Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR1B1 Gene

Aliases for OR1B1 Gene

  • Olfactory Receptor, Family 1, Subfamily B, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor OR9-26 3 4
  • Olfactory Receptor 9-B 3 4
  • OR9-B 3 4
  • Olfactory Receptor 1B1 3
  • OR9-26 3

External Ids for OR1B1 Gene

Previous GeneCards Identifiers for OR1B1 Gene

  • GC09U990121
  • GC09M120767
  • GC09M122471
  • GC09M124430
  • GC09M125390

Summaries for OR1B1 Gene

Entrez Gene Summary for OR1B1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1B1 Gene

OR1B1 (Olfactory Receptor, Family 1, Subfamily B, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR1B1 Gene

  • Odorant receptor.

Gene Wiki entry for OR1B1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1B1 Gene

Genomics for OR1B1 Gene

Regulatory Elements for OR1B1 Gene

Genomic Location for OR1B1 Gene

122,628,579 bp from pter
122,629,535 bp from pter
957 bases
Minus strand

Genomic View for OR1B1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR1B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1B1 Gene

Proteins for OR1B1 Gene

  • Protein details for OR1B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 1B1
    Protein Accession:
    Secondary Accessions:
    • Q6IFN3

    Protein attributes for OR1B1 Gene

    318 amino acids
    Molecular mass:
    35293 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI16289.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=DAA04627.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR1B1 Gene

Proteomics data for OR1B1 Gene at MOPED

Post-translational modifications for OR1B1 Gene

  • Glycosylation at Asn7 and Asn23
  • Modification sites at PhosphoSitePlus

Other Protein References for OR1B1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1B1 Gene

Domains for OR1B1 Gene

Gene Families for OR1B1 Gene

Protein Domains for OR1B1 Gene

Suggested Antigen Peptide Sequences for OR1B1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1B1: view

Function for OR1B1 Gene

Molecular function for OR1B1 Gene

GENATLAS Biochemistry:
olfactory receptor, family1,subfamily B,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR1B1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR1B1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1B1 Gene

Localization for OR1B1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1B1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR1B1 Gene COMPARTMENTS Subcellular localization image for OR1B1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1B1: view

Pathways for OR1B1 Gene

genes like me logo Genes that share pathways with OR1B1: view

Pathways by source for OR1B1 Gene

Interacting Proteins for OR1B1 Gene

Gene Ontology (GO) - Biological Process for OR1B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1B1: view

Transcripts for OR1B1 Gene

mRNA/cDNA for OR1B1 Gene

(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR1B1 Gene

Olfactory receptor, family 1, subfamily B, member 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR1B1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR1B1 Gene

No ASD Table

Relevant External Links for OR1B1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR1B1 Gene

mRNA expression in normal human tissues for OR1B1 Gene

Protein differential expression in normal tissues for OR1B1 Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR1B1 Gene

SOURCE GeneReport for Unigene cluster for OR1B1 Gene Hs.553710

genes like me logo Genes that share expressions with OR1B1: view

Expression partners for OR1B1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR1B1 Gene

Orthologs for OR1B1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1B1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR1B1 35
  • 83.92 (n)
  • 80.63 (a)
OR1B1 36
  • 80 (a)
(Mus musculus)
Mammalia Olfr362 35
  • 84.6 (n)
  • 87.03 (a)
Olfr362 16
Olfr362 36
  • 87 (a)
(Rattus norvegicus)
Mammalia Olr425 35
  • 83.23 (n)
  • 85.13 (a)
(Monodelphis domestica)
Mammalia OR1B1 36
  • 71 (a)
Species with no ortholog for OR1B1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1B1 Gene

Gene Tree for OR1B1 (if available)
Gene Tree for OR1B1 (if available)

Paralogs for OR1B1 Gene

(445) SIMAP similar genes for OR1B1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR1B1: view

No data available for Paralogs for OR1B1 Gene

Variants for OR1B1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR1B1 Gene

A stop codon at position Arg-192 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans

Sequence variations from dbSNP and Humsavar for OR1B1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1024711 -- 122,628,175(+) TATAC(A/G)CAAAC downstream-variant-500B
rs1024712 -- 122,628,215(+) AATGT(C/G)ATGAT downstream-variant-500B
rs1329951 -- 122,629,638(-) ATCTT(C/T)AGTAA upstream-variant-2KB
rs1476858 - 122,628,747(+) TAGAC(A/C)CAAAT missense, reference
rs1476859 - 122,628,848(+) AATAG(C/T)GGCCC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR1B1 Gene

Variant ID Type Subtype PubMed ID
nsv893823 CNV Loss 21882294
nsv6705 CNV Insertion 18451855

Relevant External Links for OR1B1 Gene

HapMap Linkage Disequilibrium report

Disorders for OR1B1 Gene

Relevant External Links for OR1B1

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for OR1B1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR1B1 Gene

Publications for OR1B1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity. (PMID: 18328065) Koyano S. … Kawata S. (Hepatol. Res. 2008) 3 23
  4. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 4

Products for OR1B1 Gene

Sources for OR1B1 Gene

Back to Top