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Aliases for OR1D4 Gene

Aliases for OR1D4 Gene

  • Olfactory Receptor, Family 1, Subfamily D, Member 4 (Gene/Pseudogene) 2 3
  • Olfactory Receptor 17-30 3 4
  • OR17-30 3 4
  • Olfactory Receptor, Family 1, Subfamily D, Member 4 Pseudogene 3
  • Olfactory Receptor, Family 1, Subfamily D, Member 4 2
  • Olfactory Receptor Pseudogene 3
  • Olfactory Receptor OR17-1 3
  • Olfactory Receptor 1D4 3

External Ids for OR1D4 Gene

Summaries for OR1D4 Gene

Entrez Gene Summary for OR1D4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2010]

GeneCards Summary for OR1D4 Gene

OR1D4 (Olfactory Receptor, Family 1, Subfamily D, Member 4 (Gene/Pseudogene)) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR1D4 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1D4 Gene

Genomics for OR1D4 Gene

Genomic Location for OR1D4 Gene

Start:
3,240,676 bp from pter
End:
3,241,614 bp from pter
Size:
939 bases
Orientation:
Plus strand

Genomic View for OR1D4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1D4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1D4 Gene

Regulatory Elements for OR1D4 Gene

Proteins for OR1D4 Gene

  • Protein details for OR1D4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P47884-OR1D4_HUMAN
    Recommended name:
    Olfactory receptor 1D4
    Protein Accession:
    P47884
    Secondary Accessions:
    • Q96RA5
    • Q9UM75

    Protein attributes for OR1D4 Gene

    Size:
    311 amino acids
    Molecular mass:
    35227 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1D4 Gene

Proteomics data for OR1D4 Gene at MOPED

Post-translational modifications for OR1D4 Gene

Other Protein References for OR1D4 Gene

Reactome Protein details:

No data available for DME Specific Peptides for OR1D4 Gene

Domains for OR1D4 Gene

Gene Families for OR1D4 Gene

HGNC:
  • OR1 :GPCR / Class A : Olfactory receptors

Protein Domains for OR1D4 Gene

UniProtKB/Swiss-Prot:

OR1D4_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • P47884
genes like me logo Genes that share domains with OR1D4: view

Function for OR1D4 Gene

Molecular function for OR1D4 Gene

GENATLAS Biochemistry: olfactory receptor,family 1,subfamily D,member 4,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1D4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1D4: view

Phenotypes for OR1D4 Gene

GenomeRNAi human phenotypes for OR1D4:
genes like me logo Genes that share phenotypes with OR1D4: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR1D4 Gene

Localization for OR1D4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1D4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR1D4 Gene COMPARTMENTS Subcellular localization image for OR1D4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1D4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane TAS 8004088
genes like me logo Genes that share ontologies with OR1D4: view

Pathways for OR1D4 Gene

SuperPathways for OR1D4 Gene

No Data Available

Interacting Proteins for OR1D4 Gene

Gene Ontology (GO) - Biological Process for OR1D4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007606 sensory perception of chemical stimulus TAS 8004088
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1D4: view

No data available for Pathways by source for OR1D4 Gene

Transcripts for OR1D4 Gene

mRNA/cDNA for OR1D4 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1D4 Gene

No ASD Table

Relevant External Links for OR1D4 Gene

GeneLoc Exon Structure for
OR1D4
ECgene alternative splicing isoforms for
OR1D4

Expression for OR1D4 Gene

mRNA expression in normal human tissues for OR1D4 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR1D4 Gene

SOURCE GeneReport for Unigene cluster for OR1D4 Gene Hs.653087

genes like me logo Genes that share expressions with OR1D4: view

Orthologs for OR1D4 Gene

Evolution for OR1D4 Gene

ENSEMBL:
Gene Tree for OR1D4 (if available)
TreeFam:
Gene Tree for OR1D4 (if available)

No data available for Orthologs for OR1D4 Gene

Paralogs for OR1D4 Gene

Selected SIMAP similar genes for OR1D4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1D4: view

No data available for Paralogs for OR1D4 Gene

Variants for OR1D4 Gene

Sequence variations from dbSNP and Humsavar for OR1D4 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2515743 -- 3,240,077(+) CACAG(A/G)ACGGT upstream-variant-2KB
rs2676563 -- 3,241,648(-) TTTCC(A/G)GTCTC downstream-variant-500B
rs2676571 -- 3,239,698(-) TTAAG(A/G)TATTA upstream-variant-2KB
rs57425169 -- 3,240,030(+) CCCCC(A/G)AATCT upstream-variant-2KB
rs58892697 -- 3,240,060(+) AAAAA(-/AAAAA)GAGTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR1D4 Gene

Variant ID Type Subtype PubMed ID
esv2660206 CNV Deletion 23128226
nsv7288 OTHER Inversion 18451855
dgv3n29 CNV Complex 16826518
nsv907553 CNV Loss 21882294
nsv469609 CNV Loss 16826518
nsv907554 CNV Loss 21882294
nsv526486 CNV Gain 19592680
nsv907555 CNV Loss 21882294
nsv907556 CNV Gain 21882294
nsv457637 CNV Loss 19166990
nsv907557 CNV Loss 21882294
nsv507831 CNV Insertion 20534489

Relevant External Links for OR1D4 Gene

HapMap Linkage Disequilibrium report
OR1D4

Disorders for OR1D4 Gene

No disorders were found for OR1D4 Gene.

No data available for UniProtKB/Swiss-Prot for OR1D4 Gene

Publications for OR1D4 Gene

  1. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. (PMID: 8004088) Ben-Arie N. … North M.A. (Hum. Mol. Genet. 1994) 2 3 4
  2. Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. (PMID: 10673334) Glusman G. … Lancet D. (Genomics 2000) 2 3 4
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3

Products for OR1D4 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate OR1D4
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for OR1D4
    • Block miRNA regulation of OR1D4 using miScript Target Protectors

    Sources for OR1D4 Gene

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