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Aliases for OR2G2 Gene

Aliases for OR2G2 Gene

  • Olfactory Receptor, Family 2, Subfamily G, Member 2 2 3
  • Olfactory Receptor, Family 2, Subfamily G, Member 2 Pseudogene 2 3
  • Olfactory Receptor OR1-32 3 4
  • OR1-32 3

External Ids for OR2G2 Gene

Previous GeneCards Identifiers for OR2G2 Gene

  • GC01U990413
  • GC01P244077
  • GC01P245818
  • GC01P247751

Summaries for OR2G2 Gene

Entrez Gene Summary for OR2G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2G2 Gene

OR2G2 (Olfactory Receptor, Family 2, Subfamily G, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2C1.

UniProtKB/Swiss-Prot for OR2G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR2G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2G2 Gene

Genomics for OR2G2 Gene

Regulatory Elements for OR2G2 Gene

Genomic Location for OR2G2 Gene

Chromosome:
1
Start:
247,588,360 bp from pter
End:
247,589,313 bp from pter
Size:
954 bases
Orientation:
Plus strand

Genomic View for OR2G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2G2 Gene

Proteins for OR2G2 Gene

  • Protein details for OR2G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGZ5-OR2G2_HUMAN
    Recommended name:
    Olfactory receptor 2G2
    Protein Accession:
    Q8NGZ5
    Secondary Accessions:
    • Q5JQT2
    • Q6IEZ0

    Protein attributes for OR2G2 Gene

    Size:
    317 amino acids
    Molecular mass:
    35559 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04870.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR2G2 Gene

Proteomics data for OR2G2 Gene at MOPED

Post-translational modifications for OR2G2 Gene

  • Glycosylation at Asn 8
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2G2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2G2 Gene

Domains & Families for OR2G2 Gene

Gene Families for OR2G2 Gene

Protein Domains for OR2G2 Gene

Suggested Antigen Peptide Sequences for OR2G2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGZ5

UniProtKB/Swiss-Prot:

OR2G2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2G2: view

Function for OR2G2 Gene

Molecular function for OR2G2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2G2: view

Phenotypes for OR2G2 Gene

genes like me logo Genes that share phenotypes with OR2G2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2G2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2G2 Gene

Localization for OR2G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2G2 Gene COMPARTMENTS Subcellular localization image for OR2G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2G2: view

Pathways & Interactions for OR2G2 Gene

genes like me logo Genes that share pathways with OR2G2: view

Pathways by source for OR2G2 Gene

Interacting Proteins for OR2G2 Gene

Gene Ontology (GO) - Biological Process for OR2G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2G2: view

No data available for SIGNOR curated interactions for OR2G2 Gene

Drugs & Compounds for OR2G2 Gene

No Compound Related Data Available

Transcripts for OR2G2 Gene

mRNA/cDNA for OR2G2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2G2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2G2 Gene

No ASD Table

Relevant External Links for OR2G2 Gene

GeneLoc Exon Structure for
OR2G2
ECgene alternative splicing isoforms for
OR2G2

Expression for OR2G2 Gene

mRNA expression in normal human tissues for OR2G2 Gene

SOURCE GeneReport for Unigene cluster for OR2G2 Gene Hs.690208

genes like me logo Genes that share expression patterns with OR2G2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR2G2 Gene

Orthologs for OR2G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2G2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC508626 35
  • 83.23 (n)
  • 81.73 (a)
OR2G2 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC469747 35
  • 97.37 (n)
  • 94.95 (a)
OR2G2 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 62 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr131 36
  • 50 (a)
ManyToMany
Species with no ortholog for OR2G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2G2 Gene

ENSEMBL:
Gene Tree for OR2G2 (if available)
TreeFam:
Gene Tree for OR2G2 (if available)

Paralogs for OR2G2 Gene

Paralogs for OR2G2 Gene

(439) SIMAP similar genes for OR2G2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2G2: view

Variants for OR2G2 Gene

Sequence variations from dbSNP and Humsavar for OR2G2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_034174 -
VAR_034175 -
VAR_034176 -
VAR_034177 -

Structural Variations from Database of Genomic Variants (DGV) for OR2G2 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv270397 CNV Insertion 20981092

Variation tolerance for OR2G2 Gene

Residual Variation Intolerance Score: 64.96% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.25; 95.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR2G2 Gene

HapMap Linkage Disequilibrium report
OR2G2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2G2 Gene

Disorders for OR2G2 Gene

Relevant External Links for OR2G2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR2G2
genes like me logo Genes that share disorders with OR2G2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2G2 Gene

Publications for OR2G2 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 67

Products for OR2G2 Gene

Sources for OR2G2 Gene

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