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Aliases for OR3A3 Gene

Aliases for OR3A3 Gene

  • Olfactory Receptor, Family 3, Subfamily A, Member 3 2 3
  • Olfactory Receptor OR17-22 3 4
  • Olfactory Receptor 17-201 3 4
  • Olfactory Receptor 3A6 3 4
  • Olfactory Receptor 3A7 3 4
  • Olfactory Receptor 3A8 3 4
  • OR17-201 3 4
  • OR3A8P 3 4
  • OR3A6 3 4
  • OR3A7 3 4
  • Olfactory Receptor, Family 3, Subfamily A, Member 8 Pseudogene 3
  • Olfactory Receptor, Family 3, Subfamily A, Member 6 3
  • Olfactory Receptor, Family 3, Subfamily A, Member 7 3
  • Olfactory Receptor 3A3 3
  • OR17-137 3
  • OR17-16 3

External Ids for OR3A3 Gene

Previous HGNC Symbols for OR3A3 Gene

  • OR3A6
  • OR3A7
  • OR3A8P

Previous GeneCards Identifiers for OR3A3 Gene

  • GC17P003638
  • GC17P003274
  • GC17P003530
  • GC17P003270
  • GC17P003323

Summaries for OR3A3 Gene

Entrez Gene Summary for OR3A3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR3A3 Gene

OR3A3 (Olfactory Receptor, Family 3, Subfamily A, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR3A1.

UniProtKB/Swiss-Prot for OR3A3 Gene

  • Odorant receptor.

Gene Wiki entry for OR3A3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR3A3 Gene

Genomics for OR3A3 Gene

Regulatory Elements for OR3A3 Gene

Genomic Location for OR3A3 Gene

3,420,568 bp from pter
3,421,533 bp from pter
966 bases
Plus strand

Genomic View for OR3A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR3A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR3A3 Gene

Proteins for OR3A3 Gene

  • Protein details for OR3A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 3A3
    Protein Accession:
    Secondary Accessions:
    • Q2VPE4
    • Q6IFM6
    • Q9P1Q4
    • Q9UBE7

    Protein attributes for OR3A3 Gene

    321 amino acids
    Molecular mass:
    34963 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI08922.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR3A3 Gene

Proteomics data for OR3A3 Gene at MOPED

Post-translational modifications for OR3A3 Gene

  • Glycosylation at Asn14
  • Modification sites at PhosphoSitePlus

Other Protein References for OR3A3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR3A3 Gene

Domains for OR3A3 Gene

Gene Families for OR3A3 Gene

  • OR3 :GPCR / Class A : Olfactory receptors

Protein Domains for OR3A3 Gene

Suggested Antigen Peptide Sequences for OR3A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • P47888
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR3A3: view

Function for OR3A3 Gene

Molecular function for OR3A3 Gene

GENATLAS Biochemistry:
olfactory receptor,family 3,subfamily A,member 3,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR3A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR3A3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR3A3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR3A3 Gene

Localization for OR3A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR3A3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR3A3 Gene COMPARTMENTS Subcellular localization image for OR3A3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR3A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR3A3: view

Pathways for OR3A3 Gene

genes like me logo Genes that share pathways with OR3A3: view

Pathways by source for OR3A3 Gene

1 KEGG pathway for OR3A3 Gene

Interacting Proteins for OR3A3 Gene

Gene Ontology (GO) - Biological Process for OR3A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction NAS 8004088
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR3A3: view

Transcripts for OR3A3 Gene

mRNA/cDNA for OR3A3 Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR3A3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR3A3 Gene

No ASD Table

Relevant External Links for OR3A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR3A3 Gene

mRNA expression in normal human tissues for OR3A3 Gene

SOURCE GeneReport for Unigene cluster for OR3A3 Gene Hs.532689

genes like me logo Genes that share expressions with OR3A3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR3A3 Gene

Orthologs for OR3A3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR3A3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC508980 35
  • 83.49 (n)
  • 81.79 (a)
-- 36
  • 72 (a)
(Canis familiaris)
Mammalia OR01E11 35
  • 83.12 (n)
  • 81.53 (a)
-- 36
  • 71 (a)
(Mus musculus)
Mammalia Olfr411 35
  • 81.21 (n)
  • 78.66 (a)
Olfr411 16
Olfr399 36
  • 72 (a)
(Pan troglodytes)
Mammalia LOC454428 35
  • 96.57 (n)
  • 93.77 (a)
OR3A3 36
  • 94 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 62 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 44 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 42 (a)
Species with no ortholog for OR3A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR3A3 Gene

Gene Tree for OR3A3 (if available)
Gene Tree for OR3A3 (if available)

Paralogs for OR3A3 Gene

Paralogs for OR3A3 Gene

Selected SIMAP similar genes for OR3A3 Gene using alignment to 1 proteins: Pseudogenes for OR3A3 Gene

genes like me logo Genes that share paralogs with OR3A3: view

Variants for OR3A3 Gene

Sequence variations from dbSNP and Humsavar for OR3A3 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs227787 - 3,421,516(-) TCGCT(C/T)CCCCA reference, missense
rs227788 -- 3,420,792(+) AACCT(A/G)TCAGT synonymous-codon, reference
rs227789 -- 3,420,710(+) CACAA(C/T)TGGGG reference, missense
rs227790 -- 3,419,530(-) tgtgg(C/T)gagaa upstream-variant-2KB
rs769432 - 3,420,961(+) ACCGA(C/T)TCCTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR3A3 Gene

Variant ID Type Subtype PubMed ID
esv2660206 CNV Deletion 23128226
nsv907553 CNV Loss 21882294
nsv833341 CNV Loss 17160897
nsv521277 CNV Gain 19592680

Relevant External Links for OR3A3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR3A3 Gene

Disorders for OR3A3 Gene

Relevant External Links for OR3A3

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for OR3A3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR3A3 Gene

Publications for OR3A3 Gene

  1. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PMID: 8004088) Ben-Arie N. … North M.A. (Hum. Mol. Genet. 1994) 2 3 4
  2. Distribution of olfactory receptor genes in the human genome. (PMID: 9500546) Rouquier S. … Giorgi D. (Nat. Genet. 1998) 2 3
  3. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 3 4
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  5. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR3A3 Gene

Sources for OR3A3 Gene

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