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Aliases for OR2A7 Gene

Aliases for OR2A7 Gene

  • Olfactory Receptor, Family 2, Subfamily A, Member 7 2 3
  • Olfactory Receptor OR7-18 3 4
  • Olfactory Receptor, Family 2, Subfamily A, Member 21 3
  • Olfactory Receptor OR7-20 3
  • Olfactory Receptor 2A7 3
  • HSDJ0798C17 3
  • OR2A21 3

External Ids for OR2A7 Gene

Previous GeneCards Identifiers for OR2A7 Gene

  • GC07U990172
  • GC07M143393
  • GC07M143587
  • GC07M143588
  • GC07M143589
  • GC07M143590
  • GC07M143591
  • GC07M143955

Summaries for OR2A7 Gene

Entrez Gene Summary for OR2A7 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2A7 Gene

OR2A7 (Olfactory Receptor, Family 2, Subfamily A, Member 7) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2A42.

UniProtKB/Swiss-Prot for OR2A7 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2A7 Gene

Genomics for OR2A7 Gene

Regulatory Elements for OR2A7 Gene

Genomic Location for OR2A7 Gene

144,258,607 bp from pter
144,259,722 bp from pter
1,116 bases
Minus strand

Genomic View for OR2A7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR2A7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2A7 Gene

Proteins for OR2A7 Gene

  • Protein details for OR2A7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2A7
    Protein Accession:
    Secondary Accessions:
    • B2RN57
    • Q6IFP4

    Protein attributes for OR2A7 Gene

    310 amino acids
    Molecular mass:
    34742 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2A7 Gene

Proteomics data for OR2A7 Gene at MOPED

Post-translational modifications for OR2A7 Gene

  • Glycosylation at Asn4
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2A7 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2A7 Gene

Domains for OR2A7 Gene

Gene Families for OR2A7 Gene

Protein Domains for OR2A7 Gene

Suggested Antigen Peptide Sequences for OR2A7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2A7: view

Function for OR2A7 Gene

Molecular function for OR2A7 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity --
GO:0004984 olfactory receptor activity IEA --
GO:0008527 taste receptor activity IBA --
genes like me logo Genes that share ontologies with OR2A7: view

Phenotypes for OR2A7 Gene

GenomeRNAi human phenotypes for OR2A7:
genes like me logo Genes that share phenotypes with OR2A7: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2A7

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR2A7 Gene

Localization for OR2A7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2A7 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR2A7 Gene COMPARTMENTS Subcellular localization image for OR2A7 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2A7: view

Pathways for OR2A7 Gene

genes like me logo Genes that share pathways with OR2A7: view

Pathways by source for OR2A7 Gene

Interacting Proteins for OR2A7 Gene

Gene Ontology (GO) - Biological Process for OR2A7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
GO:0050912 detection of chemical stimulus involved in sensory perception of taste IBA --
genes like me logo Genes that share ontologies with OR2A7: view

Transcripts for OR2A7 Gene

mRNA/cDNA for OR2A7 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(176) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2A7 Gene

Olfactory receptor, family 2, subfamily A, member 7:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR2A7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2A7 Gene

No ASD Table

Relevant External Links for OR2A7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2A7 Gene

mRNA expression in normal human tissues for OR2A7 Gene

mRNA differential expression in normal tissues according to GTEx for OR2A7 Gene

This gene is overexpressed in Thyroid (4.3) and Skin - Sun Exposed (Lower leg) (4.1).

SOURCE GeneReport for Unigene cluster for OR2A7 Gene Hs.658609

genes like me logo Genes that share expressions with OR2A7: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR2A7 Gene

Orthologs for OR2A7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR2A7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC507423 35
  • 84.69 (n)
  • 78.5 (a)
-- 36
  • 77 (a)
(Canis familiaris)
Mammalia LOC608585 35
  • 87.1 (n)
  • 84.52 (a)
-- 36
  • 85 (a)
(Mus musculus)
Mammalia Olfr13 35
  • 80.65 (n)
  • 81.94 (a)
Olfr13 16
Olfr13 36
  • 82 (a)
(Rattus norvegicus)
Mammalia Olr818 35
  • 80.54 (n)
  • 80.65 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 44 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 65 (a)
(Gallus gallus)
Aves -- 36
  • 38 (a)
Species with no ortholog for OR2A7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2A7 Gene

Gene Tree for OR2A7 (if available)
Gene Tree for OR2A7 (if available)

Paralogs for OR2A7 Gene

(457) SIMAP similar genes for OR2A7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2A7: view

Variants for OR2A7 Gene

Sequence variations from dbSNP and Humsavar for OR2A7 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs113628790 -- 144,258,359(+) AACTT(A/C)TTTTT downstream-variant-500B
rs201449000 -- 144,258,207(+) CTCAC(A/G)TAAGT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR2A7 Gene

Variant ID Type Subtype PubMed ID
nsv428188 CNV Gain+Loss 18775914
dgv2148e1 CNV Complex 17122850
nsv8227 CNV Gain+Loss 18304495
esv1682998 OTHER Inversion 17803354
dgv7520n71 CNV Gain 21882294
dgv2149e1 CNV Complex 17122850
dgv2150e1 CNV Complex 17122850
essv3984 CNV CNV 17122850
nsv7411 OTHER Inversion 18451855
dgv7522n71 CNV Gain 21882294
dgv7523n71 CNV Gain 21882294
dgv7524n71 CNV Gain+Loss 21882294
esv1003295 OTHER Inversion 20482838
dgv7525n71 CNV Loss 21882294
nsv821609 CNV Duplication 20802225
nsv824360 CNV Gain 20364138
dgv24n31 CNV Duplication 19718026
nsv819701 CNV Insertion 19587683
esv24292 CNV Gain+Loss 19812545
nsv831175 CNV Loss 17160897
nsv433394 CNV Gain 18776910
nsv508489 CNV Loss 20534489
nsv469769 CNV Complex 16826518
nsv471646 CNV Gain+Loss 15918152
dgv7526n71 CNV Gain 21882294
nsv510970 OTHER Inversion 20534489
esv8347 OTHER Inversion 19470904
nsv515041 CNV Complex 21397061

Relevant External Links for OR2A7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2A7 Gene

Disorders for OR2A7 Gene

No disorders were found for OR2A7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR2A7 Gene

Publications for OR2A7 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR2A7 Gene

Sources for OR2A7 Gene

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