfamily A, Member 47 2 3
  • Olfactory Receptor OR11-113 3 4
  • Olfactory Receptor 4A47 3
  • OR11-113 3

External Ids for OR4A47 Gene

Previous GeneCards Identifiers for OR4A47 Gene

  • GC11U900133

Summaries for OR4A47 Gene

Entrez Gene Summary for OR4A47 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4A47 Gene

OR4A47 (Olfactory Receptor, Family 4, Subfamily A, Member 47) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4A47 Gene

  • Odorant receptor.

Gene Wiki entry for OR4A47 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4A47 Gene

Genomics for OR4A47 Gene

Regulatory Elements for OR4A47 Gene

Genomic Location for OR4A47 Gene

Start:
48,483,466 bp from pter
End:
48,489,780 bp from pter
Size:
6,315 bases
Orientation:
Plus strand

Genomic View for OR4A47 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR4A47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4A47 Gene

Proteins for OR4A47 Gene

  • Protein details for OR4A47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IF82-O4A47_HUMAN
    Recommended name:
    Olfactory receptor 4A47
    Protein Accession:
    Q6IF82
    Secondary Accessions:

    Protein attributes for OR4A47 Gene

    Size:
    309 amino acids
    Molecular mass:
    34760 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4A47 Gene

Proteomics data for OR4A47 Gene at MOPED

Post-translational modifications for OR4A47 Gene

  • Glycosylation at Asn6 and Asn87
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4A47 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4A47 Gene

Domains for OR4A47 Gene

Gene Families for OR4A47 Gene

HGNC:
  • OR4 :GPCR / Class A : Olfactory receptors

Protein Domains for OR4A47 Gene

Suggested Antigen Peptide Sequences for OR4A47 Gene

Graphical View of Domain Structure for InterPro Entry

Q6IF82

UniProtKB/Swiss-Prot:

O4A47_HUMAN :
  • Q6IF82
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4A47: view

Function for OR4A47 Gene

Molecular function for OR4A47 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4A47: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR4A47 Gene

Localization for OR4A47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4A47 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR4A47 Gene COMPARTMENTS Subcellular localization image for OR4A47 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4A47: view

Pathways for OR4A47 Gene

genes like me logo Genes that share pathways with OR4A47: view

Pathways by source for OR4A47 Gene

Interacting Proteins for OR4A47 Gene

Gene Ontology (GO) - Biological Process for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4A47: view

Transcripts for OR4A47 Gene

mRNA/cDNA for OR4A47 Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4A47 Gene

No ASD Table

Relevant External Links for OR4A47 Gene

GeneLoc Exon Structure for
OR4A47
ECgene alternative splicing isoforms for
OR4A47

Expression for OR4A47 Gene

mRNA expression in normal human tissues for OR4A47 Gene

SOURCE GeneReport for Unigene cluster for OR4A47 Gene Hs.554532

genes like me logo Genes that share expressions with OR4A47: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR4A47 Gene

Orthologs for OR4A47 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4A47 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC745857 35
  • 98.92 (n)
  • 97.73 (a)
OR4A47 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 76 (a)
OneToMany
-- 36
  • 74 (a)
OneToMany
-- 36
  • 78 (a)
OneToMany
-- 36
  • 79 (a)
OneToMany
-- 36
  • 77 (a)
OneToMany
-- 36
  • 75 (a)
OneToMany
LOC785969 35
  • 84.31 (n)
  • 79.08 (a)
dog
(Canis familiaris)
Mammalia LOC100683879 35
  • 87.01 (n)
  • 85.06 (a)
OR4A47 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1256 35
  • 83.01 (n)
  • 81.05 (a)
Olfr1256 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR4A47 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 64 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr720 35
  • 83.22 (n)
  • 81.37 (a)
Species with no ortholog for OR4A47:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4A47 Gene

ENSEMBL:
Gene Tree for OR4A47 (if available)
TreeFam:
Gene Tree for OR4A47 (if available)

Paralogs for OR4A47 Gene

Selected SIMAP similar genes for OR4A47 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR4A47 Gene

genes like me logo Genes that share paralogs with OR4A47: view

Variants for OR4A47 Gene

Sequence variations from dbSNP and Humsavar for OR4A47 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1945184 -- 48,483,496(+) TCCTT(G/T)TGAGT utr-variant-5-prime
rs2213057 -- 48,483,710(+) ATTTA(A/C)AAAAT intron-variant
rs4122071 -- 48,483,527(+) TCATA(A/G)ATAAG intron-variant
rs4881997 -- 48,484,994(+) tttga(A/G)gtgag intron-variant
rs4882085 -- 48,483,017(+) ACTAT(A/C/G)CTTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR4A47 Gene

Variant ID Type Subtype PubMed ID
dgv1091n71 CNV Gain 21882294
nsv467871 CNV Gain 19166990
nsv428253 CNV Loss 18775914
nsv469953 CNV Loss 18288195
dgv366e1 CNV Complex 17122850
esv542 CNV CNV 17122850
nsv897333 CNV Gain 21882294
dgv48e55 CNV Loss 17911159
nsv469954 CNV Gain 18288195
nsv832144 CNV Loss 17160897
nsv897341 CNV Gain 21882294
dgv1095n71 CNV Loss 21882294
nsv897343 CNV Gain 21882294
nsv467874 CNV Gain 19166990

Relevant External Links for OR4A47 Gene

HapMap Linkage Disequilibrium report
OR4A47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4A47 Gene

Disorders for OR4A47 Gene

No disorders were found for OR4A47 Gene.

No data available for UniProtKB/Swiss-Prot for OR4A47 Gene

Publications for OR4A47 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  3. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. (PMID: 24144296) Cheng C.Y. … Baird P.N. (Am. J. Hum. Genet. 2013) 3
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR4A47 Gene

Sources for OR4A47 Gene

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