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Aliases for OR1E3 Gene

Aliases for OR1E3 Gene

  • Olfactory Receptor Family 1 Subfamily E Member 3 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 1, Subfamily E, Member 3 Pseudogene 2 3
  • Olfactory Receptor 17-210 3 4
  • OR17-210 3 4
  • OR1E3P 3 4
  • Olfactory Receptor, Family 1, Subfamily E, Member 3 (Gene/Pseudogene) 2
  • Seven Transmembrane Helices Olfactory Receptor 3
  • Olfactory Receptor OR17-7 4
  • OLFR 17-210 3

External Ids for OR1E3 Gene

Previous HGNC Symbols for OR1E3 Gene

  • OR1E3P

Previous GeneCards Identifiers for OR1E3 Gene

  • GC17P002967

Summaries for OR1E3 Gene

Entrez Gene Summary for OR1E3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1E3 Gene

OR1E3 (Olfactory Receptor Family 1 Subfamily E Member 3 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR1E3 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1E3 Gene

Genomics for OR1E3 Gene

Regulatory Elements for OR1E3 Gene

Enhancers for OR1E3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F003001 1 Ensembl ENCODE 16.3 -112.8 -112828 4.8 WRNIP1 SIN3A BRCA1 ZNF2 YY1 GLIS2 ZHX2 REST TBX21 MBD2 OR1D5 OR1D2 OR1E3 OR1D3P OR3A4P SAMD11P1 EIF4A1P9 OR1E2 ENSG00000262869 RAP1GAP2
GH17F002847 1.1 FANTOM5 Ensembl ENCODE 16.2 -267.9 -267930 2.6 ELF3 ZFP64 INSM2 KLF17 SIN3A ZNF48 ZNF2 RAD21 ZEB1 GLIS2 HNRNPA1P16 METTL16 ENSG00000263345 LOC105371492 OR1D5 SAMD11P1 OR1D2 OR1E3 EIF4A1P9 OR1D3P
GH17F002924 1.2 Ensembl ENCODE 16.2 -190.9 -190906 2.6 INSM2 ZNF76 SIN3A KLF17 GLI4 ZNF2 RAD21 ZNF366 ZNF143 ZNF391 OR1D5 OR1D2 OR1E3 SAMD11P1 EIF4A1P9 OR1D3P OR3A4P OR1E2 ENSG00000262869 LOC105371492
GH17F003988 1.1 Ensembl ENCODE 16.2 +872.6 872612 1.1 ATF1 PKNOX1 SIN3A GLI4 ZNF2 ZNF121 GLIS2 ZNF416 KLF7 ZNF548 OR1E2 OR3A4P OR1E3 OR1D3P OR1D2 OR1D5 SHPK LOC101927979 CYB5D2 ZZEF1
GH17F003986 0.6 Ensembl 16.2 +870.3 870278 1.0 ZNF133 SIN3A GLI4 FEZF1 ZNF2 ZNF121 GLIS2 ZNF302 KLF7 ZNF548 OR1E2 OR3A4P OR1D2 OR1E3 OR1D3P OR1D5 SHPK LOC105371492 CYB5D2 GC17M003989
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR1E3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR1E3 Gene

Chromosome:
17
Start:
3,116,423 bp from pter
End:
3,117,374 bp from pter
Size:
952 bases
Orientation:
Plus strand

Genomic View for OR1E3 Gene

Genes around OR1E3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1E3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1E3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1E3 Gene

Proteins for OR1E3 Gene

  • Protein details for OR1E3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WZA6-OR1E3_HUMAN
    Recommended name:
    Olfactory receptor 1E3
    Protein Accession:
    Q8WZA6

    Protein attributes for OR1E3 Gene

    Size:
    343 amino acids
    Molecular mass:
    38518 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1E3 Gene

Post-translational modifications for OR1E3 Gene

No data available for DME Specific Peptides for OR1E3 Gene

Domains & Families for OR1E3 Gene

Gene Families for OR1E3 Gene

Protein Domains for OR1E3 Gene

Suggested Antigen Peptide Sequences for OR1E3 Gene

Graphical View of Domain Structure for InterPro Entry

Q8WZA6

UniProtKB/Swiss-Prot:

OR1E3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1E3: view

Function for OR1E3 Gene

Molecular function for OR1E3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1E3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1E3: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1E3 Gene

Localization for OR1E3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1E3 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR1E3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1E3: view

No data available for Subcellular locations from COMPARTMENTS for OR1E3 Gene

Pathways & Interactions for OR1E3 Gene

genes like me logo Genes that share pathways with OR1E3: view

Pathways by source for OR1E3 Gene

1 BioSystems pathway for OR1E3 Gene

Interacting Proteins for OR1E3 Gene

Gene Ontology (GO) - Biological Process for OR1E3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1E3: view

No data available for SIGNOR curated interactions for OR1E3 Gene

Transcripts for OR1E3 Gene

mRNA/cDNA for OR1E3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1E3 Gene

No ASD Table

Relevant External Links for OR1E3 Gene

GeneLoc Exon Structure for
OR1E3
ECgene alternative splicing isoforms for
OR1E3

Expression for OR1E3 Gene

mRNA expression in normal human tissues for OR1E3 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR1E3 Gene:

OR1E3
genes like me logo Genes that share expression patterns with OR1E3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR1E3 Gene

Orthologs for OR1E3 Gene

Evolution for OR1E3 Gene

ENSEMBL:
Gene Tree for OR1E3 (if available)
TreeFam:
Gene Tree for OR1E3 (if available)

No data available for Orthologs for OR1E3 Gene

Paralogs for OR1E3 Gene

(456) SIMAP similar genes for OR1E3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1E3: view

No data available for Paralogs for OR1E3 Gene

Variants for OR1E3 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR1E3 Gene

OR1E3_HUMAN-Q8WZA6
A single nucleotide deletion at position Leu-17 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene.

Relevant External Links for OR1E3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR1E3

No data available for Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR1E3 Gene

Disorders for OR1E3 Gene

No disorders were found for OR1E3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR1E3 Gene

Publications for OR1E3 Gene

  1. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 2 3 4 64
  2. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PMID: 8004088) Ben-Arie N. … North M.A. (Hum. Mol. Genet. 1994) 2 3 4 64
  3. [Functional diversity of seven-transmembrane olfactory receptors in olfactory signal transduction systems]. (PMID: 19068743) Sato K. … Touhara K. (Tanpakushitsu Kakusan Koso 2008) 22 64
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4 64
  5. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 4 64

Products for OR1E3 Gene

Sources for OR1E3 Gene

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