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Aliases for OR2AG2 Gene

Aliases for OR2AG2 Gene

  • Olfactory Receptor Family 2 Subfamily AG Member 2 2 3 5
  • OR2AG2P 3 4
  • Olfactory Receptor, Family 2, Subfamily AG, Member 2 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily AG, Member 2 2
  • Olfactory Receptor OR11-76 Pseudogene 3
  • OR11-76 3

External Ids for OR2AG2 Gene

Previous HGNC Symbols for OR2AG2 Gene

  • OR2AG2P

Previous GeneCards Identifiers for OR2AG2 Gene

  • GC11M006754
  • GC11M006745
  • GC11M006790

Summaries for OR2AG2 Gene

Entrez Gene Summary for OR2AG2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2AG2 Gene

OR2AG2 (Olfactory Receptor Family 2 Subfamily AG Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2T1.

UniProtKB/Swiss-Prot for OR2AG2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2AG2 Gene

Genomics for OR2AG2 Gene

Regulatory Elements for OR2AG2 Gene

Enhancers for OR2AG2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR2AG2 on UCSC Golden Path with GeneCards custom track

Promoters for OR2AG2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around OR2AG2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR2AG2 Gene

6,767,345 bp from pter
6,926,426 bp from pter
159,082 bases
Minus strand

Genomic View for OR2AG2 Gene

Genes around OR2AG2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2AG2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2AG2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2AG2 Gene

Proteins for OR2AG2 Gene

  • Protein details for OR2AG2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2AG2
    Protein Accession:

    Protein attributes for OR2AG2 Gene

    316 amino acids
    Molecular mass:
    35270 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2AG2 Gene

Proteomics data for OR2AG2 Gene at MOPED

Post-translational modifications for OR2AG2 Gene

  • Glycosylation at Asn 5 and Asn 19
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2AG2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2AG2 Gene

Domains & Families for OR2AG2 Gene

Gene Families for OR2AG2 Gene

Protein Domains for OR2AG2 Gene

Suggested Antigen Peptide Sequences for OR2AG2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2AG2: view

Function for OR2AG2 Gene

Molecular function for OR2AG2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR2AG2 Gene

genes like me logo Genes that share phenotypes with OR2AG2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2AG2 Gene

Localization for OR2AG2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2AG2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR2AG2 Gene COMPARTMENTS Subcellular localization image for OR2AG2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2AG2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR2AG2: view

Pathways & Interactions for OR2AG2 Gene

genes like me logo Genes that share pathways with OR2AG2: view

Pathways by source for OR2AG2 Gene

Interacting Proteins for OR2AG2 Gene

Gene Ontology (GO) - Biological Process for OR2AG2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2AG2: view

No data available for SIGNOR curated interactions for OR2AG2 Gene

Drugs & Compounds for OR2AG2 Gene

No Compound Related Data Available

Transcripts for OR2AG2 Gene

mRNA/cDNA for OR2AG2 Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2AG2 Gene

Olfactory receptor, family 2, subfamily AG, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR2AG2 Gene

No ASD Table

Relevant External Links for OR2AG2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2AG2 Gene

mRNA expression in normal human tissues for OR2AG2 Gene

mRNA differential expression in normal tissues according to GTEx for OR2AG2 Gene

This gene is overexpressed in Testis (x4.5), Brain - Nucleus accumbens (basal ganglia) (x4.1), and Brain - Frontal Cortex (BA9) (x4.0).

SOURCE GeneReport for Unigene cluster for OR2AG2 Gene Hs.534614

genes like me logo Genes that share expression patterns with OR2AG2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR2AG2 Gene

Orthologs for OR2AG2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2AG2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR2AG1 35
  • 83.76 (n)
  • 82.48 (a)
-- 36
  • 81 (a)
-- 36
  • 83 (a)
-- 36
  • 82 (a)
(Canis familiaris)
Mammalia cOR2AG1 35
  • 84.23 (n)
  • 81.9 (a)
-- 36
  • 82 (a)
(Mus musculus)
Mammalia Olfr701 35
  • 81.75 (n)
  • 80.38 (a)
Olfr701 16
Olfr693 36
  • 73 (a)
Olfr694 36
  • 77 (a)
Olfr695 36
  • 75 (a)
Olfr697 36
  • 73 (a)
Olfr698 36
  • 77 (a)
Olfr699 36
  • 72 (a)
Olfr700 36
  • 78 (a)
Olfr701 36
  • 80 (a)
Olfr703 36
  • 74 (a)
Olfr704 36
  • 75 (a)
Olfr705 36
  • 80 (a)
Olfr706 36
  • 82 (a)
(Pan troglodytes)
Mammalia LOC466416 35
  • 98.63 (n)
  • 98.1 (a)
OR2AG2 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Olr210 35
  • 80.59 (n)
  • 79.75 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
-- 36
  • 70 (a)
-- 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 49 (a)
Species with no ortholog for OR2AG2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2AG2 Gene

Gene Tree for OR2AG2 (if available)
Gene Tree for OR2AG2 (if available)

Paralogs for OR2AG2 Gene

(451) SIMAP similar genes for OR2AG2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR2AG2: view

Variants for OR2AG2 Gene

Sequence variations from dbSNP and Humsavar for OR2AG2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs7102536 - 6,768,875(+) TAGCA(C/T)AGAGC reference, missense
rs10839616 - 6,768,797(+) GGAGC(A/C/G/T)GGGCT reference, missense
rs11828782 - 6,768,698(+) CTCTG(A/C/T)GCAGA reference, missense
rs7924459 - 6,768,063(+) GGCCC(C/G)CATGA reference, missense
rs519943 -- 6,774,668(-) CAAAA(C/T)TTCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR2AG2 Gene

Variant ID Type Subtype PubMed ID
nsv832060 CNV Gain 17160897
nsv467701 CNV Loss 19166990

Variation tolerance for OR2AG2 Gene

Residual Variation Intolerance Score: 96.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.09; 87.67% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR2AG2 Gene

Disorders for OR2AG2 Gene

Relevant External Links for OR2AG2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR2AG2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2AG2 Gene

Publications for OR2AG2 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 67
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR2AG2 Gene

Sources for OR2AG2 Gene