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OR2J1 Gene(Protein Coding)

Olfactory Receptor Family 2 Subfamily J Member 1 (Gene/Pseudogene)

GCID:
GC06P029100
GIFtS:
24
Genes Participants
UDN Logo

Aliases for OR2J1 Gene

Aliases for OR2J1 Gene

  • Olfactory Receptor Family 2 Subfamily J Member 1 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 Pseudogene 2 3
  • Hs6M1-4 3 4
  • OR2J1P 3 4
  • OR6-5 3 4
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 2
  • Olfactory Receptor OR6-15 3
  • Olfactory Receptor 6-5 4
  • DJ80I19.2 3
  • 6M1-4P 3
  • OR6-15 3

External Ids for OR2J1 Gene

Previous HGNC Symbols for OR2J1 Gene

  • OR2J1P

Previous GeneCards Identifiers for OR2J1 Gene

  • GC06U900570
  • GC06P029176
  • GC06P029069
  • GC06P028876
  • GC06Pi29069
  • GC06P029070

Summaries for OR2J1 Gene

Entrez Gene Summary for OR2J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2J1 Gene

OR2J1 (Olfactory Receptor Family 2 Subfamily J Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2C1.

UniProtKB/Swiss-Prot for OR2J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2J1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2J1 Gene

Genomics for OR2J1 Gene

Products:

  1. Regulatory Element

Genomic Location for OR2J1 Gene

Chromosome:
6
Start:
29,100,609 bp from pter
End:
29,101,881 bp from pter
Size:
1,273 bases
Orientation:
Plus strand

Genomic View for OR2J1 Gene

Genes around OR2J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2J1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for OR2J1 Gene

No data available for Regulatory Elements for OR2J1 Gene

Proteins for OR2J1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for OR2J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZK6-OR2J1_HUMAN
    Recommended name:
    Olfactory receptor 2J1
    Protein Accession:
    Q9GZK6
    Secondary Accessions:
    • A2AAS1
    • B0V1T2
    • Q9GZK1

    Protein attributes for OR2J1 Gene

    Size:
    312 amino acids
    Molecular mass:
    35454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2J1 Gene

Proteomics data for OR2J1 Gene at MOPED

Post-translational modifications for OR2J1 Gene

Other Protein References for OR2J1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for OR2J1 Gene

Domains & Families for OR2J1 Gene

Gene Families for OR2J1 Gene

HGNC:

Protein Domains for OR2J1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for OR2J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9GZK6

UniProtKB/Swiss-Prot:

OR2J1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2J1: view

Function for OR2J1 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Molecular function for OR2J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR2J1 Gene

GenomeRNAi human phenotypes for OR2J1:
genes like me logo Genes that share phenotypes with OR2J1: view

miRNA for OR2J1 Gene

miRTarBase miRNAs that target OR2J1

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR2J1 Gene

Localization for OR2J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2J1 Gene COMPARTMENTS Subcellular localization image for OR2J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR2J1: view

Pathways & Interactions for OR2J1 Gene

genes like me logo Genes that share pathways with OR2J1: view

Pathways by source for OR2J1 Gene

1 BioSystems pathway for OR2J1 Gene

Interacting Proteins for OR2J1 Gene

Gene Ontology (GO) - Biological Process for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2J1: view

No data available for SIGNOR curated interactions for OR2J1 Gene

Drugs & Compounds for OR2J1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for OR2J1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for OR2J1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2J1 Gene

No ASD Table

Relevant External Links for OR2J1 Gene

GeneLoc Exon Structure for
OR2J1
ECgene alternative splicing isoforms for
OR2J1

Expression for OR2J1 Gene

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  1. Primer

mRNA expression in normal human tissues for OR2J1 Gene

mRNA expression in normal human tissues for OR2J1 Gene
mRNA expression by GTEx for OR2J1 Gene
genes like me logo Genes that share expression patterns with OR2J1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR2J1 Gene

Orthologs for OR2J1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2J1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia -- 36
  • 87 (a)
 OneToMany
mouse
(Mus musculus)
 Mammalia Olfr137 36
  • 80 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 36
  • 59 (a)
 OneToMany
chimpanzee
(Pan troglodytes)
 Mammalia OR2J1 36
  • 98 (a)
 OneToOne
Species with no ortholog for OR2J1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2J1 Gene

ENSEMBL:
Gene Tree for OR2J1 (if available)
TreeFam:
Gene Tree for OR2J1 (if available)

Paralogs for OR2J1 Gene

Paralogs for OR2J1 Gene

(452) SIMAP similar genes for OR2J1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2J1: view

Variants for OR2J1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR2J1 Gene

OR2J1_HUMAN-Q9GZK6
A stop codon in the gene coding for this protein at position Gln-194 is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans.

Sequence variations from dbSNP and Humsavar for OR2J1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_019066 -

Variation tolerance for OR2J1 Gene

Gene Damage Index Score: 19.95; 98.99% of all genes are more intolerant (likely to be disease-causing)

No data available for Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for OR2J1 Gene

Disorders for OR2J1 Gene

No disorders were found for OR2J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR2J1 Gene

Publications for OR2J1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 67

Products for OR2J1 Gene

Sources for OR2J1 Gene

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