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Aliases for OR1D5 Gene

Aliases for OR1D5 Gene

  • Olfactory Receptor, Family 1, Subfamily D, Member 5 2 3
  • Olfactory Receptor 17-31 3 4
  • OR17-31 3 4
  • Olfactory Receptor OR17-2 3
  • Olfactory Receptor 1D5 3
  • OR17-30 3
  • C17orf2 3
  • OR17-2 3

External Ids for OR1D5 Gene

Summaries for OR1D5 Gene

Entrez Gene Summary for OR1D5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1D5 Gene

OR1D5 (Olfactory Receptor, Family 1, Subfamily D, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1L4.

UniProtKB/Swiss-Prot for OR1D5 Gene

  • Odorant receptor.

Gene Wiki entry for OR1D5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1D5 Gene

Genomics for OR1D5 Gene

Genomic Location for OR1D5 Gene

Start:
3,062,669 bp from pter
End:
3,063,607 bp from pter
Size:
939 bases
Orientation:
Minus strand

Genomic View for OR1D5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1D5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1D5 Gene

Regulatory Elements for OR1D5 Gene

Proteins for OR1D5 Gene

  • Protein details for OR1D5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P58170-OR1D5_HUMAN
    Recommended name:
    Olfactory receptor 1D5
    Protein Accession:
    P58170
    Secondary Accessions:
    • Q96RA6

    Protein attributes for OR1D5 Gene

    Size:
    312 amino acids
    Molecular mass:
    35424 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1D5 Gene

Proteomics data for OR1D5 Gene at MOPED

Post-translational modifications for OR1D5 Gene

Other Protein References for OR1D5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR1D5 Gene

Domains for OR1D5 Gene

Gene Families for OR1D5 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1D5 Gene

Suggested Antigen Peptide Sequences for OR1D5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P58170

UniProtKB/Swiss-Prot:

OR1D5_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • P58170
genes like me logo Genes that share domains with OR1D5: view

Function for OR1D5 Gene

Molecular function for OR1D5 Gene

GENATLAS Biochemistry: olfactory receptor,family 1,subfamily D,member 5,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1D5: view

Phenotypes for OR1D5 Gene

GenomeRNAi human phenotypes for OR1D5:
genes like me logo Genes that share phenotypes with OR1D5: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1D5 Gene

Localization for OR1D5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1D5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR1D5: view

No data available for Subcellular locations from COMPARTMENTS for OR1D5 Gene

Pathways for OR1D5 Gene

genes like me logo Genes that share pathways with OR1D5: view

Pathways by source for OR1D5 Gene

1 KEGG pathway for OR1D5 Gene

Interacting Proteins for OR1D5 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000459028%0d%0a9606.ENSP00000334051%0d%0a9606.ENSP00000269260%0d%0a9606.ENSP00000317578%0d%0a
Selected Interacting proteins: ENSP00000459028 for OR1D5 Gene via STRING

Gene Ontology (GO) - Biological Process for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell TAS 1315913
GO:0050911 detection of chemical stimulus involved in sensory perception of smell TAS 1315913
genes like me logo Genes that share ontologies with OR1D5: view

Transcripts for OR1D5 Gene

mRNA/cDNA for OR1D5 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1D5 Gene

No ASD Table

Relevant External Links for OR1D5 Gene

GeneLoc Exon Structure for
OR1D5
ECgene alternative splicing isoforms for
OR1D5

Expression for OR1D5 Gene

mRNA expression in normal human tissues for OR1D5 Gene

SOURCE GeneReport for Unigene cluster for OR1D5 Gene Hs.553508

genes like me logo Genes that share expressions with OR1D5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR1D5 Gene

Orthologs for OR1D5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR1D5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC468150 35
  • 98.72 (n)
  • 97.12 (a)
OR1D5 36
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 75 (a)
ManyToMany
-- 36
  • 76 (a)
ManyToMany
OR1D5 35
  • 84.73 (n)
  • 79.68 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 80 (a)
OneToMany
cOR1D8 35
  • 84.84 (n)
  • 79.35 (a)
mouse
(Mus musculus)
Mammalia Olfr412 36
  • 80 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 41 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
Species with no ortholog for OR1D5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1D5 Gene

ENSEMBL:
Gene Tree for OR1D5 (if available)
TreeFam:
Gene Tree for OR1D5 (if available)

Paralogs for OR1D5 Gene

Paralogs for OR1D5 Gene

Selected SIMAP similar genes for OR1D5 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR1D5 Gene

genes like me logo Genes that share paralogs with OR1D5: view

Variants for OR1D5 Gene

Sequence variations from dbSNP and Humsavar for OR1D5 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2014261 -- 3,065,060(-) TAGTA(C/T)GTTTG upstream-variant-2KB
rs2676565 -- 3,062,879(+) AAATG(C/G/T)GAGGC synonymous-codon, reference
rs2676566 -- 3,062,897(+) GAGAA(A/G)GTTTT reference, synonymous-codon
rs2676567 -- 3,062,979(+) CTAAG(A/G)GGGTG reference, missense
rs2855605 -- 3,063,014(-) ACAGC(A/G)TTGAT synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for OR1D5 Gene

Variant ID Type Subtype PubMed ID
esv2660206 CNV Deletion 23128226
nsv7288 OTHER Inversion 18451855
nsv907552 CNV Loss 21882294

Relevant External Links for OR1D5 Gene

HapMap Linkage Disequilibrium report
OR1D5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1D5 Gene

Disorders for OR1D5 Gene

No disorders were found for OR1D5 Gene.

No data available for UniProtKB/Swiss-Prot for OR1D5 Gene

Publications for OR1D5 Gene

  1. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 2 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  5. Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences. (PMID: 1315913) Selbie L.A. … Shine J. (Brain Res. Mol. Brain Res. 1992) 3

Products for OR1D5 Gene

Sources for OR1D5 Gene

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