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Aliases for OR1Q1 Gene

Aliases for OR1Q1 Gene

  • Olfactory Receptor Family 1 Subfamily Q Member 1 2 3 5
  • Olfactory Receptor TPCR106 3 4
  • Olfactory Receptor OR9-25 3 4
  • Olfactory Receptor 1Q2 3 4
  • Olfactory Receptor 1Q3 3 4
  • Olfactory Receptor 9-A 3 4
  • OST226 3 4
  • OR1Q2 3 4
  • OR1Q3 3 4
  • OR9-A 3 4
  • Olfactory Receptor, Family 1, Subfamily Q, Member 1 2
  • Olfactory Receptor, Family 1, Subfamily Q, Member 2 3
  • Olfactory Receptor, Family 1, Subfamily Q, Member 3 3
  • Olfactory Receptor 1Q1 3
  • OST226OR9-A 3
  • HSTPCR106 3
  • TPCR106 3
  • OR9-25 3

External Ids for OR1Q1 Gene

Previous HGNC Symbols for OR1Q1 Gene

  • OR1Q2
  • OR1Q3

Previous GeneCards Identifiers for OR1Q1 Gene

  • GC09U990112
  • GC09M117023
  • GC09P118830
  • GC09P120753
  • GC09P120749
  • GC09P122456
  • GC09P124416
  • GC09P125376
  • GC09P122614

Summaries for OR1Q1 Gene

Entrez Gene Summary for OR1Q1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1Q1 Gene

OR1Q1 (Olfactory Receptor Family 1 Subfamily Q Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1L4.

UniProtKB/Swiss-Prot for OR1Q1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1Q1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1Q1 Gene

Genomics for OR1Q1 Gene

Regulatory Elements for OR1Q1 Gene

Enhancers for OR1Q1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F122463 1.2 Ensembl ENCODE 15.9 -103.6 -103616 2.0 PKNOX1 ARID4B BRCA1 ZNF2 RAD21 RFX5 CHAMP1 ZNF143 RCOR1 DEK OR1Q1 OR1K1 OR1N1 OR1J4 PTGS1 OR5C1 RBM18 MRRF TTLL11 ENSG00000231465
GH09F122355 0.3 FANTOM5 49.1 -212.6 -212626 0.0 OR1Q1 OR1L8 OR1J2 OR1B1 OR1L1 OR1N2 OR1J4 MRRF OR1L4 OR1K1
GH09F122393 0.9 Ensembl ENCODE 9.6 -174.0 -174007 2.7 ARID1B STAT1 PKNOX1 JUND ATF3 IKZF1 CEBPB FOS PTGS1 OR1K1 OR1Q1 OR1N2 ENSG00000233616 ENSG00000269970
GH09F122468 0.2 ENCODE 26.9 -99.5 -99534 1.5 OR1Q1 OR1J4 OR1K1 OR5C1 ENSG00000231465 OR1J2
GH09F122766 0.3 FANTOM5 10.5 +198.6 198625 0.4 OR1J4 OR1N2 OR1L8 OR1K1 OR5C1 OR1Q1 OR1J2 OR1L1 OR1B1 OR1L4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR1Q1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR1Q1 Gene

Chromosome:
9
Start:
122,568,380 bp from pter
End:
122,615,830 bp from pter
Size:
47,451 bases
Orientation:
Plus strand

Genomic View for OR1Q1 Gene

Genes around OR1Q1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1Q1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1Q1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1Q1 Gene

Proteins for OR1Q1 Gene

  • Protein details for OR1Q1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15612-OR1Q1_HUMAN
    Recommended name:
    Olfactory receptor 1Q1
    Protein Accession:
    Q15612
    Secondary Accessions:
    • Q6IFN4
    • Q8NGR7
    • Q96R82

    Protein attributes for OR1Q1 Gene

    Size:
    314 amino acids
    Molecular mass:
    35598 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1Q1 Gene

Post-translational modifications for OR1Q1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR1Q1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1Q1 Gene

