Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR2AG1 Gene

Aliases for OR2AG1 Gene

  • Olfactory Receptor, Family 2, Subfamily AG, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor OR11-79 3 4
  • Olfactory Receptor 2AG3 3 4
  • OR2AG3 3 4
  • Olfactory Receptor, Family 2, Subfamily AG, Member 3 3
  • Olfactory Receptor 2AG1 3
  • HT3 Olfactory Receptor 3
  • OR11-79 3
  • HT3 4

External Ids for OR2AG1 Gene

Previous Symbols for OR2AG1 Gene

  • OR2AG3

Summaries for OR2AG1 Gene

Entrez Gene Summary for OR2AG1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2AG1 Gene

OR2AG1 (Olfactory Receptor, Family 2, Subfamily AG, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR2AG1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2AG1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2AG1 Gene

Genomics for OR2AG1 Gene

Genomic Location for OR2AG1 Gene

Start:
6,785,017 bp from pter
End:
6,786,014 bp from pter
Size:
998 bases
Orientation:
Plus strand

Genomic View for OR2AG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2AG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2AG1 Gene

Regulatory Elements for OR2AG1 Gene

Proteins for OR2AG1 Gene

  • Protein details for OR2AG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H205-O2AG1_HUMAN
    Recommended name:
    Olfactory receptor 2AG1
    Protein Accession:
    Q9H205
    Secondary Accessions:
    • B9EKV7
    • Q6IFG7
    • Q96R26

    Protein attributes for OR2AG1 Gene

    Size:
    316 amino acids
    Molecular mass:
    35270 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2AG1 Gene

Proteomics data for OR2AG1 Gene at MOPED

Post-translational modifications for OR2AG1 Gene

Other Protein References for OR2AG1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR2AG1 Gene

Domains for OR2AG1 Gene

Gene Families for OR2AG1 Gene

HGNC:
  • OR2 :GPCR / Class A : Olfactory receptors

Protein Domains for OR2AG1 Gene

UniProtKB/Swiss-Prot:

O2AG1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9H205
genes like me logo Genes that share domains with OR2AG1: view

Function for OR2AG1 Gene

Molecular function for OR2AG1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005515 protein binding IPI 19909339
genes like me logo Genes that share ontologies with OR2AG1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR2AG1 Gene

Localization for OR2AG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2AG1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR2AG1 Gene COMPARTMENTS Subcellular localization image for OR2AG1 gene
Compartment Confidence
plasma membrane 5
nucleus 1

Gene Ontology (GO) - Cellular Components for OR2AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2AG1: view

Pathways for OR2AG1 Gene

genes like me logo Genes that share pathways with OR2AG1: view

Pathways by source for OR2AG1 Gene

1 BioSystems pathway for OR2AG1 Gene
1 KEGG pathway for OR2AG1 Gene

Gene Ontology (GO) - Biological Process for OR2AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2AG1: view

Transcripts for OR2AG1 Gene

mRNA/cDNA for OR2AG1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2AG1 Gene

No ASD Table

Relevant External Links for OR2AG1 Gene

GeneLoc Exon Structure for
OR2AG1
ECgene alternative splicing isoforms for
OR2AG1

Expression for OR2AG1 Gene

mRNA expression in normal human tissues for OR2AG1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR2AG1 Gene

SOURCE GeneReport for Unigene cluster for OR2AG1 Gene Hs.553608

genes like me logo Genes that share expressions with OR2AG1: view

Orthologs for OR2AG1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2AG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466417 36
  • 98.73 (n)
  • 97.78 (a)
cow
(Bos Taurus)
Mammalia LOC100125776 36
  • 86.09 (n)
  • 81.21 (a)
mouse
(Mus musculus)
Mammalia Olfr705 36
  • 83.12 (n)
  • 82.59 (a)
Olfr705 16
rat
(Rattus norvegicus)
Mammalia Olr217 36
  • 82.59 (n)
  • 83.23 (a)
Species with no ortholog for OR2AG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2AG1 Gene

ENSEMBL:
Gene Tree for OR2AG1 (if available)
TreeFam:
Gene Tree for OR2AG1 (if available)

Paralogs for OR2AG1 Gene

Selected SIMAP similar genes for OR2AG1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2AG1: view

No data available for Paralogs for OR2AG1 Gene

Variants for OR2AG1 Gene

Sequence variations from dbSNP and Humsavar for OR2AG1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs471312 -- 6,783,753(-) GTTAC(C/T)GGGAG upstream-variant-2KB
rs495707 -- 6,786,237(-) TACCT(A/T)CCTGG downstream-variant-500B
rs497681 -- 6,786,012(-) GAATT(C/T)TGGAA utr-variant-3-prime
rs656243 -- 6,783,968(-) TGAAC(A/G)TGCAG upstream-variant-2KB
rs659784 -- 6,783,164(-) CTCAC(A/G)CCTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR2AG1 Gene

Variant ID Type Subtype PubMed ID
nsv832060 CNV Gain 17160897
nsv467701 CNV Loss 19166990

Relevant External Links for OR2AG1 Gene

HapMap Linkage Disequilibrium report
OR2AG1

Disorders for OR2AG1 Gene

(1) University of Copenhagen DISEASES for OR2AG1 Gene

genes like me logo Genes that share disorders with OR2AG1: view

No data available for UniProtKB/Swiss-Prot for OR2AG1 Gene

Publications for OR2AG1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Genomic analysis of orthologous mouse and human olfactory receptor loci. (PMID: 11416212) Lane R.P. … Trask B.J. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins. (PMID: 16565291) Neuhaus E.M. … Hatt H. (Chem. Senses 2006) 3

Products for OR2AG1 Gene

  • antibodies-online proteins for OR2AG1
  • antibodies-online antibodies for OR2AG1
  • antibodies-online kits for OR2AG1

Sources for OR2AG1 Gene

Back to Top

Content