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Aliases for OR1J4 Gene

Aliases for OR1J4 Gene

  • Olfactory Receptor Family 1 Subfamily J Member 4 2 3 5
  • Olfactory Receptor, Family 1, Subfamily J, Member 4 2 3
  • Olfactory Receptor OR9-21 3 4
  • HTPCRX01 3 4
  • HSHTPCRX01 3
  • OR9-21 3

External Ids for OR1J4 Gene

Previous GeneCards Identifiers for OR1J4 Gene

  • GC09P116386
  • GC09U900014
  • GC09P118735
  • GC09P120614
  • GC09P122360
  • GC09P124313
  • GC09P125281

Summaries for OR1J4 Gene

Entrez Gene Summary for OR1J4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1J4 Gene

OR1J4 (Olfactory Receptor Family 1 Subfamily J Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1J4 Gene

  • Odorant receptor.

Gene Wiki entry for OR1J4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1J4 Gene

Genomics for OR1J4 Gene

Regulatory Elements for OR1J4 Gene

Genomic Location for OR1J4 Gene

Chromosome:
9
Start:
122,519,141 bp from pter
End:
122,520,082 bp from pter
Size:
942 bases
Orientation:
Plus strand

Genomic View for OR1J4 Gene

Genes around OR1J4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1J4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1J4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1J4 Gene

Proteins for OR1J4 Gene

  • Protein details for OR1J4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGS1-OR1J4_HUMAN
    Recommended name:
    Olfactory receptor 1J4
    Protein Accession:
    Q8NGS1
    Secondary Accessions:
    • A3KFM0
    • Q6IEZ3
    • Q96R89

    Protein attributes for OR1J4 Gene

    Size:
    313 amino acids
    Molecular mass:
    34959 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1J4 Gene

Proteomics data for OR1J4 Gene at MOPED

Post-translational modifications for OR1J4 Gene

Other Protein References for OR1J4 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1J4 Gene

Domains & Families for OR1J4 Gene

Gene Families for OR1J4 Gene

Protein Domains for OR1J4 Gene

Suggested Antigen Peptide Sequences for OR1J4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGS1

UniProtKB/Swiss-Prot:

OR1J4_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1J4: view

Function for OR1J4 Gene

Molecular function for OR1J4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1J4: view

Phenotypes for OR1J4 Gene

genes like me logo Genes that share phenotypes with OR1J4: view

Animal Model Products

  • Taconic Biosciences Mouse Models for OR1J4

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1J4 Gene

Localization for OR1J4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1J4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1J4 Gene COMPARTMENTS Subcellular localization image for OR1J4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR1J4: view

Pathways & Interactions for OR1J4 Gene

genes like me logo Genes that share pathways with OR1J4: view

Pathways by source for OR1J4 Gene

Interacting Proteins for OR1J4 Gene

Gene Ontology (GO) - Biological Process for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1J4: view

No data available for SIGNOR curated interactions for OR1J4 Gene

Drugs & Compounds for OR1J4 Gene

No Compound Related Data Available

Transcripts for OR1J4 Gene

mRNA/cDNA for OR1J4 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1J4 Gene

No ASD Table

Relevant External Links for OR1J4 Gene

GeneLoc Exon Structure for
OR1J4
ECgene alternative splicing isoforms for
OR1J4

Expression for OR1J4 Gene

mRNA expression in normal human tissues for OR1J4 Gene

mRNA differential expression in normal tissues according to GTEx for OR1J4 Gene

This gene is overexpressed in Testis (x4.1).

SOURCE GeneReport for Unigene cluster for OR1J4 Gene Hs.632679

genes like me logo Genes that share expression patterns with OR1J4: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR1J4 Gene

Orthologs for OR1J4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1J4 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC508604 35
  • 86.26 (n)
  • 83.07 (a)
-- 36
  • 76 (a)
OneToMany
-- 36
  • 77 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 83 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
-- 36
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr350 35
  • 83.76 (n)
  • 80 (a)
Olfr350 16
Olfr350 36
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC473041 35
  • 99.57 (n)
  • 99.36 (a)
OR1J4 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr413 35
  • 83.55 (n)
  • 80.65 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
OneToMany
Species with no ortholog for OR1J4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1J4 Gene

ENSEMBL:
Gene Tree for OR1J4 (if available)
TreeFam:
Gene Tree for OR1J4 (if available)

Paralogs for OR1J4 Gene

(459) SIMAP similar genes for OR1J4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR1J4: view

Variants for OR1J4 Gene

Structural Variations from Database of Genomic Variants (DGV) for OR1J4 Gene

Variant ID Type Subtype PubMed ID
nsv893822 CNV Gain 21882294
nsv893823 CNV Loss 21882294
nsv893824 CNV Loss 21882294

Variation tolerance for OR1J4 Gene

Residual Variation Intolerance Score: 70% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.19; 23.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR1J4 Gene

HapMap Linkage Disequilibrium report
OR1J4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for OR1J4 Gene

Disorders for OR1J4 Gene

Relevant External Links for OR1J4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR1J4

No disorders were found for OR1J4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1J4 Gene

Publications for OR1J4 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3 4 67
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR1J4 Gene

Sources for OR1J4 Gene

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