Domains & Families for OR1Q1 Gene

Gene Families for OR1Q1 Gene

Protein Domains for OR1Q1 Gene

Suggested Antigen Peptide Sequences for OR1Q1 Gene

Graphical View of Domain Structure for InterPro Entry

Q15612

UniProtKB/Swiss-Prot:

OR1Q1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1Q1: view

Function for OR1Q1 Gene

Molecular function for OR1Q1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9119360
genes like me logo Genes that share ontologies with OR1Q1: view
genes like me logo Genes that share phenotypes with OR1Q1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for OR1Q1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1Q1 Gene

Localization for OR1Q1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1Q1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR1Q1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 9119360
genes like me logo Genes that share ontologies with OR1Q1: view

Pathways & Interactions for OR1Q1 Gene

genes like me logo Genes that share pathways with OR1Q1: view

Pathways by source for OR1Q1 Gene

1 KEGG pathway for OR1Q1 Gene

Gene Ontology (GO) - Biological Process for OR1Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 9119360
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR1Q1: view

No data available for SIGNOR curated interactions for OR1Q1 Gene

Transcripts for OR1Q1 Gene

mRNA/cDNA for OR1Q1 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR1Q1 Gene

No ASD Table

Relevant External Links for OR1Q1 Gene

GeneLoc Exon Structure for
OR1Q1
ECgene alternative splicing isoforms for
OR1Q1

Expression for OR1Q1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR1Q1 Gene

mRNA differential expression in normal tissues according to GTEx for OR1Q1 Gene

This gene is overexpressed in Bladder (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of OR1Q1 Gene:

OR1Q1

SOURCE GeneReport for Unigene cluster for OR1Q1 Gene:

Hs.684864
genes like me logo Genes that share expression patterns with OR1Q1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR1Q1 Gene

Orthologs for OR1Q1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR1Q1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC736157 34
  • 99.68 (n)
OR1Q1 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR1Q1 34 35
  • 84.29 (n)
mouse
(Mus musculus)
Mammalia Or1q1 55 Olfr357 34 16 35
  • 82.25 (n)
rat
(Rattus norvegicus)
Mammalia Olr420 34
  • 80.74 (n)
oppossum
(Monodelphis domestica)
Mammalia OPOR54 35
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 35
  • 40 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 49 (a)
ManyToMany
-- 35
  • 47 (a)
ManyToMany
-- 35
  • 45 (a)
ManyToMany
-- 35
  • 44 (a)
ManyToMany
Species where no ortholog for OR1Q1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1Q1 Gene

ENSEMBL:
Gene Tree for OR1Q1 (if available)
TreeFam:
Gene Tree for OR1Q1 (if available)

Paralogs for OR1Q1 Gene

(458) SIMAP similar genes for OR1Q1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR1Q1: view

Variants for OR1Q1 Gene

Sequence variations from dbSNP and Humsavar for OR1Q1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10818730 -- 122,613,049(+) TCATT(C/T)TGCGA intron-variant, upstream-variant-2KB
rs10985732 -- 122,613,605(+) CTCTT(A/C)TAATC intron-variant, upstream-variant-2KB
rs10985733 -- 122,614,944(+) TTGAC(A/C/G)GACAT intron-variant, reference, synonymous-codon
rs111602091 -- 122,614,847(+) CGCAA(C/T)CAATA intron-variant, reference, missense
rs111835949 -- 122,615,037(+) GCCCA(A/G)ACTTA intron-variant, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR1Q1 Gene

Variant ID Type Subtype PubMed ID
nsv1039785 CNV gain 25217958
nsv972804 CNV duplication 23825009
nsv1054800 CNV loss 25217958

Variation tolerance for OR1Q1 Gene

Residual Variation Intolerance Score: 85.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.88; 79.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR1Q1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR1Q1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1Q1 Gene

Disorders for OR1Q1 Gene

Relevant External Links for OR1Q1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR1Q1

No disorders were found for OR1Q1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1Q1 Gene

Publications for OR1Q1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64
  3. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 3 4 64
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64
  5. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64

Products for OR1Q1 Gene

Sources for OR1Q1 Gene

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