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Aliases for OR1F12 Gene

Aliases for OR1F12 Gene

  • Olfactory Receptor Family 1 Subfamily F Member 12 2 3 5
  • Olfactory Receptor, Family 1, Subfamily F, Member 12 Pseudogene 2 3
  • Hs6M1-35P 3 4
  • OR1F12P 3 4
  • Olfactory Receptor, Family 1, Subfamily F, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 1, Subfamily F, Member 12 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor OR6-12 3
  • OR1F12Q 3
  • OR6-12 3

External Ids for OR1F12 Gene

Previous HGNC Symbols for OR1F12 Gene

  • OR1F12P

Previous GeneCards Identifiers for OR1F12 Gene

  • GC00U990906
  • GC06P028148
  • GC06P028044

Summaries for OR1F12 Gene

Entrez Gene Summary for OR1F12 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1F12 Gene

OR1F12 (Olfactory Receptor Family 1 Subfamily F Member 12) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR1F12 Gene

  • Odorant receptor.

Additional gene information for OR1F12 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1F12 Gene

Genomics for OR1F12 Gene

Regulatory Elements for OR1F12 Gene

Enhancers for OR1F12 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H028079 1.2 ENCODE 0.4 +7.4 7418 3 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D ZNF603P ZKSCAN8 ZKSCAN3 ZSCAN12 ZSCAN9 OR2B8P ZKSCAN4 ZNF311 PGBD1 ZSCAN26
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR1F12 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR1F12 Gene

Chromosome:
6
Start:
28,073,248 bp from pter
End:
28,074,260 bp from pter
Size:
1,013 bases
Orientation:
Plus strand

Genomic View for OR1F12 Gene

Genes around OR1F12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1F12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1F12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1F12 Gene

Proteins for OR1F12 Gene

  • Protein details for OR1F12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHA8-OR1FC_HUMAN
    Recommended name:
    Olfactory receptor 1F12
    Protein Accession:
    Q8NHA8

    Protein attributes for OR1F12 Gene

    Size:
    337 amino acids
    Molecular mass:
    36933 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1F12 Gene

Post-translational modifications for OR1F12 Gene

  • Glycosylation at Asn5, posLast=88, and posLast=265265

Other Protein References for OR1F12 Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR1F12 Gene

Domains & Families for OR1F12 Gene

Gene Families for OR1F12 Gene

Protein Domains for OR1F12 Gene

Suggested Antigen Peptide Sequences for OR1F12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NHA8

UniProtKB/Swiss-Prot:

OR1FC_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1F12: view

Function for OR1F12 Gene

Molecular function for OR1F12 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR1F12 Gene

Gene Ontology (GO) - Molecular Function for OR1F12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1F12: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for OR1F12
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1F12 Gene

Localization for OR1F12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1F12 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR1F12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1F12: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR1F12 Gene

Pathways & Interactions for OR1F12 Gene

genes like me logo Genes that share pathways with OR1F12: view

Pathways by source for OR1F12 Gene

Interacting Proteins for OR1F12 Gene

Gene Ontology (GO) - Biological Process for OR1F12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1F12: view

No data available for SIGNOR curated interactions for OR1F12 Gene

Drugs & Compounds for OR1F12 Gene

No Compound Related Data Available

Transcripts for OR1F12 Gene

mRNA/cDNA for OR1F12 Gene

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for OR1F12
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OR1F12 Gene

No ASD Table

Relevant External Links for OR1F12 Gene

GeneLoc Exon Structure for
OR1F12
ECgene alternative splicing isoforms for
OR1F12

Expression for OR1F12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR1F12 Gene

mRNA differential expression in normal tissues according to GTEx for OR1F12 Gene

This gene is overexpressed in Testis (x10.3).

NURSA nuclear receptor signaling pathways regulating expression of OR1F12 Gene:

OR1F12
genes like me logo Genes that share expression patterns with OR1F12: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR1F12 Gene

Orthologs for OR1F12 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR1F12 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Or1f12 52 Olfr1366
  • chr13:21,537,020-21,538,063
Species where no ortholog for OR1F12 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1F12 Gene

ENSEMBL:
Gene Tree for OR1F12 (if available)
TreeFam:
Gene Tree for OR1F12 (if available)

Paralogs for OR1F12 Gene

(460) SIMAP similar genes for OR1F12 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with OR1F12: view

No data available for Paralogs for OR1F12 Gene

Variants for OR1F12 Gene

Relevant External Links for OR1F12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR1F12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR1F12 Gene

Disorders for OR1F12 Gene

No disorders were found for OR1F12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR1F12 Gene

Publications for OR1F12 Gene

  1. Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism. (PMID: 25464930) Shen C … Zhong N (Journal of molecular neuroscience : MN 2015) 3 60
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 60

Products for OR1F12 Gene

Sources for OR1F12 Gene

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