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Aliases for OR2J1 Gene

Aliases for OR2J1 Gene

  • Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 Pseudogene 2 3
  • Hs6M1-4 3 4
  • OR2J1P 3 4
  • OR6-5 3 4
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 2
  • Olfactory Receptor OR6-15 3
  • Olfactory Receptor 6-5 4
  • DJ80I19.2 3
  • 6M1-4P 3
  • OR6-15 3

External Ids for OR2J1 Gene

Previous Symbols for OR2J1 Gene

  • OR2J1P

Summaries for OR2J1 Gene

Entrez Gene Summary for OR2J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2J1 Gene

OR2J1 (Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2C1.

UniProtKB/Swiss-Prot for OR2J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2J1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2J1 Gene

Genomics for OR2J1 Gene

Genomic Location for OR2J1 Gene

Start:
29,100,609 bp from pter
End:
29,101,881 bp from pter
Size:
1,273 bases
Orientation:
Plus strand

Genomic View for OR2J1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for OR2J1 Gene

Proteins for OR2J1 Gene

  • Protein details for OR2J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZK6-OR2J1_HUMAN
    Recommended name:
    Olfactory receptor 2J1
    Protein Accession:
    Q9GZK6
    Secondary Accessions:
    • A2AAS1
    • B0V1T2
    • Q9GZK1

    Protein attributes for OR2J1 Gene

    Size:
    312 amino acids
    Molecular mass:
    35454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2J1 Gene

Proteomics data for OR2J1 Gene at MOPED

Post-translational modifications for OR2J1 Gene

Other Protein References for OR2J1 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for OR2J1 Gene

Domains for OR2J1 Gene

Gene Families for OR2J1 Gene

HGNC:
  • OR2 :GPCR / Class A : Olfactory receptors

Protein Domains for OR2J1 Gene

UniProtKB/Swiss-Prot:

OR2J1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9GZK6
genes like me logo Genes that share domains with OR2J1: view

Function for OR2J1 Gene

Molecular function for OR2J1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2J1: view

miRNA for OR2J1 Gene

miRTarBase miRNAs that target OR2J1

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR2J1 Gene

Localization for OR2J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2J1 Gene COMPARTMENTS Subcellular localization image for OR2J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2J1: view

Pathways for OR2J1 Gene

genes like me logo Genes that share pathways with OR2J1: view

Pathways by source for OR2J1 Gene

Interacting Proteins for OR2J1 Gene

Gene Ontology (GO) - Biological Process for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2J1: view

Transcripts for OR2J1 Gene

mRNA/cDNA for OR2J1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2J1 Gene

No ASD Table

Relevant External Links for OR2J1 Gene

GeneLoc Exon Structure for
OR2J1
ECgene alternative splicing isoforms for
OR2J1

Expression for OR2J1 Gene

mRNA expression in normal human tissues for OR2J1 Gene

genes like me logo Genes that share expressions with OR2J1: view

Orthologs for OR2J1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2J1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR2J1 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 87 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr137 37
  • 80 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 59 (a)
OneToMany
Species with no ortholog for OR2J1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2J1 Gene

ENSEMBL:
Gene Tree for OR2J1 (if available)
TreeFam:
Gene Tree for OR2J1 (if available)

Paralogs for OR2J1 Gene

Paralogs for OR2J1 Gene

Selected SIMAP similar genes for OR2J1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2J1: view

Variants for OR2J1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR2J1 Gene

Q9GZK6-OR2J1_HUMAN
A stop codon in the gene coding for this protein at position Gln-194 is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans

Sequence variations from dbSNP and Humsavar for OR2J1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
VAR_019066 -

Relevant External Links for OR2J1 Gene

HapMap Linkage Disequilibrium report
OR2J1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR2J1 Gene

Disorders for OR2J1 Gene

No disorders were found for OR2J1 Gene.

No data available for UniProtKB/Swiss-Prot for OR2J1 Gene

Publications for OR2J1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  2. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 4
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4

Products for OR2J1 Gene

Sources for OR2J1 Gene

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