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Aliases for OR2W1 Gene

Aliases for OR2W1 Gene

  • Olfactory Receptor, Family 2, Subfamily W, Member 1 2 3
  • Olfactory Receptor OR6-13 3 4
  • Hs6M1-15 3 4
  • Olfactory Receptor 2W1 3

External Ids for OR2W1 Gene

Previous GeneCards Identifiers for OR2W1 Gene

  • GC06M029069
  • GC06M028782
  • GC06M029119
  • GC06M029011
  • GC06Mo28942

Summaries for OR2W1 Gene

Entrez Gene Summary for OR2W1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2W1 Gene

OR2W1 (Olfactory Receptor, Family 2, Subfamily W, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2C1.

UniProtKB/Swiss-Prot for OR2W1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2W1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2W1 Gene

Genomics for OR2W1 Gene

Regulatory Elements for OR2W1 Gene

Genomic Location for OR2W1 Gene

29,044,213 bp from pter
29,045,240 bp from pter
1,028 bases
Minus strand

Genomic View for OR2W1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2W1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR2W1 Gene

  • Protein details for OR2W1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2W1
    Protein Accession:
    Secondary Accessions:
    • B0S7Y5
    • Q5JNZ1
    • Q6IEU0
    • Q96R17
    • Q9GZL0
    • Q9GZL1

    Protein attributes for OR2W1 Gene

    320 amino acids
    Molecular mass:
    36101 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2W1 Gene

Proteomics data for OR2W1 Gene at MOPED

Post-translational modifications for OR2W1 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2W1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR2W1 Gene

Domains for OR2W1 Gene

Gene Families for OR2W1 Gene

Protein Domains for OR2W1 Gene

Suggested Antigen Peptide Sequences for OR2W1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2W1: view

Function for OR2W1 Gene

Molecular function for OR2W1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 2,subfamily W,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2W1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2W1: view

Phenotypes for OR2W1 Gene

genes like me logo Genes that share phenotypes with OR2W1: view

Animal Model Products

CRISPR Products

miRNA for OR2W1 Gene

miRTarBase miRNAs that target OR2W1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2W1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for OR2W1 Gene

Localization for OR2W1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2W1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR2W1 Gene COMPARTMENTS Subcellular localization image for OR2W1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2W1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2W1: view

Pathways for OR2W1 Gene

genes like me logo Genes that share pathways with OR2W1: view

Pathways by source for OR2W1 Gene

1 KEGG pathway for OR2W1 Gene

Interacting Proteins for OR2W1 Gene

Gene Ontology (GO) - Biological Process for OR2W1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2W1: view

Transcripts for OR2W1 Gene

mRNA/cDNA for OR2W1 Gene

(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2W1 Gene

Olfactory receptor, family 2, subfamily W, member 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2W1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2W1 Gene

No ASD Table

Relevant External Links for OR2W1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2W1 Gene

mRNA expression in normal human tissues for OR2W1 Gene

mRNA differential expression in normal tissues according to GTEx for OR2W1 Gene

This gene is overexpressed in Testis (43.1) and Liver (6.5).

SOURCE GeneReport for Unigene cluster for OR2W1 Gene Hs.553526

genes like me logo Genes that share expressions with OR2W1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR2W1 Gene

Orthologs for OR2W1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2W1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR2W1 35
  • 89.69 (n)
  • 87.5 (a)
-- 36
  • 88 (a)
-- 36
  • 88 (a)
(Mus musculus)
Mammalia Olfr263 35
  • 85.49 (n)
  • 85.8 (a)
Olfr263 16
Olfr1369-ps1 36
  • 85 (a)
Olfr263 36
  • 86 (a)
(Pan troglodytes)
Mammalia LOC471927 35
  • 98.96 (n)
  • 97.19 (a)
OR2W1 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr1662 35
  • 85.49 (n)
  • 84.86 (a)
(Canis familiaris)
Mammalia OR2W1 36
  • 82 (a)
(Monodelphis domestica)
Mammalia OR2W1 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
Species with no ortholog for OR2W1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2W1 Gene

Gene Tree for OR2W1 (if available)
Gene Tree for OR2W1 (if available)

Paralogs for OR2W1 Gene

Paralogs for OR2W1 Gene

(444) SIMAP similar genes for OR2W1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2W1: view

Variants for OR2W1 Gene

Sequence variations from dbSNP and Humsavar for OR2W1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
VAR_010953 -
VAR_010954 -

Structural Variations from Database of Genomic Variants (DGV) for OR2W1 Gene

Variant ID Type Subtype PubMed ID
nsv830622 CNV Gain 17160897
nsv830623 CNV Gain 17160897

Relevant External Links for OR2W1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2W1 Gene

Disorders for OR2W1 Gene

Relevant External Links for OR2W1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for OR2W1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR2W1 Gene

Publications for OR2W1 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 48
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4

Products for OR2W1 Gene

  • Addgene plasmids for OR2W1

Sources for OR2W1 Gene

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