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Aliases for OR1D5 Gene

Aliases for OR1D5 Gene

  • Olfactory Receptor Family 1 Subfamily D Member 5 2 3 5
  • Olfactory Receptor 17-31 3 4
  • OR17-31 3 4
  • Olfactory Receptor, Family 1, Subfamily D, Member 5 2
  • Olfactory Receptor OR17-2 3
  • Olfactory Receptor 1D5 3
  • OR17-30 3
  • C17orf2 3
  • OR17-2 3
  • OR1D4 3

External Ids for OR1D5 Gene

Previous GeneCards Identifiers for OR1D5 Gene

  • GC17M003280
  • GC17U900018
  • GC17M003173
  • GC17M003174
  • GC17M002912
  • GC17M002965

Summaries for OR1D5 Gene

Entrez Gene Summary for OR1D5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1D5 Gene

OR1D5 (Olfactory Receptor Family 1 Subfamily D Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR1D2.

UniProtKB/Swiss-Prot for OR1D5 Gene

  • Odorant receptor.

Gene Wiki entry for OR1D5 Gene

Additional gene information for OR1D5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1D5 Gene

Genomics for OR1D5 Gene

Regulatory Elements for OR1D5 Gene

Enhancers for OR1D5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H002390 1.9 FANTOM5 ENCODE dbSUPER 14.6 +664.6 664596 18.6 MLX FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC SSRP1 ZNF610 ZNF585B METTL16 PRPF8 SMYD4 HNRNPA1P16 SMG6 MNT TSR1 ENSG00000263345 SGSM2 RPA1
GH17H002847 1.7 FANTOM5 Ensembl ENCODE dbSUPER 14.6 +214.8 214786 1.9 ELF3 INSM2 KLF17 SIN3A ZNF2 RAD21 ZEB1 GLIS2 ZNF366 ZNF143 OR1D5 SAMD11P1 OR1D2 EIF4A1P9 OR1E3 OR1D3P OR3A4P OR1E2 ENSG00000262869 PAFAH1B1
GH17H003885 1.7 FANTOM5 ENCODE dbSUPER 14.6 -826.9 -826930 10.9 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ZNF302 ZNF416 ANKFY1 MYBBP1A PELP1 ENSG00000235085 LOC105371492 ZZEF1 P2RX1 OR1E2 OR3A4P OR1E3
GH17H003001 1.5 Ensembl ENCODE dbSUPER 14.8 +59.8 59759 4.3 FOXA2 SIN3A BRCA1 ZNF2 YY1 GLIS2 ATF7 RUNX3 REST ZNF610 OR1D5 OR1D2 OR1E3 OR1D3P OR3A4P SAMD11P1 EIF4A1P9 OR1E2 ENSG00000262869 RAP1GAP2
GH17H002924 1.4 Ensembl ENCODE dbSUPER 14.7 +138.1 138090 2.6 INSM2 ZNF76 KLF17 GLI4 ZNF366 ATF7 EGR2 YY2 ZNF114 ZNF662 METTL16 SMG6 HNRNPA1P16 LOC105371492 OR1D5 OR1D2 OR1E3 SAMD11P1 EIF4A1P9 OR1D3P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR1D5 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OR1D5 Gene

Genomic Locations for OR1D5 Gene
939 bases
Minus strand

Genomic View for OR1D5 Gene

Genes around OR1D5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1D5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1D5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1D5 Gene

Proteins for OR1D5 Gene

  • Protein details for OR1D5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 1D5
    Protein Accession:
    Secondary Accessions:
    • Q96RA6

    Protein attributes for OR1D5 Gene

    312 amino acids
    Molecular mass:
    35424 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1D5 Gene

Post-translational modifications for OR1D5 Gene

No Post-translational modifications

Other Protein References for OR1D5 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1D5 Gene

Domains & Families for OR1D5 Gene

Gene Families for OR1D5 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR1D5 Gene

Suggested Antigen Peptide Sequences for OR1D5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1D5: view

