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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OR2A25 Gene

protein-coding   GIFtS: 45
GCID: GC07P143771

Olfactory Receptor, Family 2, Subfamily A, Member 25


(Previous symbols: OR2A25P, OR2A27)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Olfactory Receptor, Family 2, Subfamily A, Member 251 2     Olfactory Receptor 2A252
OR2A25P1 2 3     Olfactory Receptor, Family 2, Subfamily A, Member 24 Pseudogene2
OR2A271 2 3     Olfactory Receptor, Family 2, Subfamily A, Member 25 Pseudogene2
Olfactory Receptor 2A272 3     Olfactory Receptor, Family 2, Subfamily A, Member 272
OR2A24P2     

External Ids:    HGNC: 195621   Entrez Gene: 3921382   Ensembl: ENSG000002219337   UniProtKB: A4D2G33   

Export aliases for OR2A25 gene to outside databases

Previous GC identifers: GC07P143163 GC07P143208 GC07P143402


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OR2A25 Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for OR2A25 Gene: 
OR2A25 (olfactory receptor, family 2, subfamily A, member 25) is a protein-coding gene. Diseases associated with OR2A25 include myocardial infarction, and neuronitis, and among its related super-pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2A4.

UniProtKB/Swiss-Prot: O2A25_HUMAN, A4D2G3
Function: Odorant receptor (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OR2A25 gene promoter:
         AREB6   CREB   PPAR-gamma1   Nkx6-1   POU2F1   deltaCREB   POU2F1a   POU2F1b   PPAR-gamma2   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOR2A25 promoter sequence
   Search SABiosciences Chromatin IP Primers for OR2A25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR2A25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q35   Ensembl cytogenetic band:  7q35   HGNC cytogenetic band: 7q35

OR2A25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OR2A25 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P143771:  view genomic region     (about GC identifiers)

Start:
143,771,313 bp from pter      End:
143,772,242 bp from pter
Size:
930 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 143,109,535-143,110,467     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: O2A25_HUMAN, A4D2G3 (See protein sequence)
Recommended Name: Olfactory receptor 2A25  
Size: 310 amino acids; 34606 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: B2RNC9

Explore the universe of human proteins at neXtProt for OR2A25: NX_A4D2G3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A4D2G3

  • HORDE protein sequence for OR2A25
    OR2A25 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins: NP_001004488.1  
    ENSEMBL proteins: 
     ENSP00000386167  
    Reactome Protein details: A4D2G3
    Human Recombinant Protein Products for OR2A25: 
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    Novus Biologicals OR2A25 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OR2A25 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    OR2A25 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    OR2: GPCR / Class A : Olfactory receptors

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000725 Olfact_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry A4D2G3

    ProtoNet protein and cluster: A4D2G3

    UniProtKB/Swiss-Prot: O2A25_HUMAN, A4D2G3
    Similarity: Belongs to the G-protein coupled receptor 1 family


    OR2A25 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: O2A25_HUMAN, A4D2G3
    Function: Odorant receptor (Potential)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0004984olfactory receptor activity IEA--
         
    OR2A25 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OR2A25 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OR2A25 
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    miRNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR2A25


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for OR2A25 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Olfactory transduction
    Olfactory Signaling Pathway0.81
    Olfactory transduction0.81
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for OR2A25
        GPCR downstream signaling
    Olfactory Signaling Pathway
    Signal Transduction
    Signaling by GPCR


    1         Kegg Pathway  (Kegg details for OR2A25):
        Olfactory transduction


    OR2A25 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR2A25

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/273 Interacting proteins for OR2A25 (ENSP000003861674) via UniProtKB, MINT, STRING, and/or I2D (see all 273)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OR52E6ENSP000003288784STRING: ENSP00000369279 STRING: ENSP00000328878
    GNALENSP000003340514STRING: ENSP00000334051
    GNGT1ENSP000002485724STRING: ENSP00000248572
    OR10A3ENSP000003539884STRING: ENSP00000353988
    OR10A4ENSP000003691574STRING: ENSP00000369157
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----

    OR2A25 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OR2A25 (O2A25)

    Search CenterWatch for drugs/clinical trials and news about OR2A25 / O2A25

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OR2A25 gene: 
    NM_001004488.1  

    Unigene Cluster for OR2A25:

    Olfactory receptor, family 2, subfamily A, member 25
    Hs.553787
    Unigene Representative Sequence: BC136814
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000408898(uc011ktx.2)
    miRNA
    Products:
         
