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Aliases for OR1P1 Gene

Aliases for OR1P1 Gene

  • Olfactory Receptor Family 1 Subfamily P Member 1 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 1, Subfamily P, Member 1 Pseudogene 2 3
  • OR17-208 3 4
  • OR1P1P 3 4
  • Olfactory Receptor, Family 1, Subfamily P, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor 17-208 4
  • Olfactory Receptor OR17-9 4

External Ids for OR1P1 Gene

Previous HGNC Symbols for OR1P1 Gene

  • OR1P1P

Previous GeneCards Identifiers for OR1P1 Gene

  • GC17M003004
  • GC17M003057
  • GC17M002949

Summaries for OR1P1 Gene

Entrez Gene Summary for OR1P1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1P1 Gene

OR1P1 (Olfactory Receptor Family 1 Subfamily P Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR1P1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1P1 Gene

Genomics for OR1P1 Gene

Regulatory Elements for OR1P1 Gene

Enhancers for OR1P1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F003153 0.4 Ensembl 0.8 +1.6 1582 0.2 ZBTB48 OR1A2 OR1E2 OR1P1 GC17M003136
GH17F003167 0.7 Ensembl ENCODE 0.4 -12.9 -12917 0.8 IKZF1 PRDM1 SPI1 OR1A2 OR1E2 ENSG00000261848 OR1P1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR1P1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR1P1 Gene

Chromosome:
17
Start:
3,153,889 bp from pter
End:
3,154,882 bp from pter
Size:
994 bases
Orientation:
Minus strand

Genomic View for OR1P1 Gene

Genes around OR1P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1P1 Gene

Proteins for OR1P1 Gene

  • Protein details for OR1P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH06-OR1P1_HUMAN
    Recommended name:
    Olfactory receptor 1P1
    Protein Accession:
    Q8NH06

    Protein attributes for OR1P1 Gene

    Size:
    330 amino acids
    Molecular mass:
    36638 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1P1 Gene

Post-translational modifications for OR1P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OR1P1 Gene

Domains & Families for OR1P1 Gene

Gene Families for OR1P1 Gene

Protein Domains for OR1P1 Gene

Suggested Antigen Peptide Sequences for OR1P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH06

UniProtKB/Swiss-Prot:

OR1P1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1P1: view

Function for OR1P1 Gene

Molecular function for OR1P1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1P1: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1P1 Gene

Localization for OR1P1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1P1 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR1P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1P1: view

No data available for Subcellular locations from COMPARTMENTS for OR1P1 Gene

Pathways & Interactions for OR1P1 Gene

genes like me logo Genes that share pathways with OR1P1: view

Pathways by source for OR1P1 Gene

Interacting Proteins for OR1P1 Gene

Gene Ontology (GO) - Biological Process for OR1P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1P1: view

No data available for SIGNOR curated interactions for OR1P1 Gene

Transcripts for OR1P1 Gene

mRNA/cDNA for OR1P1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1P1 Gene

No ASD Table

Relevant External Links for OR1P1 Gene

GeneLoc Exon Structure for
OR1P1
ECgene alternative splicing isoforms for
OR1P1

Expression for OR1P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR1P1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR1P1 Gene:

OR1P1
genes like me logo Genes that share expression patterns with OR1P1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR1P1 Gene

Orthologs for OR1P1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR1P1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Or1p1 55 Olfr59
  • chr11:74,288,648-74,289,616
Or1p1b 55 Olfr404
  • chr11:74,239,566-74,240,447
Or1p1c 55 Olfr406
  • chr11:74,269,391-74,270,359
Or1p4-ps 55 Olfr409-ps1
  • chr11:74,317,027-74,317,994
Species where no ortholog for OR1P1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1P1 Gene

ENSEMBL:
Gene Tree for OR1P1 (if available)
TreeFam:
Gene Tree for OR1P1 (if available)

Paralogs for OR1P1 Gene

(452) SIMAP similar genes for OR1P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1P1: view

No data available for Paralogs for OR1P1 Gene

Variants for OR1P1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR1P1 Gene

OR1P1_HUMAN-Q8NH06
A stop codon in the gene coding for this protein at position Ala-185 is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans.

Relevant External Links for OR1P1 Gene

Human Gene Mutation Database (HGMD)
OR1P1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR1P1

No data available for Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR1P1 Gene

Disorders for OR1P1 Gene

No disorders were found for OR1P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR1P1 Gene

Publications for OR1P1 Gene

  1. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 2 3 4 64
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  4. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 3 4 64
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64

Products for OR1P1 Gene

Sources for OR1P1 Gene

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