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Aliases for OR1E1 Gene

Aliases for OR1E1 Gene

  • Olfactory Receptor, Family 1, Subfamily E, Member 1 2 3
  • Olfactory Receptor-Like Protein HGMP07I 3 4
  • Olfactory Receptor 17-2/17-32 3 4
  • Olfactory Receptor OR17-18 3 4
  • Olfactory Receptor 13-66 3 4
  • Olfactory Receptor 5-85 3 4
  • Olfactory Receptor 1E5 3 4
  • Olfactory Receptor 1E6 3 4
  • OR13-66 3 4
  • OR17-32 3 4
  • OR17-2 3 4
  • OR1E9P 3 4
  • OR5-85 3 4
  • OR1E5 3 4
  • OR1E6 3 4
  • Olfactory Receptor, Family 1, Subfamily E, Member 8 Pseudogene 3
  • Olfactory Receptor, Family 1, Subfamily E, Member 9 Pseudogene 3
  • Olfactory Receptor, Family 1, Subfamily E, Member 5 3
  • Olfactory Receptor, Family 1, Subfamily E, Member 6 3
  • Olfactory Receptor OR17-4 3
  • Olfactory Receptor 1E1 3
  • HGM071 3
  • OR1E8P 3
  • OST547 3

External Ids for OR1E1 Gene

Previous Symbols for OR1E1 Gene

  • OR1E9P
  • OR1E5
  • OR1E6

Summaries for OR1E1 Gene

Entrez Gene Summary for OR1E1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1E1 Gene

OR1E1 (Olfactory Receptor, Family 1, Subfamily E, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1E2.

UniProtKB/Swiss-Prot for OR1E1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1E1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1E1 Gene

Genomics for OR1E1 Gene

Genomic Location for OR1E1 Gene

Start:
3,397,104 bp from pter
End:
3,398,410 bp from pter
Size:
1,307 bases
Orientation:
Minus strand

Genomic View for OR1E1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1E1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1E1 Gene

Regulatory Elements for OR1E1 Gene

Proteins for OR1E1 Gene

  • Protein details for OR1E1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P30953-OR1E1_HUMAN
    Recommended name:
    Olfactory receptor 1E1
    Protein Accession:
    P30953
    Secondary Accessions:
    • O43884
    • P47882
    • P47885
    • Q6IFA9
    • Q6IFM5
    • Q9UBJ1
    • Q9UM60

    Protein attributes for OR1E1 Gene

    Size:
    314 amino acids
    Molecular mass:
    35264 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1E1 Gene

Proteomics data for OR1E1 Gene at MOPED

Post-translational modifications for OR1E1 Gene

Other Protein References for OR1E1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR1E1 Gene

Domains for OR1E1 Gene

Gene Families for OR1E1 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1E1 Gene

Suggested Antigen Peptide Sequences for OR1E1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P30953

UniProtKB/Swiss-Prot:

OR1E1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • P30953
genes like me logo Genes that share domains with OR1E1: view

Function for OR1E1 Gene

Molecular function for OR1E1 Gene

GENATLAS Biochemistry: olfactory receptor,family 1,subfamily E,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 1370859
genes like me logo Genes that share ontologies with OR1E1: view

Phenotypes for OR1E1 Gene

GenomeRNAi human phenotypes for OR1E1:
genes like me logo Genes that share phenotypes with OR1E1: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1E1 Gene

Localization for OR1E1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1E1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1E1 Gene COMPARTMENTS Subcellular localization image for OR1E1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1E1: view

Pathways for OR1E1 Gene

genes like me logo Genes that share pathways with OR1E1: view

Pathways by source for OR1E1 Gene

1 KEGG pathway for OR1E1 Gene

Interacting Proteins for OR1E1 Gene

Gene Ontology (GO) - Biological Process for OR1E1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 1370859
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 1370859
genes like me logo Genes that share ontologies with OR1E1: view

Transcripts for OR1E1 Gene

mRNA/cDNA for OR1E1 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR1E1 Gene

Olfactory receptor, family 1, subfamily E, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR1E1 Gene

No ASD Table

Relevant External Links for OR1E1 Gene

GeneLoc Exon Structure for
OR1E1
ECgene alternative splicing isoforms for
OR1E1

Expression for OR1E1 Gene

mRNA expression in normal human tissues for OR1E1 Gene

mRNA differential expression in normal tissues according to GTEx for OR1E1 Gene

This gene is overexpressed in Muscle - Skeletal (5.1) and Testis (4.9).

