Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR14J1 Gene

Aliases for OR14J1 Gene

  • Olfactory Receptor Family 14 Subfamily J Member 1 2 3 5
  • Olfactory Receptor OR6-25 3 4
  • Olfactory Receptor 5U1 3 4
  • Hs6M1-28 3 4
  • OR5U1 3 4
  • Olfactory Receptor, Family 14, Subfamily J, Member 1 2
  • Olfactory Receptor, Family 5, Subfamily U, Member 1 2
  • Olfactory Receptor, Family 5, Subfamily U Member 1 3
  • Olfactory Receptor 14J1 3
  • BA150A6.4 3
  • OR6-25 3

External Ids for OR14J1 Gene

Previous HGNC Symbols for OR14J1 Gene

  • OR5U1

Previous GeneCards Identifiers for OR14J1 Gene

  • GC06P029384
  • GC06Po29204

Summaries for OR14J1 Gene

Entrez Gene Summary for OR14J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14J1 Gene

OR14J1 (Olfactory Receptor Family 14 Subfamily J Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR14A16.

UniProtKB/Swiss-Prot for OR14J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR14J1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14J1 Gene

Genomics for OR14J1 Gene

Regulatory Elements for OR14J1 Gene

Enhancers for OR14J1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F028586 0.7 ENCODE 16.2 -719.5 -719525 1.9 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 GPX6 GPX5 ZNF603P ZNF90P2 KRT18P1 OR2W1 OR2AD1P OR2P1P ENSG00000228364 OR2B3
GH06F030194 0.4 ENCODE 16.2 +888.6 888638 1.6 ZFP64 ARID4B DMAP1 YY1 SLC30A9 ZNF302 SP3 SP5 MXD4 ZHX2 HCG18 GTF2H4 PPP1R10 ETF1P1 DHX16 PAIP1P1 ZNRD1ASP HCG4P7 TRIM31 GNL1
GH06F030065 0.6 ENCODE 16.2 +760.1 760116 3.0 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 HCG4P3 PPP1R10 IFITM4P HLA-A TRIM26 PAIP1P1 RPL7P4 HCG4P7 HLA-P UBQLN1P1
GH06F029467 0.7 FANTOM5 11.1 +161.0 161010 0.3 OR10C1 ZFP57 MAS1L OR11A1 OR14J1 OR2W1 OR2J3 OR2B3 OR12D2 OR5V1
GH06F028814 0.9 FANTOM5 4.7 -492.3 -492313 0.1 ATF1 PKNOX1 CREB3L1 ZNF2 KLF7 REST ZNF518A KAT8 ZNF610 PBX2 ZNF311 ZKSCAN3 ZFP57 ZBED9 ZNF602P OR14J1 GPX6 OR2W1 OR2J3 OR2B3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR14J1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR14J1 Gene

Chromosome:
6
Start:
29,306,690 bp from pter
End:
29,307,655 bp from pter
Size:
966 bases
Orientation:
Plus strand

Genomic View for OR14J1 Gene

Genes around OR14J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR14J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR14J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR14J1 Gene

  • Protein details for OR14J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UGF5-O14J1_HUMAN
    Recommended name:
    Olfactory receptor 14J1
    Protein Accession:
    Q9UGF5
    Secondary Accessions:
    • A2BEC2
    • B0V078
    • Q5ST27

    Protein attributes for OR14J1 Gene

    Size:
    321 amino acids
    Molecular mass:
    35892 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14J1 Gene

Post-translational modifications for OR14J1 Gene

Other Protein References for OR14J1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR14J1 Gene

Domains & Families for OR14J1 Gene

Gene Families for OR14J1 Gene

Protein Domains for OR14J1 Gene

Suggested Antigen Peptide Sequences for OR14J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UGF5

UniProtKB/Swiss-Prot:

O14J1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR14J1: view

Function for OR14J1 Gene

Molecular function for OR14J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14J1: view
genes like me logo Genes that share phenotypes with OR14J1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR14J1 Gene

Localization for OR14J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR14J1 Gene COMPARTMENTS Subcellular localization image for OR14J1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR14J1: view

Pathways & Interactions for OR14J1 Gene

genes like me logo Genes that share pathways with OR14J1: view

Pathways by source for OR14J1 Gene

1 BioSystems pathway for OR14J1 Gene
1 KEGG pathway for OR14J1 Gene

Interacting Proteins for OR14J1 Gene

Gene Ontology (GO) - Biological Process for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14J1: view

