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Aliases for OR2M2 Gene

Aliases for OR2M2 Gene

  • Olfactory Receptor Family 2 Subfamily M Member 2 2 3 5
  • Olfactory Receptor, Family 2, Subfamily M, Member 2 2 3
  • OST423 3 4
  • OR2M2Q 3

External Ids for OR2M2 Gene

Previous GeneCards Identifiers for OR2M2 Gene

  • GC00U990610
  • GC01P245216
  • GC01P244645
  • GC01P246409
  • GC01P248343

Summaries for OR2M2 Gene

Entrez Gene Summary for OR2M2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2M2 Gene

OR2M2 (Olfactory Receptor Family 2 Subfamily M Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2T1.

UniProtKB/Swiss-Prot for OR2M2 Gene

  • Odorant receptor.

Gene Wiki entry for OR2M2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2M2 Gene

Genomics for OR2M2 Gene

Regulatory Elements for OR2M2 Gene

Enhancers for OR2M2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR2M2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR2M2 Gene

248,179,986 bp from pter
248,181,029 bp from pter
1,044 bases
Plus strand

Genomic View for OR2M2 Gene

Genes around OR2M2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2M2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2M2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2M2 Gene

Proteins for OR2M2 Gene

  • Protein details for OR2M2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2M2
    Protein Accession:
    Secondary Accessions:
    • A3KFT4

    Protein attributes for OR2M2 Gene

    347 amino acids
    Molecular mass:
    39177 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2M2 Gene

Proteomics data for OR2M2 Gene at MOPED

Post-translational modifications for OR2M2 Gene

  • Glycosylation at Asn 5 and Asn 190
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2M2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2M2 Gene

Domains & Families for OR2M2 Gene

Gene Families for OR2M2 Gene

Protein Domains for OR2M2 Gene

Suggested Antigen Peptide Sequences for OR2M2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2M2: view

Function for OR2M2 Gene

Molecular function for OR2M2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR2M2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2M2 Gene

Localization for OR2M2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2M2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR2M2 Gene COMPARTMENTS Subcellular localization image for OR2M2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2M2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR2M2: view

Pathways & Interactions for OR2M2 Gene

genes like me logo Genes that share pathways with OR2M2: view

Pathways by source for OR2M2 Gene

Interacting Proteins for OR2M2 Gene

Gene Ontology (GO) - Biological Process for OR2M2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2M2: view

No data available for SIGNOR curated interactions for OR2M2 Gene

Drugs & Compounds for OR2M2 Gene

No Compound Related Data Available

Transcripts for OR2M2 Gene

mRNA/cDNA for OR2M2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2M2 Gene

No ASD Table

Relevant External Links for OR2M2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2M2 Gene

mRNA expression in normal human tissues for OR2M2 Gene

SOURCE GeneReport for Unigene cluster for OR2M2 Gene Hs.534728

genes like me logo Genes that share expression patterns with OR2M2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR2M2 Gene

Orthologs for OR2M2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2M2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC514235 35
  • 75.27 (n)
  • 71.97 (a)
-- 36
  • 74 (a)
(Pan troglodytes)
Mammalia LOC469764 35
  • 98.6 (n)
  • 97.74 (a)
(Canis familiaris)
Mammalia OR20H03 36
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 54 (a)
(Mus musculus)
Mammalia Olfr1395 36
  • 57 (a)
Species with no ortholog for OR2M2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2M2 Gene

Gene Tree for OR2M2 (if available)
Gene Tree for OR2M2 (if available)

Paralogs for OR2M2 Gene

(456) SIMAP similar genes for OR2M2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2M2: view

Variants for OR2M2 Gene

Sequence variations from dbSNP and Humsavar for OR2M2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs9435890 - 248,180,694(+) GCAAA(A/G/T)CTTTC reference, missense
rs4244171 - 248,180,643(+) ATGCT(C/G/T)GAGTT reference, missense
rs4916104 - 248,180,688(+) GTCGT(C/T)GCAAA reference, missense
rs61156873 - 248,180,245(+) CCTGT(C/G)TGGCA reference, missense
rs4345832 -- 248,178,401(+) CTCAT(A/G)CATTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR2M2 Gene

Variant ID Type Subtype PubMed ID
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv873442 CNV Gain 21882294
esv2750832 CNV Gain 17911159
dgv17e55 CNV Loss 17911159
dgv564n71 CNV Gain 21882294
dgv565n71 CNV Loss 21882294
esv2728006 CNV Deletion 23290073
nsv468861 CNV Gain 19166990
esv2728017 CNV Deletion 23290073
nsv9103 CNV Loss 18304495
dgv566n71 CNV Gain 21882294
dgv567n71 CNV Gain 21882294

Variation tolerance for OR2M2 Gene

Residual Variation Intolerance Score: 81.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.86; 48.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR2M2 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2M2 Gene

Disorders for OR2M2 Gene

Relevant External Links for OR2M2

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR2M2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2M2 Gene

Publications for OR2M2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 2 3 4 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3

Products for OR2M2 Gene

Sources for OR2M2 Gene