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Aliases for OR1L1 Gene

Aliases for OR1L1 Gene

  • Olfactory Receptor, Family 1, Subfamily L, Member 1 2 3
  • Olfactory Receptor OR9-27 3 4
  • Olfactory Receptor 1L2 3 4
  • Olfactory Receptor 9-C 3 4
  • OR1L2 3 4
  • OR9-C 3 4
  • Olfactory Receptor, Family 1, Subfamily L, Member 2 3
  • Olfactory Receptor 1L1 3
  • OR9-27 3
  • HG23 3

External Ids for OR1L1 Gene

Previous Symbols for OR1L1 Gene

  • OR1L2

Summaries for OR1L1 Gene

Entrez Gene Summary for OR1L1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1L1 Gene

OR1L1 (Olfactory Receptor, Family 1, Subfamily L, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1D5.

UniProtKB/Swiss-Prot for OR1L1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1L1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1L1 Gene

Genomics for OR1L1 Gene

Genomic Location for OR1L1 Gene

Start:
122,661,566 bp from pter
End:
122,662,648 bp from pter
Size:
1,083 bases
Orientation:
Plus strand

Genomic View for OR1L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1L1 Gene

Regulatory Elements for OR1L1 Gene

Proteins for OR1L1 Gene

  • Protein details for OR1L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH94-OR1L1_HUMAN
    Recommended name:
    Olfactory receptor 1L1
    Protein Accession:
    Q8NH94
    Secondary Accessions:
    • Q5T7Z3
    • Q6IFN2

    Protein attributes for OR1L1 Gene

    Size:
    360 amino acids
    Molecular mass:
    41046 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05743.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=EAW87540.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for OR1L1 Gene

Proteomics data for OR1L1 Gene at MOPED

Post-translational modifications for OR1L1 Gene

  • Glycosylation at Asn55 and Asn315

Other Protein References for OR1L1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR1L1 Gene

Domains for OR1L1 Gene

Gene Families for OR1L1 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1L1 Gene

UniProtKB/Swiss-Prot:

OR1L1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NH94
genes like me logo Genes that share domains with OR1L1: view

Function for OR1L1 Gene

Molecular function for OR1L1 Gene

GENATLAS Biochemistry: olfactory receptor,family 1,subfamily L,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1L1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1L1 Gene

Localization for OR1L1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1L1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1L1 Gene COMPARTMENTS Subcellular localization image for OR1L1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1L1: view

Pathways for OR1L1 Gene

genes like me logo Genes that share pathways with OR1L1: view

Pathways by source for OR1L1 Gene

Interacting Proteins for OR1L1 Gene

Gene Ontology (GO) - Biological Process for OR1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR1L1: view

Transcripts for OR1L1 Gene

mRNA/cDNA for OR1L1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1L1 Gene

No ASD Table

Relevant External Links for OR1L1 Gene

GeneLoc Exon Structure for
OR1L1
ECgene alternative splicing isoforms for
OR1L1

Expression for OR1L1 Gene

mRNA expression in normal human tissues for OR1L1 Gene

SOURCE GeneReport for Unigene cluster for OR1L1 Gene Hs.567736

genes like me logo Genes that share expressions with OR1L1: view

Orthologs for OR1L1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1L1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC473046 36
  • 99.03 (n)
  • 98.71 (a)
OR1L1 37
  • 85 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC785392 36
  • 86.77 (n)
  • 90.97 (a)
OR1L1 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr366 37
  • 62 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 51 (a)
ManyToMany
Species with no ortholog for OR1L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1L1 Gene

ENSEMBL:
Gene Tree for OR1L1 (if available)
TreeFam:
Gene Tree for OR1L1 (if available)

Paralogs for OR1L1 Gene

Paralogs for OR1L1 Gene

Selected SIMAP similar genes for OR1L1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1L1: view

Variants for OR1L1 Gene

Sequence variations from dbSNP and Humsavar for OR1L1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs70156 -- 122,662,228(+) GCCTC(A/C)AATGT reference, synonymous-codon
rs70157 - 122,661,998(+) CTTAC(A/G)GTGAG reference, missense
rs237617 -- 122,660,586(+) TCTTC(A/G)GCTTC upstream-variant-2KB
rs237618 -- 122,660,788(+) Tggcc(A/G)ggtgc upstream-variant-2KB
rs237619 -- 122,661,164(+) GGTTT(C/T)ACTAA upstream-variant-2KB

Relevant External Links for OR1L1 Gene

HapMap Linkage Disequilibrium report
OR1L1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR1L1 Gene

Disorders for OR1L1 Gene

(1) University of Copenhagen DISEASES for OR1L1 Gene

genes like me logo Genes that share disorders with OR1L1: view

No data available for UniProtKB/Swiss-Prot for OR1L1 Gene

Publications for OR1L1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4

Products for OR1L1 Gene

Sources for OR1L1 Gene

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