Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR2W5 Gene

Aliases for OR2W5 Gene

  • Olfactory Receptor, Family 2, Subfamily W, Member 5 (Gene/Pseudogene) 2 3
  • OR2W5P 3 4
  • Olfactory Receptor, Family 2, Subfamily W, Member 5 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily W, Member 5 2
  • Putative Olfactory Receptor 2W5 3
  • Olfactory Receptor 2W5 3
  • OST722 3

External Ids for OR2W5 Gene

Previous HGNC Symbols for OR2W5 Gene

  • OR2W5P

Previous GeneCards Identifiers for OR2W5 Gene

  • GC01P244595
  • GC01P243960
  • GC01P245721
  • GC01P247654

Summaries for OR2W5 Gene

Entrez Gene Summary for OR2W5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene has a coding sequence that is comparable in length to other olfactory receptor genes, but it should be noted that a frameshift is present in the 3' coding region that disrupts the 7-transmembrane domain structure in the protein. It is unclear if the protein can function as an olfactory receptor or if an alternate function is served. For this reason, this gene has also been interpreted to be a pseudogene. [provided by RefSeq, Jan 2010]

GeneCards Summary for OR2W5 Gene

OR2W5 (Olfactory Receptor, Family 2, Subfamily W, Member 5 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR2W5 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2W5 Gene

Genomics for OR2W5 Gene

Regulatory Elements for OR2W5 Gene

Genomic Location for OR2W5 Gene

Start:
247,491,068 bp from pter
End:
247,492,409 bp from pter
Size:
1,342 bases
Orientation:
Plus strand

Genomic View for OR2W5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2W5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2W5 Gene

Proteins for OR2W5 Gene

  • Protein details for OR2W5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFC9-OR2W5_HUMAN
    Recommended name:
    Putative olfactory receptor 2W5
    Protein Accession:
    A6NFC9
    Secondary Accessions:
    • B9EH85

    Protein attributes for OR2W5 Gene

    Size:
    320 amino acids
    Molecular mass:
    35528 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2W5 Gene

Proteomics data for OR2W5 Gene at MOPED

Post-translational modifications for OR2W5 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2W5 Gene

Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2W5 Gene

Domains for OR2W5 Gene

Gene Families for OR2W5 Gene

HGNC:
  • OR2 :GPCR / Class A : Olfactory receptors

Protein Domains for OR2W5 Gene

Suggested Antigen Peptide Sequences for OR2W5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFC9

UniProtKB/Swiss-Prot:

OR2W5_HUMAN :
  • A6NFC9
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2W5: view

Function for OR2W5 Gene

Molecular function for OR2W5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR2W5: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR2W5 Gene

Localization for OR2W5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2W5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR2W5: view

No data available for Subcellular locations from COMPARTMENTS for OR2W5 Gene

Pathways for OR2W5 Gene

genes like me logo Genes that share pathways with OR2W5: view

Pathways by source for OR2W5 Gene

Interacting Proteins for OR2W5 Gene

Gene Ontology (GO) - Biological Process for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2W5: view

Transcripts for OR2W5 Gene

mRNA/cDNA for OR2W5 Gene

(9) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2W5 Gene

Olfactory receptor, family 2, subfamily W, member 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR2W5 Gene

No ASD Table

Relevant External Links for OR2W5 Gene

GeneLoc Exon Structure for
OR2W5
ECgene alternative splicing isoforms for
OR2W5

Expression for OR2W5 Gene

mRNA expression in normal human tissues for OR2W5 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR2W5 Gene

SOURCE GeneReport for Unigene cluster for OR2W5 Gene Hs.591526

genes like me logo Genes that share expressions with OR2W5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR2W5 Gene

Orthologs for OR2W5 Gene

Evolution for OR2W5 Gene

ENSEMBL:
Gene Tree for OR2W5 (if available)
TreeFam:
Gene Tree for OR2W5 (if available)

No data available for Orthologs for OR2W5 Gene

Paralogs for OR2W5 Gene

Selected SIMAP similar genes for OR2W5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2W5: view

No data available for Paralogs for OR2W5 Gene

Variants for OR2W5 Gene

Sequence variations from dbSNP and Humsavar for OR2W5 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs10733114 -- 247,490,322(+) AAATC(A/C)TCAAT upstream-variant-2KB
rs10754563 -- 247,489,301(+) ATCCT(G/T)TTCAG upstream-variant-2KB
rs10802516 -- 247,490,110(+) GCTCA(C/T)AGCAT upstream-variant-2KB
rs10925061 -- 247,491,691(+) ATGTC(C/T)TGTGA synonymous-codon, reference
rs11587507 -- 247,489,069(+) AAGCA(C/T)TGGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR2W5 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
dgv115n67 CNV Loss 20364138
esv2675635 CNV Deletion 23128226
esv2727818 CNV Deletion 23290073
nsv827764 CNV Loss 20364138

Relevant External Links for OR2W5 Gene

HapMap Linkage Disequilibrium report
OR2W5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2W5 Gene

Disorders for OR2W5 Gene

Relevant External Links for OR2W5

Genetic Association Database (GAD)
OR2W5
genes like me logo Genes that share disorders with OR2W5: view

No data available for UniProtKB/Swiss-Prot for OR2W5 Gene

Publications for OR2W5 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Germline genomic variants associated with childhood acute lymphoblastic leukemia. (PMID: 19684603) Trevino L.R. … Relling M.V. (Nat. Genet. 2009) 48

Products for OR2W5 Gene

Sources for OR2W5 Gene

Back to Top

Content