OR3A4P Gene
pseudogene GIFtS: 33
GCID: GC17P003233
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Olfactory Receptor, Family 3, Subfamily A, Member 4 Pseudogene(Previous names: olfactory receptor, family 3, subfamily A, member 4)
(Previous symbol: OR3A4)
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Aliases
for OR3A4P gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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| Aliases |
|---|
| Olfactory Receptor, Family 3, Subfamily A, Member 4 Pseudogene1 2 | | OR17-132 | | OR3A41 2 3 | | OR17-162 | | OR17-242 3 | | OR17-252 | | OR3A5P2 3 | | OR242 | | Olfactory Receptor, Family 3, Subfamily A, Member 41 | | OR252 | | OLFRA052 | | Olfactory Receptor 17-243 | | OLFRA062 | | Olfactory Receptor 3A53 |
Export aliases for OR3A4P gene to outside databasesPrevious GC identifers: GC17P003214 GC17P003216 GC17P003222 GC17P003228 |
Summaries
for OR3A4P gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Entrez Gene summary for OR3A4P Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. This olfactory receptor gene is transcribed and contains an intact ORF, but it is predicted
to be a pseudogene due to a poorly conserved 7-transmembrane domain structure. (provided by RefSeq, Sep 2008)
GeneCards Summary for OR3A4P Gene:
OR3A4P (olfactory receptor, family 3, subfamily A, member 4 pseudogene) is a pseudogene. Diseases associated with OR3A4P include neuronitis.
UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883Function: Odorant receptor (Potential)
Gene Wiki entry for OR3A4P (OR3A4) Gene
|
Genomic Views
for OR3A4P gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000017.11 NC_018928.2 NT_010718.17
Regulatory elements:
 Search for regulatory transcription factor binding sites for OR3A4P
Other transcription factors
Search Chromatin IP Primers for OR3A4P
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR3A4P |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3OR3A4P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P003233: view genomic region
(about GC identifiers)
Start:
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3,213,539 bp from pter |
End:
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3,214,740 bp from pter |
Size:
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1,202 bases |
Orientation:
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plus strand |
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Proteins
for OR3A4P gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883 (See
protein sequence)Recommended Name: Putative olfactory receptor 3A4 Size: 348 amino acids; 37194 Da
Caution: Could be the product of a pseudogene
Secondary accessions: Q96R24Explore the universe of human proteins at neXtProt for OR3A4P: NX_P47883
Post-translational modifications:  Glycosylation2 at Asn8 Reactome Protein details: P47883
OR3A4P Human Recombinant
Protein Products:OR3A4P Antibody
Products:OR3A4P Assay Products: |
Domains /
Families
for OR3A4P gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | HGNC Gene Families:
OR3: GPCR / Class A : Olfactory receptors
3 InterPro protein domains:Graphical View of Domain Structure for InterPro Entry P47883ProtoNet protein and cluster: P47883 UniProtKB/Swiss-Prot: OR3A4_HUMAN, P47883Similarity: Belongs to the G-protein coupled receptor 1 family
OR3A4P for domains About GeneDecksing
|
Function
for OR3A4P gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
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Molecular Function:
UniProtKB/Swiss-Prot Summary: OR3A4_HUMAN, P47883Function: Odorant receptor (Potential) Genatlas biochemistry entry for OR3A4P:olfactory receptor gene family 3,subfamily A,member 4,pseudogene,G protein coupled receptor superfamily
Phenotypes:
1 GenomeRNAi human phenotype for OR3A4P:
Animal Models:
Inhib. RNA
Products: |  | OriGene RNAi products in human, mouse, rat for OR3A4P
| | | Predesigned siRNA for gene silencing in human, mouse, rat OR3A4P |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for OR3A4P | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for OR3A4P  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
Localization
for OR3A4P gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
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Subcellular locations from UniProtKB/Swiss-Prot OR3A4_HUMAN, P47883: Cell membrane; Multi-pass membrane protein |
Pathways & Interactions
for OR3A4P gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
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SuperPaths for OR3A4P About See pathways by source
Pathways by source See SuperPaths
Show all pathways
2  BioSystems Pathways for OR3A4P
1  Reactome Pathway for OR3A4P
OR3A4P for pathways About GeneDecksing
Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OR3A4P
Interactions:
Search GeneGlobe Interaction Network for OR3A4P
|
Drugs & Compounds
for OR3A4P gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
TryGeneCards Plus |  Browse compounds at ApexBio
 Browse Tocris compounds for OR3A4P (OR3A4)
|
Transcripts
for OR3A4P gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for OR3A4P gene: NM_001005334.1 Unigene Cluster for OR3A4P: Olfactory receptor, family 3, subfamily A, member 4 pseudogene Hs.632245 Unigene Representative Sequence: BC1368752 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000323164 ENST00000545655(uc002fvi.2)
Inhib. RNA
Products: | | OriGene RNAi products in human, mouse, rat for OR3A4P
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat OR3A4P |
Additional mRNA sequence: AJ459867.1 BC136874.1 BC136875.1 NR_024128.1
GeneLoc Exon Structure
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Expression
for OR3A4P gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
TryGeneCards Plus | See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: AGCTGTGAAG
OR3A4P Protein expression data from MOPED1, PaxDb2 and
MaxQB3: --
SOURCE GeneReport for Unigene cluster: Hs.632245
Custom PCR Arrays for OR3A4P
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for OR3A4P
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat OR3A4P | | | QuantiTect SYBR Green Assays in human, mouse, rat OR3A4P | | | QuantiFast Probe-based Assays in human, mouse, rat OR3A4P | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
Orthologs
for OR3A4P gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of human and mouse.
