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Aliases for OR1M1 Gene

Aliases for OR1M1 Gene

  • Olfactory Receptor Family 1 Subfamily M Member 1 2 3 5
  • Olfactory Receptor, Family 1, Subfamily M, Member 1 2 3
  • Olfactory Receptor OR19-5 3 4
  • Olfactory Receptor 19-6 3 4
  • OR19-6 3 4
  • OR19-5 3

External Ids for OR1M1 Gene

Previous GeneCards Identifiers for OR1M1 Gene

  • GC19U990197
  • GC19P009065
  • GC19P009203

Summaries for OR1M1 Gene

Entrez Gene Summary for OR1M1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1M1 Gene

OR1M1 (Olfactory Receptor Family 1 Subfamily M Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1M1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1M1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1M1 Gene

Genomics for OR1M1 Gene

Regulatory Elements for OR1M1 Gene

Genomic Location for OR1M1 Gene

Chromosome:
19
Start:
9,093,179 bp from pter
End:
9,094,213 bp from pter
Size:
1,035 bases
Orientation:
Plus strand

Genomic View for OR1M1 Gene

Genes around OR1M1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1M1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1M1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1M1 Gene

Proteins for OR1M1 Gene

  • Protein details for OR1M1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGA1-OR1M1_HUMAN
    Recommended name:
    Olfactory receptor 1M1
    Protein Accession:
    Q8NGA1
    Secondary Accessions:
    • B9EHA6
    • Q6IFJ3
    • Q96R91

    Protein attributes for OR1M1 Gene

    Size:
    313 amino acids
    Molecular mass:
    34840 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1M1 Gene

Proteomics data for OR1M1 Gene at MOPED

Post-translational modifications for OR1M1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR1M1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1M1 Gene

Domains & Families for OR1M1 Gene

Gene Families for OR1M1 Gene

Protein Domains for OR1M1 Gene

Suggested Antigen Peptide Sequences for OR1M1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGA1

UniProtKB/Swiss-Prot:

OR1M1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1M1: view

Function for OR1M1 Gene

Molecular function for OR1M1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 1,subfamily M,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1M1: view
genes like me logo Genes that share phenotypes with OR1M1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1M1 Gene

Localization for OR1M1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1M1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1M1 Gene COMPARTMENTS Subcellular localization image for OR1M1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR1M1: view

Pathways & Interactions for OR1M1 Gene

genes like me logo Genes that share pathways with OR1M1: view

Pathways by source for OR1M1 Gene

Interacting Proteins for OR1M1 Gene

Gene Ontology (GO) - Biological Process for OR1M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1M1: view

No data available for SIGNOR curated interactions for OR1M1 Gene

Drugs & Compounds for OR1M1 Gene

No Compound Related Data Available

Transcripts for OR1M1 Gene

mRNA/cDNA for OR1M1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1M1 Gene

No ASD Table

Relevant External Links for OR1M1 Gene

GeneLoc Exon Structure for
OR1M1
ECgene alternative splicing isoforms for
OR1M1

Expression for OR1M1 Gene

mRNA expression in normal human tissues for OR1M1 Gene

Protein differential expression in normal tissues from HIPED for OR1M1 Gene

This gene is overexpressed in Oral epithelium (8.6), Bone marrow stromal cell (8.5), Retina (8.3), and Placenta (8.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR1M1 Gene



SOURCE GeneReport for Unigene cluster for OR1M1 Gene Hs.553577

genes like me logo Genes that share expression patterns with OR1M1: view

Protein tissue co-expression partners for OR1M1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR1M1 Gene

Orthologs for OR1M1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1M1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC513175 35
  • 85.09 (n)
  • 85.3 (a)
OR1M1 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR1M1 35
  • 85.84 (n)
  • 88.18 (a)
OR08C10 36
  • 87 (a)
OneToMany
OR08F07 36
  • 85 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr24 35
  • 83.81 (n)
  • 85.3 (a)
Olfr24 16
Olfr24 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1121 35
  • 82.22 (n)
  • 85.94 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
OneToMany
-- 36
  • 77 (a)
OneToMany
Species with no ortholog for OR1M1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1M1 Gene

ENSEMBL:
Gene Tree for OR1M1 (if available)
TreeFam:
Gene Tree for OR1M1 (if available)

Paralogs for OR1M1 Gene

(455) SIMAP similar genes for OR1M1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR1M1 Gene

genes like me logo Genes that share paralogs with OR1M1: view

Variants for OR1M1 Gene

Sequence variations from dbSNP and Humsavar for OR1M1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2053073 -- 9,092,440(-) ctttt(C/T)ttgtg upstream-variant-2KB
rs2053074 -- 9,091,409(-) TTTAT(C/T)CTTAG upstream-variant-2KB
rs4804095 -- 9,093,079(+) ATATA(C/T)ACACA upstream-variant-2KB
rs4804096 -- 9,093,109(+) ACACA(C/T)ATATA upstream-variant-2KB
rs4804097 -- 9,093,631(+) CACCC(A/G)TTGCA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR1M1 Gene

Variant ID Type Subtype PubMed ID
nsv509720 CNV Insertion 20534489

Variation tolerance for OR1M1 Gene

Residual Variation Intolerance Score: 80.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.89; 48.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR1M1 Gene

HapMap Linkage Disequilibrium report
OR1M1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1M1 Gene

Disorders for OR1M1 Gene

Relevant External Links for OR1M1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR1M1

No disorders were found for OR1M1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1M1 Gene

Publications for OR1M1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR1M1 Gene

Sources for OR1M1 Gene

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