No data available for SIGNOR curated interactions for OR14J1 Gene

Transcripts for OR14J1 Gene

mRNA/cDNA for OR14J1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR14J1 Gene

No ASD Table

Relevant External Links for OR14J1 Gene

GeneLoc Exon Structure for
OR14J1
ECgene alternative splicing isoforms for
OR14J1

Expression for OR14J1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR14J1 Gene

mRNA differential expression in normal tissues according to GTEx for OR14J1 Gene

This gene is overexpressed in Testis (x46.4).

NURSA nuclear receptor signaling pathways regulating expression of OR14J1 Gene:

OR14J1

SOURCE GeneReport for Unigene cluster for OR14J1 Gene:

Hs.632004
genes like me logo Genes that share expression patterns with OR14J1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR14J1 Gene

Orthologs for OR14J1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR14J1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC471935 34
  • 99.38 (n)
OR14J1 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC510530 34
  • 88.68 (n)
OR14J1 35
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100855565 34
  • 85.83 (n)
-- 35
  • 83 (a)
OneToMany
-- 35
  • 83 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Or14j1 55 Olfr125 34 16 35
  • 81.77 (n)
Or14j10 55 Olfr116
  • chr17:37,623,671-37,624,633
Or14j2 55 Olfr113
  • chr17:37,574,486-37,575,496
Or14j3 55 Olfr114
  • chr17:37,589,416-37,590,351
Or14j4 55 Olfr115
  • chr17:37,609,820-37,610,830
Or14j5 55 Olfr126
  • chr17:37,850,594-37,851,550
Or14j6 55 Olfr127
  • chr17:37,903,548-37,904,516
Or14j7 55 Olfr128
  • chr17:37,923,457-37,924,491
Or14j8 55 Olfr761
  • chr17:37,952,054-37,953,022
Or14j9 55 Olfr112
  • chr17:37,563,350-37,564,384
Or14q1-ps 55 Olfr756-ps1
  • chr17:37,285,147-37,286,045
rat
(Rattus norvegicus)
Mammalia Olr1693 34
  • 80.94 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 57 (a)
OneToMany
-- 35
  • 47 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 55 (a)
ManyToMany
chicken
(Gallus gallus)
Aves LOC101747306 34
  • 62.35 (n)
Species where no ortholog for OR14J1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14J1 Gene

ENSEMBL:
Gene Tree for OR14J1 (if available)
TreeFam:
Gene Tree for OR14J1 (if available)

Paralogs for OR14J1 Gene

Paralogs for OR14J1 Gene

(439) SIMAP similar genes for OR14J1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR14J1: view

Variants for OR14J1 Gene

Sequence variations from dbSNP and Humsavar for OR14J1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs111848393 -- 29,306,320(+) GCATC(A/G)TTGTA intron-variant, upstream-variant-2KB
rs112250320 -- 29,306,572(+) TTCAG(C/T)ACCTC intron-variant, upstream-variant-2KB
rs113587888 -- 29,306,563(+) TCATC(C/T)CATTT intron-variant, upstream-variant-2KB
rs115889365 -- 29,305,426(+) ATCCC(A/G)TTAAA intron-variant, upstream-variant-2KB
rs116013196 -- 29,304,766(+) TCTTA(C/T)GATTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR14J1 Gene

Variant ID Type Subtype PubMed ID
dgv10338n54 CNV gain 21841781
esv3608473 CNV gain 21293372
nsv1015796 CNV gain 25217958
nsv1020683 CNV gain 25217958
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1145096 CNV deletion 24896259
nsv830624 CNV loss 17160897

Variation tolerance for OR14J1 Gene

Residual Variation Intolerance Score: 63.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.71; 32.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR14J1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR14J1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR14J1 Gene

Disorders for OR14J1 Gene

Relevant External Links for OR14J1

Genetic Association Database (GAD)
OR14J1
Human Genome Epidemiology (HuGE) Navigator
OR14J1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR14J1

No disorders were found for OR14J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR14J1 Gene

Publications for OR14J1 Gene

  1. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 46 64
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR14J1 Gene

Sources for OR14J1 Gene

Content
Loading form....