Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR2L13 Gene

Aliases for OR2L13 Gene

  • Olfactory Receptor, Family 2, Subfamily L, Member 13 2 3
  • Olfactory Receptor 2L14 3 4
  • OR2L14 3 4
  • Olfactory Receptor, Family 2, Subfamily L, Member 14 3
  • Olfactory Receptor 2L13 3

External Ids for OR2L13 Gene

Previous HGNC Symbols for OR2L13 Gene

  • OR2L14

Previous GeneCards Identifiers for OR2L13 Gene

  • GC00U915464
  • GC01P244426
  • GC01P246167
  • GC01P248100

Summaries for OR2L13 Gene

Entrez Gene Summary for OR2L13 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2L13 Gene

OR2L13 (Olfactory Receptor, Family 2, Subfamily L, Member 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2L2.

UniProtKB/Swiss-Prot for OR2L13 Gene

  • Odorant receptor.

Gene Wiki entry for OR2L13 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2L13 Gene

Genomics for OR2L13 Gene

Regulatory Elements for OR2L13 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for OR2L13 Gene

Start:
247,937,191 bp from pter
End:
248,100,922 bp from pter
Size:
163,732 bases
Orientation:
Plus strand

Genomic View for OR2L13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2L13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2L13 Gene

Proteins for OR2L13 Gene

  • Protein details for OR2L13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N349-OR2LD_HUMAN
    Recommended name:
    Olfactory receptor 2L13
    Protein Accession:
    Q8N349
    Secondary Accessions:
    • Q5VUR5

    Protein attributes for OR2L13 Gene

    Size:
    312 amino acids
    Molecular mass:
    35634 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2L13 Gene

Proteomics data for OR2L13 Gene at MOPED

Post-translational modifications for OR2L13 Gene

  • Glycosylation at Asn5 and Asn20
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2L13 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2L13 Gene

Domains for OR2L13 Gene

Gene Families for OR2L13 Gene

HGNC:
  • OR2 :GPCR / Class A : Olfactory receptors

Protein Domains for OR2L13 Gene

Suggested Antigen Peptide Sequences for OR2L13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N349

UniProtKB/Swiss-Prot:

OR2LD_HUMAN :
  • Q8N349
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2L13: view

Function for OR2L13 Gene

Molecular function for OR2L13 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2L13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005515 protein binding IPI 19945174
genes like me logo Genes that share ontologies with OR2L13: view

Phenotypes for OR2L13 Gene

GenomeRNAi human phenotypes for OR2L13:
genes like me logo Genes that share phenotypes with OR2L13: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2L13

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR2L13 Gene

Localization for OR2L13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2L13 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2L13 Gene COMPARTMENTS Subcellular localization image for OR2L13 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2L13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2L13: view

Pathways for OR2L13 Gene

genes like me logo Genes that share pathways with OR2L13: view

Pathways by source for OR2L13 Gene

Interacting Proteins for OR2L13 Gene

Gene Ontology (GO) - Biological Process for OR2L13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0008150 biological_process ND --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2L13: view

Transcripts for OR2L13 Gene

mRNA/cDNA for OR2L13 Gene

(8) Selected AceView cDNA sequences:
(4) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2L13 Gene

Olfactory receptor, family 2, subfamily L, member 13:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2L13

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2L13 Gene

No ASD Table

Relevant External Links for OR2L13 Gene

GeneLoc Exon Structure for
OR2L13
ECgene alternative splicing isoforms for
OR2L13

Expression for OR2L13 Gene

mRNA expression in normal human tissues for OR2L13 Gene

mRNA differential expression in normal tissues according to GTEx for OR2L13 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (6.7), Brain - Frontal Cortex (BA9) (6.2), Brain - Substantia nigra (4.7), Brain - Anterior cingulate cortex (BA24) (4.6), Brain - Hypothalamus (4.5), and Brain - Hippocampus (4.0).

SOURCE GeneReport for Unigene cluster for OR2L13 Gene Hs.372936

genes like me logo Genes that share expressions with OR2L13: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for OR2L13 Gene

Orthologs for OR2L13 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2L13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469762 35
  • 99.47 (n)
  • 99.36 (a)
OR2L13 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR2L13 35
  • 85.96 (n)
  • 87.46 (a)
OR2L13 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR2L13 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr166 35
  • 80.13 (n)
  • 85.02 (a)
Olfr166 16
Olfr166 36
  • 84 (a)
OneToMany
Olfr168 36
  • 84 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 69 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1569 35
  • 78.56 (n)
  • 84.24 (a)
Species with no ortholog for OR2L13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2L13 Gene

ENSEMBL:
Gene Tree for OR2L13 (if available)
TreeFam:
Gene Tree for OR2L13 (if available)

Paralogs for OR2L13 Gene

Paralogs for OR2L13 Gene

Selected SIMAP similar genes for OR2L13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2L13: view

Variants for OR2L13 Gene

Sequence variations from dbSNP and Humsavar for OR2L13 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1343885 -- 248,015,696(+) TTTTG(A/G)AGGCT intron-variant
rs1538198 -- 247,939,250(-) CTCTA(A/G)TGTTT intron-variant
rs1538199 -- 247,951,190(+) tacat(C/T)tttgt intron-variant
rs1538200 -- 247,951,382(+) taata(A/T)taatt intron-variant
rs1538201 -- 247,951,399(+) atcca(C/T)aagca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR2L13 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv873442 CNV Gain 21882294
dgv205e1 CNV Complex 17122850
nsv873443 CNV Gain 21882294
esv2750832 CNV Gain 17911159
esv2727929 CNV Deletion 23290073
esv29107 CNV Gain 19812545
nsv873444 CNV Gain 21882294
nsv9080 CNV Gain 18304495
nsv508070 CNV Loss 20534489
nsv873445 CNV Loss 21882294
nsv9091 CNV Loss 18304495
esv2663706 CNV Deletion 23128226
dgv75e201 CNV Deletion 23290073
nsv827786 CNV Loss 20364138
nsv827797 CNV Loss 20364138
dgv76e201 CNV Deletion 23290073
esv29477 CNV Loss 19812545
dgv111e199 CNV Deletion 23128226
esv2613716 CNV Deletion 19546169
esv2035728 CNV Deletion 18987734
esv3861 CNV Deletion 18987735
esv2727984 CNV Deletion 23290073
esv267534 CNV Insertion 20981092
dgv17e55 CNV Loss 17911159
dgv564n71 CNV Gain 21882294
dgv565n71 CNV Loss 21882294
esv2727995 CNV Deletion 23290073
esv2728006 CNV Deletion 23290073
nsv468861 CNV Gain 19166990

Relevant External Links for OR2L13 Gene

HapMap Linkage Disequilibrium report
OR2L13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2L13 Gene

Disorders for OR2L13 Gene

Relevant External Links for OR2L13

Genetic Association Database (GAD)
OR2L13
Human Genome Epidemiology (HuGE) Navigator
OR2L13
genes like me logo Genes that share disorders with OR2L13: view

No data available for UniProtKB/Swiss-Prot for OR2L13 Gene

Publications for OR2L13 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for OR2L13 Gene

Sources for OR2L13 Gene

Back to Top

Content