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Aliases for OR2V2 Gene

Aliases for OR2V2 Gene

  • Olfactory Receptor, Family 2, Subfamily V, Member 2 2 3
  • Olfactory Receptor OR5-3 3 4
  • Olfactory Receptor 2V3 3 4
  • OR2V3 3 4
  • Olfactory Receptor, Family 2, Subfamily V, Member 3 3
  • Olfactory Receptor 2V2 3
  • OST713 3

External Ids for OR2V2 Gene

Previous Symbols for OR2V2 Gene

  • OR2V3

Summaries for OR2V2 Gene

Entrez Gene Summary for OR2V2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2V2 Gene

OR2V2 (Olfactory Receptor, Family 2, Subfamily V, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2T1.

UniProtKB/Swiss-Prot for OR2V2 Gene

  • Odorant receptor.

Gene Wiki entry for OR2V2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2V2 Gene

Genomics for OR2V2 Gene

Genomic Location for OR2V2 Gene

Start:
181,154,943 bp from pter
End:
181,155,890 bp from pter
Size:
948 bases
Orientation:
Plus strand

Genomic View for OR2V2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2V2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2V2 Gene

Regulatory Elements for OR2V2 Gene

Proteins for OR2V2 Gene

  • Protein details for OR2V2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96R30-OR2V2_HUMAN
    Recommended name:
    Olfactory receptor 2V2
    Protein Accession:
    Q96R30
    Secondary Accessions:
    • Q6IFL6
    • Q8NGV1

    Protein attributes for OR2V2 Gene

    Size:
    315 amino acids
    Molecular mass:
    35339 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2V2 Gene

Proteomics data for OR2V2 Gene at MOPED

Post-translational modifications for OR2V2 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn6

Other Protein References for OR2V2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR2V2 Gene

Domains for OR2V2 Gene

Gene Families for OR2V2 Gene

HGNC:
  • OR2 :GPCR / Class A : Olfactory receptors

Protein Domains for OR2V2 Gene

Suggested Antigen Peptide Sequences for OR2V2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96R30

UniProtKB/Swiss-Prot:

OR2V2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q96R30
genes like me logo Genes that share domains with OR2V2: view

Function for OR2V2 Gene

Molecular function for OR2V2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2V2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2V2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR2V2 Gene

Localization for OR2V2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2V2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2V2 Gene COMPARTMENTS Subcellular localization image for OR2V2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2V2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2V2: view

Pathways for OR2V2 Gene

genes like me logo Genes that share pathways with OR2V2: view

Pathways by source for OR2V2 Gene

Interacting Proteins for OR2V2 Gene

Gene Ontology (GO) - Biological Process for OR2V2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2V2: view

Transcripts for OR2V2 Gene

mRNA/cDNA for OR2V2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2V2 Gene

No ASD Table

Relevant External Links for OR2V2 Gene

GeneLoc Exon Structure for
OR2V2
ECgene alternative splicing isoforms for
OR2V2

Expression for OR2V2 Gene

mRNA expression in normal human tissues for OR2V2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR2V2 Gene

SOURCE GeneReport for Unigene cluster for OR2V2 Gene Hs.553681

genes like me logo Genes that share expressions with OR2V2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR2V2 Gene

Orthologs for OR2V2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2V2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC471781 35
  • 99.37 (n)
  • 99.05 (a)
OR2V2 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 87 (a)
OneToMany
-- 36
  • 84 (a)
OneToMany
OR2V2 35
  • 87.2 (n)
  • 87.3 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 57 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr1396 35
  • 85.03 (n)
  • 82.8 (a)
Olfr1396 16
Olfr1396 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 74 (a)
ManyToMany
-- 36
  • 74 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr1384 35
  • 85.58 (n)
  • 85.26 (a)
Species with no ortholog for OR2V2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2V2 Gene

ENSEMBL:
Gene Tree for OR2V2 (if available)
TreeFam:
Gene Tree for OR2V2 (if available)

Paralogs for OR2V2 Gene

Selected SIMAP similar genes for OR2V2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR2V2 Gene

genes like me logo Genes that share paralogs with OR2V2: view

Variants for OR2V2 Gene

Sequence variations from dbSNP and Humsavar for OR2V2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs2259637 -- 181,153,226(-) CAAGC(A/G)GAAAA upstream-variant-2KB
rs2546423 - 181,155,604(-) GAATG(C/T)GAGCA reference, missense
rs2546424 -- 181,154,761(-) ACAGC(A/G)GTGGG upstream-variant-2KB
rs2546425 -- 181,154,614(-) TATGA(C/T)ACAGA upstream-variant-2KB
rs2546426 -- 181,154,611(-) GATAC(A/C)GAGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR2V2 Gene

Variant ID Type Subtype PubMed ID
nsv428133 CNV Gain 18775914
nsv471062 CNV Gain 18288195
dgv735n27 CNV Gain 19166990
nsv883305 CNV Gain 21882294
nsv830567 CNV Loss 17160897
nsv883307 CNV Gain 21882294
esv2436663 OTHER Inversion 19546169
esv8228 OTHER Inversion 19470904
nsv5163 CNV Loss 18451855
nsv520110 CNV Gain 19592680

Relevant External Links for OR2V2 Gene

HapMap Linkage Disequilibrium report
OR2V2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2V2 Gene

Disorders for OR2V2 Gene

Relevant External Links for OR2V2

Genetic Association Database (GAD)
OR2V2
genes like me logo Genes that share disorders with OR2V2: view

No data available for UniProtKB/Swiss-Prot for OR2V2 Gene

Publications for OR2V2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR2V2 Gene

Sources for OR2V2 Gene

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