Function for OR1D5 Gene

Molecular function for OR1D5 Gene

GENATLAS Biochemistry:
olfactory receptor,family 1,subfamily D,member 5,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR1D5 Gene

Gene Ontology (GO) - Molecular Function for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA,TAS --
GO:0004984 olfactory receptor activity IBA,TAS --
genes like me logo Genes that share ontologies with OR1D5: view
genes like me logo Genes that share phenotypes with OR1D5: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1D5 Gene

Localization for OR1D5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1D5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR1D5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1D5: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR1D5 Gene

Pathways & Interactions for OR1D5 Gene

genes like me logo Genes that share pathways with OR1D5: view

Pathways by source for OR1D5 Gene

1 KEGG pathway for OR1D5 Gene

Interacting Proteins for OR1D5 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 12)
Selected Interacting proteins: ENSP00000459028 P58170-OR1D5_HUMAN for OR1D5 Gene via STRING IID

Gene Ontology (GO) - Biological Process for OR1D5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS,IBA --
GO:0007608 sensory perception of smell TAS 1315913
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR1D5: view

No data available for SIGNOR curated interactions for OR1D5 Gene

Drugs & Compounds for OR1D5 Gene

No Compound Related Data Available

Transcripts for OR1D5 Gene

mRNA/cDNA for OR1D5 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR1D5 Gene

No ASD Table

Relevant External Links for OR1D5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR1D5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR1D5 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR1D5 Gene:


SOURCE GeneReport for Unigene cluster for OR1D5 Gene:

genes like me logo Genes that share expression patterns with OR1D5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR1D5 Gene

Orthologs for OR1D5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR1D5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC468150 33
  • 98.72 (n)
OR1D5 34
  • 95 (a)
(Canis familiaris)
Mammalia cOR1D8 33
  • 84.84 (n)
-- 34
  • 80 (a)
(Bos Taurus)
Mammalia OR1D5 33
  • 84.73 (n)
-- 34
  • 76 (a)
-- 34
  • 75 (a)
(Mus musculus)
Mammalia Olfr412 34
  • 80 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 41 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 47 (a)
-- 34
  • 47 (a)
-- 34
  • 47 (a)
-- 34
  • 41 (a)
Species where no ortholog for OR1D5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1D5 Gene

Gene Tree for OR1D5 (if available)
Gene Tree for OR1D5 (if available)

Paralogs for OR1D5 Gene

(451) SIMAP similar genes for OR1D5 Gene using alignment to 2 proteins: Pseudogenes for OR1D5 Gene

genes like me logo Genes that share paralogs with OR1D5: view

Variants for OR1D5 Gene

Sequence variations from dbSNP and Humsavar for OR1D5 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1001165709 -- 3,063,835(+) TATTA(C/T)AAAAA upstream-variant-2KB
rs1001263129 -- 3,063,412(+) GGAGA(A/G)GTTGG reference, missense
rs1003105843 -- 3,064,040(+) TTATT(A/G)CTTGT upstream-variant-2KB
rs1005005621 -- 3,064,557(+) AAACA(C/T)ATTAT upstream-variant-2KB
rs1008933160 -- 3,062,424(+) ATCAA(A/G)CAGGT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR1D5 Gene

Variant ID Type Subtype PubMed ID
dgv3084n100 CNV loss 25217958
esv2660206 CNV deletion 23128226
nsv962245 CNV duplication 23825009
nsv7288 OTHER inversion 18451855
nsv1065489 CNV gain 25217958

Variation tolerance for OR1D5 Gene

Residual Variation Intolerance Score: 84.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.81; 89.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR1D5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR1D5 Gene

Disorders for OR1D5 Gene

Relevant External Links for OR1D5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR1D5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1D5 Gene

Publications for OR1D5 Gene

  1. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G … Lancet D (Genomics 2000) 2 3 4 60
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 60
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60
  5. Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences. (PMID: 1315913) Selbie LA … Shine J (Brain research. Molecular brain research 1992) 3 60

Products for OR1D5 Gene

Sources for OR1D5 Gene

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