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate OR2A25
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OR2A25
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR2A25
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR2A25
    Sirion Biotech Customized lentivirus for stable overexpression of OR2A25 
                         Customized lentivirus expression plasmids for stable overexpression of OR2A25 
    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR2A25

    Additional mRNA sequence: 

    BC136814.1 BC136829.1 

    1 AceView cDNA sequence:

    NM_001004488 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OR2A25 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGCCTGAA
    OR2A25 Expression
    About this image


    SOURCE GeneReport for Unigene cluster: Hs.553787
        SABiosciences Custom PCR Arrays for OR2A25
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR2A25
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR2A25

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for OR2A25 gene from 1/5 species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfr4471 , 5 olfactory receptor 4471, 5 81.72(n)1
    81.94(a)1
      6 (20.97 cM)5
    2589901  NM_146988.11  NP_667199.11 
     429115255 


    ENSEMBL Gene Tree for OR2A25 (if available)
    TreeFam Gene Tree for OR2A25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OR2A25 gene
    OR2A42  OR2A422  OR2A122  OR2A12  OR2A52  OR2F22  OR2A22  OR2A72  
    OR2D22  OR2F12  OR2D32  OR2A142  
    18/460 SIMAP similar genes for OR2A25 using alignment to 1 protein entry:     O2A25_HUMAN(see all similar genes):
    FKSG35    OR2A1    OR2A4    OR2A7    OR2A42    OR2A5
    OR2A12    OR2A14    OR2A2    OR10A7    OR2C1    OR4K2
    OR4Q3    OR13F1    OR10R3P    OR2B8P    OR2G6    OR2Y1

    OR2A25 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/105 SNPs in OR2A25 are shown (see all 105)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1864263141,2
    --143769429(+) TTTAAA/TACATT 1 -- us2k10--------
    rs1896150221,2
    --143769446(+) GCCACA/GAAAAA 1 -- us2k10--------
    rs125330961,2
    C,H--143769630(+) AATTCA/GGCCAG 1 -- us2k14Minor allele frequency- G:0.00NS EA 420
    rs798977101,2
    C,F--143769700(+) ACACAG/AAGTAA 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs1474812841,2
    --143769721(+) GTATAG/TGTACT 1 -- us2k10--------
    rs1400291311,2
    --143769734(+) TGTGTA/GTATGT 1 -- us2k10--------
    rs1808947301,2
    --143769877(+) GATATC/TTTCAC 1 -- us2k10--------
    rs1858874941,2
    --143769954(+) GAATGA/GATAAA 1 -- us2k10--------
    rs1418288941,2
    C--143770260(+) TAGTGA/TTCAAT 1 -- us2k10--------
    rs1506247831,2
    --143770387(+) AGCCCA/CAGTAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OR2A25 ( 143771313 - 143772242 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for OR2A25 (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv471453CNV Duplication19718026
    nsv831174CNV Loss17160897
    esv1006326CNV Gain20482838
    nsv522225CNV Gain19592680
    esv2752147CNV Gain17911159
    dgv842n27CNV Gain19166990
    dgv7520n71CNV Gain21882294
    nsv831173CNV Gain17160897
    nsv889336CNV Gain21882294
    dgv7521n71CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing OR2A25
    DNA2.0 Custom Variant and Variant Library Synthesis for OR2A25

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for OR2A25:    About MalaCards
    myocardial infarction    neuronitis


    OR2A25 for disorders           About GeneDecksing

    Genetic Association Database (GAD): OR2A25
    Human Genome Epidemiology (HuGE) Navigator: OR2A25 (2 documents)

    Export disorders for OR2A25 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OR2A25 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with OR2A25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)1, 4 Luke M.M....Psaty B.M. (2009)
    2. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PubMed id 17975119)1, 4 Shiffman D....Psaty B.M. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
    5. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 392138 HGNC: 19562 AceView: OR2A25 Ensembl:ENSG00000221933 euGenes: HUgn392138
    ECgene: OR2A25 Kegg: 392138 H-InvDB: OR2A25

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OR2A25 Pharmacogenomics, SNPs, Pathways
    HORDE entry for OR2A25 The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OR2A25 gene:
    Search GeneIP for patents involving OR2A25

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Proteins for OR2A25
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR2A25
     inGenious Targeting Laboratory - Custom generated mouse model solutions for OR2A25
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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