SOURCE GeneReport for Unigene cluster for OR1E1 Gene Hs.278485

genes like me logo Genes that share expressions with OR1E1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for OR1E1 Gene

Orthologs for OR1E1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1E1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR1E1 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 83 (a)
ManyToMany
-- 36
  • 82 (a)
ManyToMany
-- 36
  • 82 (a)
ManyToMany
-- 36
  • 81 (a)
ManyToMany
-- 36
  • 82 (a)
ManyToMany
-- 36
  • 83 (a)
ManyToMany
-- 36
  • 83 (a)
ManyToMany
LOC615901 35
  • 86.41 (n)
  • 83.12 (a)
dog
(Canis familiaris)
Mammalia DTMT 36
  • 83 (a)
ManyToMany
LOC100683843 35
  • 87.03 (n)
  • 84.89 (a)
OR1E2 36
  • 84 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr1 36
  • 80 (a)
ManyToMany
Olfr20 16
Olfr20 36
  • 84 (a)
ManyToMany
Olfr23 36
  • 73 (a)
ManyToMany
Olfr376 36
  • 81 (a)
ManyToMany
Olfr378 36
  • 75 (a)
ManyToMany
Olfr380 36
  • 72 (a)
ManyToMany
Olfr381 36
  • 72 (a)
ManyToMany
Olfr382 36
  • 72 (a)
ManyToMany
Olfr384 36
  • 73 (a)
ManyToMany
Olfr385 36
  • 71 (a)
ManyToMany
Olfr389 36
  • 76 (a)
ManyToMany
Olfr390 36
  • 77 (a)
ManyToMany
Olfr392 36
  • 76 (a)
ManyToMany
Olfr393 36
  • 74 (a)
ManyToMany
Olfr394 36
  • 75 (a)
ManyToMany
Olfr395 36
  • 76 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia OPOR52 36
  • 75 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1468 35
  • 82.8 (n)
  • 79.62 (a)
Species with no ortholog for OR1E1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1E1 Gene

ENSEMBL:
Gene Tree for OR1E1 (if available)
TreeFam:
Gene Tree for OR1E1 (if available)

Paralogs for OR1E1 Gene

Selected SIMAP similar genes for OR1E1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR1E1 Gene

genes like me logo Genes that share paralogs with OR1E1: view

Variants for OR1E1 Gene

Sequence variations from dbSNP and Humsavar for OR1E1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs150988 -- 3,398,255(+) TGGGA(A/G)TCCAG reference, synonymous-codon
rs150989 - 3,397,984(+) CAGGG(A/C/T)GAGAC missense, reference
rs226357 -- 3,399,694(+) cccta(A/G)accag upstream-variant-2KB
rs226358 -- 3,399,354(-) TGTTT(C/G)TTTCT upstream-variant-2KB
rs379147 -- 3,397,845(+) CAGAG(A/C)AGGCC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR1E1 Gene

Variant ID Type Subtype PubMed ID
esv2660206 CNV Deletion 23128226
nsv907553 CNV Loss 21882294
nsv833341 CNV Loss 17160897
nsv521277 CNV Gain 19592680

Relevant External Links for OR1E1 Gene

HapMap Linkage Disequilibrium report
OR1E1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1E1 Gene

Disorders for OR1E1 Gene

(1) University of Copenhagen DISEASES for OR1E1 Gene

Relevant External Links for OR1E1

Genetic Association Database (GAD)
OR1E1
Human Genome Epidemiology (HuGE) Navigator
OR1E1
genes like me logo Genes that share disorders with OR1E1: view

No data available for UniProtKB/Swiss-Prot for OR1E1 Gene

Publications for OR1E1 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3 4
  2. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PMID: 8004088) Ben-Arie N. … North M.A. (Hum. Mol. Genet. 1994) 2 3 4
  3. Distribution of olfactory receptor genes in the human genome. (PMID: 9500546) Rouquier S. … Giorgi D. (Nat. Genet. 1998) 3 4
  4. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 3 4
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4

Products for OR1E1 Gene

Sources for OR1E1 Gene

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