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Aliases for OR1J4 Gene

Aliases for OR1J4 Gene

  • Olfactory Receptor, Family 1, Subfamily J, Member 4 2 3
  • Olfactory Receptor OR9-21 3 4
  • HTPCRX01 3 4
  • Olfactory Receptor 1J4 3
  • HSHTPCRX01 3
  • OR9-21 3

External Ids for OR1J4 Gene

Previous GeneCards Identifiers for OR1J4 Gene

  • GC09P116386
  • GC09U900014
  • GC09P118735
  • GC09P120614
  • GC09P122360
  • GC09P124313
  • GC09P125281

Summaries for OR1J4 Gene

Entrez Gene Summary for OR1J4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1J4 Gene

OR1J4 (Olfactory Receptor, Family 1, Subfamily J, Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1J4 Gene

  • Odorant receptor.

Gene Wiki entry for OR1J4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1J4 Gene

Genomics for OR1J4 Gene

Regulatory Elements for OR1J4 Gene

Genomic Location for OR1J4 Gene

Start:
122,519,141 bp from pter
End:
122,520,082 bp from pter
Size:
942 bases
Orientation:
Plus strand

Genomic View for OR1J4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1J4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1J4 Gene

Proteins for OR1J4 Gene

  • Protein details for OR1J4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGS1-OR1J4_HUMAN
    Recommended name:
    Olfactory receptor 1J4
    Protein Accession:
    Q8NGS1
    Secondary Accessions:
    • A3KFM0
    • Q6IEZ3
    • Q96R89

    Protein attributes for OR1J4 Gene

    Size:
    313 amino acids
    Molecular mass:
    34959 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1J4 Gene

Proteomics data for OR1J4 Gene at MOPED

Post-translational modifications for OR1J4 Gene

Other Protein References for OR1J4 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1J4 Gene

Domains for OR1J4 Gene

Gene Families for OR1J4 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1J4 Gene

Suggested Antigen Peptide Sequences for OR1J4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGS1

UniProtKB/Swiss-Prot:

OR1J4_HUMAN :
  • Q8NGS1
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1J4: view

Function for OR1J4 Gene

Molecular function for OR1J4 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1J4: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1J4 Gene

Localization for OR1J4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1J4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1J4 Gene COMPARTMENTS Subcellular localization image for OR1J4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1J4: view

Pathways for OR1J4 Gene

genes like me logo Genes that share pathways with OR1J4: view

Pathways by source for OR1J4 Gene

Interacting Proteins for OR1J4 Gene

Gene Ontology (GO) - Biological Process for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1J4: view

Transcripts for OR1J4 Gene

mRNA/cDNA for OR1J4 Gene

(2) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1J4 Gene

No ASD Table

Relevant External Links for OR1J4 Gene

GeneLoc Exon Structure for
OR1J4
ECgene alternative splicing isoforms for
OR1J4

Expression for OR1J4 Gene

mRNA expression in normal human tissues for OR1J4 Gene

mRNA differential expression in normal tissues according to GTEx for OR1J4 Gene

This gene is overexpressed in Testis (4.1).

SOURCE GeneReport for Unigene cluster for OR1J4 Gene Hs.632679

genes like me logo Genes that share expressions with OR1J4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for OR1J4 Gene

Orthologs for OR1J4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1J4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC473041 35
  • 99.57 (n)
  • 99.36 (a)
OR1J4 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 76 (a)
OneToMany
-- 36
  • 77 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 83 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
-- 36
  • 75 (a)
OneToMany
LOC508604 35
  • 86.26 (n)
  • 83.07 (a)
mouse
(Mus musculus)
Mammalia Olfr350 35
  • 83.76 (n)
  • 80 (a)
Olfr350 16
Olfr350 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr413 35
  • 83.55 (n)
  • 80.65 (a)
Species with no ortholog for OR1J4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1J4 Gene

ENSEMBL:
Gene Tree for OR1J4 (if available)
TreeFam:
Gene Tree for OR1J4 (if available)

Paralogs for OR1J4 Gene

Selected SIMAP similar genes for OR1J4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR1J4: view

Variants for OR1J4 Gene

Sequence variations from dbSNP and Humsavar for OR1J4 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1318392 -- 122,520,114(-) GGTCA(A/G)TACAT downstream-variant-500B
rs10120714 -- 122,518,848(+) AAGAC(A/G)TTATC upstream-variant-2KB
rs12238776 -- 122,517,222(+) TTGCA(A/G)TGCTT upstream-variant-2KB
rs34513478 -- 122,517,631(+) CTTTT(-/C)CAATT upstream-variant-2KB
rs34932994 -- 122,518,019(+) CATCC(-/C)ATGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR1J4 Gene

Variant ID Type Subtype PubMed ID
nsv893822 CNV Gain 21882294
nsv893823 CNV Loss 21882294
nsv893824 CNV Loss 21882294

Relevant External Links for OR1J4 Gene

HapMap Linkage Disequilibrium report
OR1J4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1J4 Gene

Disorders for OR1J4 Gene

No disorders were found for OR1J4 Gene.

No data available for UniProtKB/Swiss-Prot for OR1J4 Gene

Publications for OR1J4 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR1J4 Gene

Sources for OR1J4 Gene

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