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Aliases for OR1L3 Gene

Aliases for OR1L3 Gene

  • Olfactory Receptor, Family 1, Subfamily L, Member 3 2 3
  • Olfactory Receptor OR9-28 3 4
  • Olfactory Receptor 9-D 3 4
  • OR9-D 3 4
  • Olfactory Receptor 1L3 3
  • OR9-28 3

External Ids for OR1L3 Gene

Previous GeneCards Identifiers for OR1L3 Gene

  • GC09U990115
  • GC09P122516
  • GC09P124477
  • GC09P125438

Summaries for OR1L3 Gene

Entrez Gene Summary for OR1L3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1L3 Gene

OR1L3 (Olfactory Receptor, Family 1, Subfamily L, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1D5.

UniProtKB/Swiss-Prot for OR1L3 Gene

  • Odorant receptor.

Gene Wiki entry for OR1L3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1L3 Gene

Genomics for OR1L3 Gene

Regulatory Elements for OR1L3 Gene

Genomic Location for OR1L3 Gene

Start:
122,675,130 bp from pter
End:
122,676,104 bp from pter
Size:
975 bases
Orientation:
Plus strand

Genomic View for OR1L3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1L3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1L3 Gene

Proteins for OR1L3 Gene

  • Protein details for OR1L3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH93-OR1L3_HUMAN
    Recommended name:
    Olfactory receptor 1L3
    Protein Accession:
    Q8NH93
    Secondary Accessions:
    • B2RNF4
    • Q6IFN1

    Protein attributes for OR1L3 Gene

    Size:
    324 amino acids
    Molecular mass:
    36633 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1L3 Gene

Proteomics data for OR1L3 Gene at MOPED

Post-translational modifications for OR1L3 Gene

Other Protein References for OR1L3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1L3 Gene

Domains for OR1L3 Gene

Gene Families for OR1L3 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1L3 Gene

Suggested Antigen Peptide Sequences for OR1L3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH93

UniProtKB/Swiss-Prot:

OR1L3_HUMAN :
  • Q8NH93
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1L3: view

Function for OR1L3 Gene

Molecular function for OR1L3 Gene

GENATLAS Biochemistry: olfactory receptor,family 1,subfamily L,member 3,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1L3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1L3 Gene

Localization for OR1L3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1L3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1L3 Gene COMPARTMENTS Subcellular localization image for OR1L3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1L3: view

Pathways for OR1L3 Gene

genes like me logo Genes that share pathways with OR1L3: view

Pathways by source for OR1L3 Gene

Interacting Proteins for OR1L3 Gene

Gene Ontology (GO) - Biological Process for OR1L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR1L3: view

Transcripts for OR1L3 Gene

mRNA/cDNA for OR1L3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1L3 Gene

No ASD Table

Relevant External Links for OR1L3 Gene

GeneLoc Exon Structure for
OR1L3
ECgene alternative splicing isoforms for
OR1L3

Expression for OR1L3 Gene

mRNA expression in normal human tissues for OR1L3 Gene

SOURCE GeneReport for Unigene cluster for OR1L3 Gene Hs.626839

genes like me logo Genes that share expressions with OR1L3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR1L3 Gene

Orthologs for OR1L3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1L3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR1L3 35
  • 86.79 (n)
  • 83.59 (a)
OR1L3 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OPOR48 36
  • 48 (a)
ManyToMany
Species with no ortholog for OR1L3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1L3 Gene

ENSEMBL:
Gene Tree for OR1L3 (if available)
TreeFam:
Gene Tree for OR1L3 (if available)

Paralogs for OR1L3 Gene

Paralogs for OR1L3 Gene

Selected SIMAP similar genes for OR1L3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1L3: view

Variants for OR1L3 Gene

Sequence variations from dbSNP and Humsavar for OR1L3 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs7030596 -- 122,674,051(+) TATCT(C/T)GTTAC upstream-variant-2KB
rs7044366 -- 122,673,649(+) GCCTG(A/G)TGAGA upstream-variant-2KB
rs7044945 -- 122,673,868(+) TTCTC(A/G)CAAAA upstream-variant-2KB
rs7045047 -- 122,673,905(+) TCCCC(A/G)TGTTT upstream-variant-2KB
rs7045172 -- 122,673,998(+) CATCT(G/T)GACTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR1L3 Gene

Variant ID Type Subtype PubMed ID
esv6464 OTHER Inversion 19470904

Relevant External Links for OR1L3 Gene

HapMap Linkage Disequilibrium report
OR1L3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1L3 Gene

Disorders for OR1L3 Gene

No disorders were found for OR1L3 Gene.

No data available for UniProtKB/Swiss-Prot for OR1L3 Gene

Publications for OR1L3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR1L3 Gene

Sources for OR1L3 Gene

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