OR3A4P Gene
pseudogene GIFtS: 35
GCID: GC17P003222
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olfactory receptor, family 3, subfamily A, member 4 pseudogene(Previous names: olfactory receptor, family 3, subfamily A, member 4 )
(Previous symbol: OR3A4)
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Aliases
for OR3A4P gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Olfactory Receptor, Family 3, Subfamily A, Member 4 Pseudogene1 2 | | OR17-132 | | OR3A41 2 3 | | OR17-162 | | OR17-242 3 | | OR17-252 | | OR3A5P2 3 | | OR242 | | Olfactory Receptor, Family 3, Subfamily A, Member 41 | | OR252 | | OLFRA052 | | Olfactory Receptor 17-243 | | OLFRA062 | | Olfactory Receptor 3A53 |
Export aliases for OR3A4P gene to outside databasesPrevious GC identifers: GC17P003214 GC17P003216 |
Summaries
for OR3A4P gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OR3A4P:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers theperception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors(GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with manyneurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction ofodorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptorgene is transcribed and contains an intact ORF, but it is predicted to be a pseudogene due to a poorly conserved7-transmembrane domain structure. (provided by RefSeq, Sep 2008)
UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883Function: Odorant receptor (Potential)
Gene Wiki entry for OR3A4P (OR3A4)
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Genomic Views
for OR3A4P gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for OR3A4P
Other transcription factors
Search SABiosciences Chromatin IP Primers for OR3A4P
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR3A4P |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3OR3A4P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P003222: view genomic region
(about GC identifiers)
Start:
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3,213,280 bp from pter |
End:
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3,215,225 bp from pter |
Size:
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1,946 bases |
Orientation:
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plus strand |
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Proteins
for OR3A4P gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883 (See
protein sequence)Recommended Name: Putative olfactory receptor 3A4 Size: 348 amino acids; 37194 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Caution: Could be the product of a pseudogene
Secondary accessions: Q96R24Explore the universe of human proteins at neXtProt for OR3A4P: NX_P47883
OR3A4P Protein expression data from MOPED and PaxDb: --
Reactome Protein details: P47883
Human Recombinant Protein Products:
OR3A4P Antibody Products:
Assay Products for OR3A4P: |
Protein
Domains /
Families
for OR3A4P gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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OR3A4P for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P47883ProtoNet protein and cluster: P47883 UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for OR3A4P gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Function Summary:
UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883Function: Odorant receptor (Potential) Genatlas biochemistry entry for OR3A4P:olfactory receptor gene family 3,subfamily A,member 4,pseudogene,G protein coupled receptor superfamily
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
1 GenomeRNAi human phenotype for OR3A4P:
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Pathways & Interactions
for OR3A4P gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways About this table 
See pathways by source
| Super-pathway | contained gene-specific pathways |
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| 1 | Signaling by GPCR | | | 2 | GPCRs, Other | | | 3 | Olfactory transduction | | | 4 | Class A/1 (Rhodopsin-like receptors) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for OR3A4P
4 
Reactome Pathways for OR3A4P
OR3A4P for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR3A4P
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Drugs & Compounds
for OR3A4P gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for OR3A4P
Search CenterWatch for drugs/clinical trials and news about OR3A4P
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Transcripts
for OR3A4P gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for OR3A4P gene: NM_001005334.1 Unigene Cluster for OR3A4P: Olfactory receptor, family 3, subfamily A, member 4 pseudogene Hs.632245 Unigene Representative Sequence: BC1368753 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000323164 ENST00000574571 ENST00000545655(uc002fvi.2)
Additional cDNA sequence: AJ459867.1 BC136874.1 BC136875.1 NR_024128.1
GeneLoc Exon Structure
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Expression
for OR3A4P gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OR3A4P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCTGTGAAG
About this image
SOURCE GeneReport for Unigene cluster: Hs.632245
SABiosciences Custom PCR Arrays for OR3A4P
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OR3A4P
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat OR3A4P | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR3A4P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR3A4P | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
Orthologs
for OR3A4P gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of human and mouse.
Orthologs for OR3A4P gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Olfr3995 |
olfactory receptor 399 |
-- |
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11 (45.73 cM) 74053822 |
ENSEMBL Gene Tree for OR3A4P (if available)
TreeFam Gene Tree for OR3A4P (if available) |
Paralogs
for OR3A4P gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for OR3A4P gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for OR3A4P (3213280 - 3215225 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for OR3A4P: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for OR3A4P gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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OR3A4P for disorders About GeneDecksing
1  disease for OR3A4P: About MalaCardsneuronitis
Export disorders for OR3A4P gene to outside databases
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Publications
for OR3A4P gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for OR3A4P gene integrated from 9 sources:
(articles sorted by number of sources associating them with OR3A4P) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DEFOG: a practical scheme for deciphering families of genes. (PubMed id 12213199)1, 2 Fuchs T.... Shamir R. (2002)
- Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PubMed id 8004088)1, 2 Ben-Arie N.... North M.A. (1994)
- Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity. (PubMed id 8921386)1, 9 Glusman G.... Lancet D. (1996)
- A probabilistic classifier for olfactory receptor pseudogenes. (PubMed id 16939646)1 Menashe I....Lancet D. (2006)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The human olfactory receptor gene family. (PubMed id 14983052)1 Malnic B.... Buck L.B. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PubMed id 10673334)1 Glusman G.... Lancet D. (2000)
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External Searches for OR3A4P gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing OR3A4P gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing OR3A4P gene
(According to HUGE)
About This Section
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Specialized Databases showing OR3A4P gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for OR3A4P | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for OR3A4P gene:
Search GeneIP for patents involving OR3A4P
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OR3A4P gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for OR3A4P | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OR3A4P | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OR3A4P | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OR3A4P | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OR3A4P | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OR3A4P | | OriGene Custom Protein Services for OR3A4P | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OR3A4P | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OR3A4P | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR3A4P | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR3A4P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR3A4P | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR3A4P |
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| | | | Search Tocris compounds for OR3A4P |
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 | | | OR3A4P Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
|  |  |  | | | | Search ThermoFisher Antibodies for OR3A4P |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat OR3A4P |
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