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Aliases for OR14I1 Gene

Aliases for OR14I1 Gene

  • Olfactory Receptor, Family 14, Subfamily I, Member 1 2 3
  • Olfactory Receptor 5BU1 3 4
  • OR5BU1P 3 4
  • OR5BU1 3 4
  • Olfactory Receptor, Family 5, Subfamily BU, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 5, Subfamily BU, Member 1 2
  • Olfactory Receptor 14I1 3

External Ids for OR14I1 Gene

Previous Symbols for OR14I1 Gene

  • OR5BU1P
  • OR5BU1

Summaries for OR14I1 Gene

Entrez Gene Summary for OR14I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14I1 Gene

OR14I1 (Olfactory Receptor, Family 14, Subfamily I, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR14K1.

UniProtKB/Swiss-Prot for OR14I1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14I1 Gene

Genomics for OR14I1 Gene

Genomic Location for OR14I1 Gene

248,681,279 bp from pter
248,698,884 bp from pter
17,606 bases
Minus strand

Genomic View for OR14I1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR14I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR14I1 Gene

Regulatory Elements for OR14I1 Gene

Proteins for OR14I1 Gene

  • Protein details for OR14I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 14I1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for OR14I1 Gene

    311 amino acids
    Molecular mass:
    35175 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14I1 Gene

Proteomics data for OR14I1 Gene at MOPED

Post-translational modifications for OR14I1 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn3

Other Protein References for OR14I1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR14I1 Gene

Domains for OR14I1 Gene

Gene Families for OR14I1 Gene

  • OR14 :GPCR / Class A : Olfactory receptors

Protein Domains for OR14I1 Gene


  • Belongs to the G-protein coupled receptor 1 family.:
    • A6ND48
genes like me logo Genes that share domains with OR14I1: view

Function for OR14I1 Gene

Molecular function for OR14I1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14I1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR14I1 Gene

Localization for OR14I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR14I1 Gene COMPARTMENTS Subcellular localization image for OR14I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR14I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR14I1: view

Pathways for OR14I1 Gene

genes like me logo Genes that share pathways with OR14I1: view

Pathways by source for OR14I1 Gene

Interacting Proteins for OR14I1 Gene

Gene Ontology (GO) - Biological Process for OR14I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14I1: view

Transcripts for OR14I1 Gene

mRNA/cDNA for OR14I1 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR14I1 Gene

Olfactory receptor, family 14, subfamily I, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR14I1 Gene

No ASD Table

Relevant External Links for OR14I1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR14I1 Gene

mRNA expression in normal human tissues for OR14I1 Gene

mRNA differential expression in normal tissues according to GTEx for OR14I1 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (14.1), Brain - Anterior cingulate cortex (BA24) (11.3), and Brain - Cortex (10.1).

SOURCE GeneReport for Unigene cluster for OR14I1 Gene Hs.449973

genes like me logo Genes that share expressions with OR14I1: view

Orthologs for OR14I1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR14I1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC469772 36
  • 98.71 (n)
  • 96.78 (a)
OR14I1 37
  • 97 (a)
(Canis familiaris)
Mammalia LOC100686790 36
  • 83.01 (n)
  • 78.06 (a)
OR14I1 37
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 54 (a)
-- 37
  • 51 (a)
-- 37
  • 55 (a)
-- 37
  • 55 (a)
-- 37
  • 54 (a)
-- 37
  • 54 (a)
-- 37
  • 52 (a)
-- 37
  • 54 (a)
-- 37
  • 53 (a)
-- 37
  • 54 (a)
-- 37
  • 55 (a)
-- 37
  • 54 (a)
-- 37
  • 53 (a)
(Gallus gallus)
Aves OR14I1 37
  • 38 (a)
(Anolis carolinensis)
Reptilia -- 37
  • 45 (a)
-- 37
  • 47 (a)
-- 37
  • 42 (a)
-- 37
  • 43 (a)
-- 37
  • 46 (a)
-- 37
  • 43 (a)
-- 37
  • 42 (a)
-- 37
  • 46 (a)
-- 37
  • 47 (a)
-- 37
  • 47 (a)
-- 37
  • 49 (a)
-- 37
  • 46 (a)
Species with no ortholog for OR14I1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14I1 Gene

Gene Tree for OR14I1 (if available)
Gene Tree for OR14I1 (if available)

Paralogs for OR14I1 Gene

Paralogs for OR14I1 Gene

Selected SIMAP similar genes for OR14I1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR14I1: view

Variants for OR14I1 Gene

Sequence variations from dbSNP and Humsavar for OR14I1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1892439 -- 248,686,511(-) TTTAG(C/T)TTGAG intron-variant, upstream-variant-2KB
rs1892440 -- 248,700,475(-) ttagg(A/T)agtcc upstream-variant-2KB
rs1938128 -- 248,689,390(-) gcctc(C/T)GGTAG intron-variant
rs1938129 -- 248,689,313(-) TGGGA(A/C)TGCAG intron-variant
rs2000390 - 248,681,796(-) ATCCA(A/G)TGTGA missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR14I1 Gene

Variant ID Type Subtype PubMed ID
nsv515858 CNV Gain+Loss 19592680
esv2750832 CNV Gain 17911159
dgv20n17 CNV Loss 16327808
dgv206e1 CNV Complex 17122850
nsv428357 CNV Loss 18775914
esv2750835 CNV Gain 17911159
dgv208e1 CNV Complex 17122850
nsv483043 CNV Complex 15286789
nsv469750 CNV Loss 16826518
nsv873510 CNV Gain 21882294
nsv873518 CNV Gain 21882294
nsv5387 CNV Loss 18451855
esv32631 CNV Loss 17666407

Relevant External Links for OR14I1 Gene

HapMap Linkage Disequilibrium report

Disorders for OR14I1 Gene

Relevant External Links for OR14I1

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with OR14I1: view

No data available for UniProtKB/Swiss-Prot for OR14I1 Gene

Publications for OR14I1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for OR14I1 Gene

Sources for OR14I1 Gene

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