Orthologs for OR3A4P gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Olfr3995 |
olfactory receptor 399 |
-- |
|
11 (45.73 cM) 74050436 |
ENSEMBL Gene Tree for OR3A4P (if available)
TreeFam Gene Tree for OR3A4P (if available) |
Paralogs
for OR3A4P gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for OR3A4P gene
Selected SIMAP similar genes for OR3A4P using alignment to 1 protein entry: OR3A4_HUMAN(see all similar genes):OR17-16 OR17-137 OR3A1 OR3A2 OR3A3 OR17-15
OR13G1 OR1C1 OR1F2P OR1J2 OR4Q3 OR2W3
OR6N1 HSA10 LOC441453 OR10G4 OR10G7 OR10R3P
OR3A4P for paralogs About GeneDecksing
|
Genomic Variants
for OR3A4P gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OR3A4P (3213539 - 3214740 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for OR3A4P: --
| | Site Specific Mutation Identification with PCR Assays |
|
Disorders
/ Diseases
for OR3A4P gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
TryGeneCards Plus | 1  disease for OR3A4P: About MalaCardsneuronitis
OR3A4P for disorders About GeneDecksing
Export disorders for OR3A4P gene to outside databases
|
Publications
for OR3A4P gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for OR3A4P gene integrated from 10 sources:
(articles sorted by number of sources associating them with OR3A4P) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DEFOG: a practical scheme for deciphering families of genes. (PubMed id 12213199)1, 2 Fuchs T.... Shamir R. (Genomics 2002)
- Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PubMed id 8004088)1, 2 Ben-Arie N.... North M.A. (Hum. Mol. Genet. 1994)
- Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity. (PubMed id 8921386)1, 9 Glusman G.... Lancet D. (Genomics 1996)
- A probabilistic classifier for olfactory receptor pseudogenes. (PubMed id 16939646)1 Menashe I....Lancet D. (BMC Bioinformatics 2006)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
- The human olfactory receptor gene family. (PubMed id 14983052)1 Malnic B.... Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
- Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PubMed id 10673334)1 Glusman G.... Lancet D. (Genomics 2000)
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External Searches for OR3A4P gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing OR3A4P gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
TryGeneCards Plus |
|
Other Databases showing OR3A4P gene
(According to HUGE)
About This Section
TryGeneCards Plus | -- |
Specialized Databases showing OR3A4P gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for OR3A4P | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
TryGeneCards Plus | Patent Information for OR3A4P gene:
Search GeneIP for patents involving OR3A4P
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for OR3A4P gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | Block miRNA regulation of human, mouse, rat OR3A4P using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing OR3A4P | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR3A4P | | Predesigned siRNA for gene silencing in human, mouse, rat OR3A4P | | | QuantiFast Probe-based Assays in human, mouse, rat OR3A4P | | QuantiTect SYBR Green Assays in human, mouse, rat OR3A4P | | | Custom PCR Arrays for OR3A4P | | Search Chromatin IP Primers for OR3A4P | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat OR3A4P | | Search GeneGlobe Interaction Network for OR3A4P | | | Search Regulatory tfbs for OR3A4P |
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 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR3A4P |
| |  |  |  |  | | | Search ThermoFisher Antibodies for OR3A4P |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat OR3A4P |
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