OR2J1 Gene
protein-coding GIFtS : 28 GCID: GC06 P029069
Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene) olfactory receptor, family 2, subfamily J, member 1 pseudogene,... OR2J1P )
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Aliasesfor OR2J1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene) 1 2 OR6-152 OR2J1P1 2 3 dJ80I19.22 OR6-52 3 hs6M1-42 Olfactory Receptor, Family 2, Subfamily J, Member 11 Hs6M1-43 Olfactory Receptor, Family 2, Subfamily J, Member 1 Pseudogene1 Olfactory Receptor 6-53 6M1-4P2
Export aliases for OR2J1 gene to outside databases Previous GC identifers: GC06U900570 GC06P029176 GC06P028876 GC06Pi29069
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Summariesfor OR2J1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for OR2J1 Gene: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. (provided by RefSeq, Jul 2008) GeneCards Summary for OR2J1 Gene: OR2J1 (olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)) is a protein-coding gene. Diseases associated with OR2J1 include neuronitis related super-pathways are Signaling by GPCR and Olfactory transduction . GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity . An important paralog of this gene is OR2W1 . UniProtKB/Swiss-Prot: OR2J1_HUMAN, Q9GZK6 Function : Odorant receptor (Potential)Gene Wiki entry for OR2J1 Gene
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Genomic Viewsfor OR2J1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for OR2J1 Other transcription factors Search SABiosciences Chromatin IP Primers for OR2J1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR2J1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p22.2-p21.31 OR2J1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 6 GeneLoc Exon Structure
GeneLoc location for GC06P029069: view genomic region
(about GC identifiers )
Start: 29,068,386 bp from pter End:
29,069,658 bp from pter
Size: 1,273 bases Orientation:
plus strand
6/7 alternative locations (see all 7 ): Chr 6+,NT_167246 372,128-373,063 Chr 6+,NT_167247 372,265-373,200 Chr 6+,NT_113891.2 587,595-588,530 Chr 6+,NT_167248 372,126-373,061 Chr 6+,NT_167249 409,611-410,546 Chr 6+,NT_167245 372,136-373,071
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Proteinsfor OR2J1 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: OR2J1_HUMAN, Q9GZK6 See
protein sequence )Recommended Name: Size : 312 amino acids; 35454 DaSubcellular location : Cell membrane; Multi-pass membrane proteinSecondary accessions : A2AAS1 B0V1T2 Q9GZK1Explore the universe of human proteins at neXtProt for OR2J1: NX_Q9GZK6 Explore proteomics data for OR2J1 at MOPED OR2J1 Protein expression data from MOPED1 2 3 : About this image
ENSEMBL proteins: ENSP00000366376 Reactome Protein details: Q9GZK6 Human Recombinant Protein Products for OR2J1: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005886 plasma membrane
TAS -- GO:0016021 integral to membrane
IEA --
About GeneDecksing OR2J1 Antibody Products: Assay Products for OR2J1:
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Protein
Domains /for OR2J1 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section HGNC Gene Families: OR2: GPCR / Class A : Olfactory receptors 3 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry Q9GZK6 ProtoNet protein and cluster: Q9GZK6
1 Blocks protein domain : IPB000725 UniProtKB/Swiss-Prot: OR2J1_HUMAN, Q9GZK6 Similarity : Belongs to the G-protein coupled receptor 1 familyAbout GeneDecksing
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Functionfor OR2J1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: OR2J1_HUMAN, Q9GZK6 Function : Odorant receptor (Potential)
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0004930 G-protein coupled receptor activity
IEA -- GO:0004984 olfactory receptor activity
IEA --
About GeneDecksing Animal Models: In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR2J1
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Pathways & Interactionsfor OR2J1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for OR2J1 About See pathways by source SuperPath Contained pathways About 1 Signaling by GPCR 2 Olfactory transduction 3 Class A/1 (Rhodopsin-like receptors)
Pathways by source See SuperPaths Show all pathways 1 4 About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR2J1 Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007186 G-protein coupled receptor signaling pathway
-- --
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Drugs & Compoundsfor OR2J1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for OR2J1 OR2J1
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Transcriptsfor OR2J1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000377171 GeneLoc Exon Structure
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Expression for OR2J1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section OR2J1 expression in normal human tissues
(normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
See OR2J1 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for OR2J1 Primer Browse OriGene qPCR Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat OR2J1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR2J1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR2J1 In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR2J1
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Orthologsfor OR2J1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
ENSEMBL Gene Tree for OR2J1 (if available)TreeFam Gene Tree for OR2J1 (if available)
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Paralogsfor OR2J1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for OR2J1 gene OR2W1 2 OR2J2 2 OR2B11 2 OR2H2 2 OR2B2 2 OR2B3 2 OR2H1 2 OR2C1 2 OR2Y1 2 OR2G2 2 OR2B6 2 OR2W3 2 OR2J3 2 OR2G3 2 OR2C3 2 OR2G6 2 18/453 SIMAP similar genes for OR2J1 using alignment to 1 protein entry: OR2J1_HUMAN (see all similar genes ):OR2J2 OR2J3 OR2J4P OR2W6P OLFR 42A OR2B2 OR2C3 6M1-16 OR2B6 OR2C1 OR2G3 OR2H1 OR2Y1 OR2B11 OR2B8P OR2G6 OR2W1 OR2W3 About GeneDecksing
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Genomic Variantsfor OR2J1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section UniProtKB/Swiss-Prot: OR2J1_HUMAN, Q9GZK6 Polymorphism : A stop codon in the gene coding for this protein at position Gln-194 is responsible for functionaldiversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 6 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for OR2J1 (29068386 - 29069658 bp)
Structural Variations Database of Genomic Variants (DGV) variations for OR2J1: -- Human Gene Mutation Database (HGMD) : OR2J1 SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor OR2J1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing 2 : About MalaCards neuronitis Export disorders for OR2J1 gene to outside databases
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Publicationsfor OR2J1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for OR2J1 gene integrated from 9 sources :(articles sorted by number of sources associating them with OR2J1) Utopia : connect your pdf to the dynamic
The human olfactory receptor gene family. (PubMed id 14983052) 1 (2004) The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404) 2 (2003) Different noses for different people. (PubMed id 12730696) 2 (2003) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 (2000)
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External Searches for OR2J1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing OR2J1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing OR2J1 gene
(According to HUGE )
About This Section --
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Specialized Databases showing OR2J1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for OR2J1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for OR2J1 gene: OR2J1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor OR2J1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OR2J1 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OR2J1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR2J1 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR2J1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR2J1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR2J1
Search Tocris compounds for OR2J1
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR2J1
Search ThermoFisher Antibodies for OR2J1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat OR2J1
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