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Aliases for OR2W1 Gene

Aliases for OR2W1 Gene

  • Olfactory Receptor Family 2 Subfamily W Member 1 2 3 5
  • Olfactory Receptor, Family 2, Subfamily W, Member 1 2 3
  • Olfactory Receptor OR6-13 3 4
  • Hs6M1-15 3 4

External Ids for OR2W1 Gene

Previous GeneCards Identifiers for OR2W1 Gene

  • GC06M029069
  • GC06M028782
  • GC06M029119
  • GC06M029011
  • GC06Mo28942
  • GC06M029059
  • GC06M029060

Summaries for OR2W1 Gene

Entrez Gene Summary for OR2W1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2W1 Gene

OR2W1 (Olfactory Receptor Family 2 Subfamily W Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2C1.

UniProtKB/Swiss-Prot for OR2W1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2W1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2W1 Gene

Genomics for OR2W1 Gene

Regulatory Elements for OR2W1 Gene

Enhancers for OR2W1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR2W1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR2W1 Gene

29,044,213 bp from pter
29,045,240 bp from pter
1,028 bases
Minus strand

Genomic View for OR2W1 Gene

Genes around OR2W1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2W1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2W1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR2W1 Gene

  • Protein details for OR2W1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2W1
    Protein Accession:
    Secondary Accessions:
    • B0S7Y5
    • Q5JNZ1
    • Q6IEU0
    • Q96R17
    • Q9GZL0
    • Q9GZL1

    Protein attributes for OR2W1 Gene

    320 amino acids
    Molecular mass:
    36101 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2W1 Gene

Proteomics data for OR2W1 Gene at MOPED

Post-translational modifications for OR2W1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2W1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2W1 Gene

Domains & Families for OR2W1 Gene

Gene Families for OR2W1 Gene

Protein Domains for OR2W1 Gene

Suggested Antigen Peptide Sequences for OR2W1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2W1: view

Function for OR2W1 Gene

Molecular function for OR2W1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 2,subfamily W,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR2W1: view

Animal Model Products

CRISPR Products

miRNA for OR2W1 Gene

miRTarBase miRNAs that target OR2W1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR2W1 Gene

Localization for OR2W1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2W1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR2W1 Gene COMPARTMENTS Subcellular localization image for OR2W1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for OR2W1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR2W1: view

Pathways & Interactions for OR2W1 Gene

genes like me logo Genes that share pathways with OR2W1: view

Pathways by source for OR2W1 Gene

1 KEGG pathway for OR2W1 Gene

Interacting Proteins for OR2W1 Gene

Gene Ontology (GO) - Biological Process for OR2W1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2W1: view

No data available for SIGNOR curated interactions for OR2W1 Gene

Drugs & Compounds for OR2W1 Gene

No Compound Related Data Available

Transcripts for OR2W1 Gene

mRNA/cDNA for OR2W1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2W1 Gene

Olfactory receptor, family 2, subfamily W, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR2W1 Gene

No ASD Table

Relevant External Links for OR2W1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2W1 Gene

mRNA expression in normal human tissues for OR2W1 Gene

mRNA differential expression in normal tissues according to GTEx for OR2W1 Gene

This gene is overexpressed in Testis (x43.1) and Liver (x6.5).

SOURCE GeneReport for Unigene cluster for OR2W1 Gene Hs.553526

genes like me logo Genes that share expression patterns with OR2W1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR2W1 Gene

Orthologs for OR2W1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2W1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR2W1 35
  • 89.69 (n)
  • 87.5 (a)
-- 36
  • 88 (a)
-- 36
  • 88 (a)
(Mus musculus)
Mammalia Olfr263 35
  • 85.49 (n)
  • 85.8 (a)
Olfr263 16
Olfr1369-ps1 36
  • 85 (a)
Olfr263 36
  • 86 (a)
(Pan troglodytes)
Mammalia LOC471927 35
  • 98.96 (n)
  • 97.19 (a)
OR2W1 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr1662 35
  • 85.49 (n)
  • 84.86 (a)
(Canis familiaris)
Mammalia OR2W1 36
  • 82 (a)
(Monodelphis domestica)
Mammalia OR2W1 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
Species with no ortholog for OR2W1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2W1 Gene

Gene Tree for OR2W1 (if available)
Gene Tree for OR2W1 (if available)

Paralogs for OR2W1 Gene

Paralogs for OR2W1 Gene

(444) SIMAP similar genes for OR2W1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2W1: view

Variants for OR2W1 Gene

Sequence variations from dbSNP and Humsavar for OR2W1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_010953 -
VAR_010954 -

Structural Variations from Database of Genomic Variants (DGV) for OR2W1 Gene

Variant ID Type Subtype PubMed ID
nsv830622 CNV Gain 17160897
nsv830623 CNV Gain 17160897

Variation tolerance for OR2W1 Gene

Residual Variation Intolerance Score: 55.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.40; 90.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR2W1 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2W1 Gene

Disorders for OR2W1 Gene

Relevant External Links for OR2W1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR2W1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2W1 Gene

Publications for OR2W1 Gene

  1. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 48 67
  2. Common variation contributes to the genetic architecture of social communication traits. (PMID: 24047820) St Pourcain B. … Smith G.D. (Mol Autism 2013) 3
  3. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3

Products for OR2W1 Gene

Sources for OR2W1 Gene