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Aliases for OR1I1 Gene

Aliases for OR1I1 Gene

  • Olfactory Receptor, Family 1, Subfamily I, Member 1 2 3
  • Olfactory Receptor 19-20 3 4
  • OR19-20 3 4
  • Olfactory Receptor 1I1 3
  • OR1I1P 3
  • OR1I1Q 3

External Ids for OR1I1 Gene

Previous GeneCards Identifiers for OR1I1 Gene

  • GC19U990225
  • GC19P015059
  • GC19P015060
  • GC19P015197

Summaries for OR1I1 Gene

Entrez Gene Summary for OR1I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1I1 Gene

OR1I1 (Olfactory Receptor, Family 1, Subfamily I, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1I1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1I1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1I1 Gene

Genomics for OR1I1 Gene

Regulatory Elements for OR1I1 Gene

Genomic Location for OR1I1 Gene

Start:
15,086,980 bp from pter
End:
15,088,221 bp from pter
Size:
1,242 bases
Orientation:
Plus strand

Genomic View for OR1I1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1I1 Gene

Proteins for OR1I1 Gene

  • Protein details for OR1I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60431-OR1I1_HUMAN
    Recommended name:
    Olfactory receptor 1I1
    Protein Accession:
    O60431
    Secondary Accessions:
    • Q96R92

    Protein attributes for OR1I1 Gene

    Size:
    355 amino acids
    Molecular mass:
    39297 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1I1 Gene

Proteomics data for OR1I1 Gene at MOPED

Post-translational modifications for OR1I1 Gene

No Post-translational modifications

Other Protein References for OR1I1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1I1 Gene

Domains for OR1I1 Gene

Gene Families for OR1I1 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1I1 Gene

Suggested Antigen Peptide Sequences for OR1I1 Gene

Graphical View of Domain Structure for InterPro Entry

O60431

UniProtKB/Swiss-Prot:

OR1I1_HUMAN :
  • O60431
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1I1: view

Function for OR1I1 Gene

Molecular function for OR1I1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1I1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR1I1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1I1 Gene

Localization for OR1I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1I1 Gene COMPARTMENTS Subcellular localization image for OR1I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1I1: view

Pathways for OR1I1 Gene

genes like me logo Genes that share pathways with OR1I1: view

Pathways by source for OR1I1 Gene

1 KEGG pathway for OR1I1 Gene

Interacting Proteins for OR1I1 Gene

Gene Ontology (GO) - Biological Process for OR1I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1I1: view

Transcripts for OR1I1 Gene

mRNA/cDNA for OR1I1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR1I1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR1I1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR1I1 Gene

No ASD Table

Relevant External Links for OR1I1 Gene

GeneLoc Exon Structure for
OR1I1
ECgene alternative splicing isoforms for
OR1I1

Expression for OR1I1 Gene

mRNA expression in normal human tissues for OR1I1 Gene

SOURCE GeneReport for Unigene cluster for OR1I1 Gene Hs.631610

genes like me logo Genes that share expressions with OR1I1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR1I1 Gene

Orthologs for OR1I1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1I1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 77 (a)
OneToMany
-- 36
  • 73 (a)
OneToMany
dog
(Canis familiaris)
Mammalia OR1I1 35
  • 83.6 (n)
  • 81.76 (a)
mouse
(Mus musculus)
Mammalia Olfr1357 35
  • 80.56 (n)
  • 77.2 (a)
Olfr1357 16
Olfr1357 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR1I1 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1087 35
  • 80.35 (n)
  • 76.22 (a)
Species with no ortholog for OR1I1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1I1 Gene

ENSEMBL:
Gene Tree for OR1I1 (if available)
TreeFam:
Gene Tree for OR1I1 (if available)

Paralogs for OR1I1 Gene

Selected SIMAP similar genes for OR1I1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR1I1: view

Variants for OR1I1 Gene

Sequence variations from dbSNP and Humsavar for OR1I1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs8104843 - 15,087,481(+) CTCCC(C/G)TGTCT reference, missense
rs8104900 -- 15,086,969(+) CAGTA(C/T)AGGTT upstream-variant-2KB
rs8105277 -- 15,087,452(+) CACCC(A/G)CAGCG reference, synonymous-codon
rs8105737 - 15,087,820(+) GTCCT(A/C)TGGGA reference, missense
rs8108721 - 15,087,696(+) GCCCA(C/T)TCTCC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR1I1 Gene

Variant ID Type Subtype PubMed ID
dgv1058e1 CNV Complex 17122850
nsv525115 CNV Loss 19592680

Relevant External Links for OR1I1 Gene

HapMap Linkage Disequilibrium report
OR1I1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1I1 Gene

Disorders for OR1I1 Gene

No disorders were found for OR1I1 Gene.

No data available for UniProtKB/Swiss-Prot for OR1I1 Gene

Publications for OR1I1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR1I1 Gene

Sources for OR1I1 Gene

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