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Aliases for OR14C36 Gene

Aliases for OR14C36 Gene

  • Olfactory Receptor Family 14 Subfamily C Member 36 2 3 5
  • Olfactory Receptor, Family 5, Subfamily BF, Member 1 2 3
  • Olfactory Receptor OR1-59 3 4
  • Olfactory Receptor 5BF1 3 4
  • OR5BF1 3 4
  • Olfactory Receptor, Family 14, Subfamily C, Member 36 2
  • Olfactory Receptor 14C36 3

External Ids for OR14C36 Gene

Previous HGNC Symbols for OR14C36 Gene

  • OR5BF1

Previous GeneCards Identifiers for OR14C36 Gene

  • GC01P246579
  • GC01P248512

Summaries for OR14C36 Gene

Entrez Gene Summary for OR14C36 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14C36 Gene

OR14C36 (Olfactory Receptor Family 14 Subfamily C Member 36) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR14I1.

UniProtKB/Swiss-Prot for OR14C36 Gene

  • Odorant receptor.

Gene Wiki entry for OR14C36 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14C36 Gene

Genomics for OR14C36 Gene

Regulatory Elements for OR14C36 Gene

Enhancers for OR14C36 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G248431 0.6 dbSUPER 4.2 +83.7 83678 1.6 PKNOX1 BHLHE40 ZBTB11 BACH1 REST GABPA ZNF766 MLLT1 NR2C2 OR14C36 OR2T7 OR2T1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR14C36 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR14C36 Gene

Chromosome:
1
Start:
248,348,775 bp from pter
End:
248,349,713 bp from pter
Size:
939 bases
Orientation:
Plus strand

Genomic View for OR14C36 Gene

Genes around OR14C36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR14C36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR14C36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR14C36 Gene

Proteins for OR14C36 Gene

  • Protein details for OR14C36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHC7-O14CZ_HUMAN
    Recommended name:
    Olfactory receptor 14C36
    Protein Accession:
    Q8NHC7
    Secondary Accessions:
    • Q6IEZ6

    Protein attributes for OR14C36 Gene

    Size:
    312 amino acids
    Molecular mass:
    34815 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14C36 Gene

Post-translational modifications for OR14C36 Gene

  • Glycosylation at Asn3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR14C36 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR14C36 Gene

Domains & Families for OR14C36 Gene

Gene Families for OR14C36 Gene

Protein Domains for OR14C36 Gene

Suggested Antigen Peptide Sequences for OR14C36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NHC7

UniProtKB/Swiss-Prot:

O14CZ_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR14C36: view

Function for OR14C36 Gene

Molecular function for OR14C36 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14C36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14C36: view
genes like me logo Genes that share phenotypes with OR14C36: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR14C36 Gene

Localization for OR14C36 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14C36 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR14C36 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR14C36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR14C36: view

Pathways & Interactions for OR14C36 Gene

genes like me logo Genes that share pathways with OR14C36: view

Pathways by source for OR14C36 Gene

1 KEGG pathway for OR14C36 Gene

Interacting Proteins for OR14C36 Gene

Gene Ontology (GO) - Biological Process for OR14C36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14C36: view

No data available for SIGNOR curated interactions for OR14C36 Gene

Transcripts for OR14C36 Gene

mRNA/cDNA for OR14C36 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR14C36 Gene

No ASD Table

Relevant External Links for OR14C36 Gene

GeneLoc Exon Structure for
OR14C36
ECgene alternative splicing isoforms for
OR14C36

Expression for OR14C36 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR14C36 Gene

Protein differential expression in normal tissues from HIPED for OR14C36 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (62.2) and Platelet (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR14C36 Gene



Protein tissue co-expression partners for OR14C36 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR14C36 Gene:

OR14C36

SOURCE GeneReport for Unigene cluster for OR14C36 Gene:

Hs.553583
genes like me logo Genes that share expression patterns with OR14C36: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR14C36 Gene

Orthologs for OR14C36 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR14C36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469768 34
  • 98.61 (n)
OR14C36 35
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR14C36 35
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or14c44 55 Olfr301 34 16 35
  • 66.67 (n)
Or14c39 55 Olfr292 35
  • 60 (a)
OneToMany
Or14c41 55 Olfr295 35
  • 58 (a)
OneToMany
Or14c45 55 Olfr297 35
  • 57 (a)
OneToMany
Or14c40 55 Olfr293 35
  • 55 (a)
OneToMany
Or14c43 55 Olfr299 35
  • 55 (a)
OneToMany
Or14c46 55 Olfr310 35
  • 54 (a)
OneToMany
Or14c42-ps 55 Olfr296-ps1
  • chr7:86,561,734-86,562,660
Or14c47-ps 55 Olfr752-ps1
  • chr17:23,491,599-23,492,327
Or14n1-ps 55 Olfr300-ps1
  • chr7:86,442,968-86,443,918
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 63 (a)
OneToMany
-- 35
  • 62 (a)
OneToMany
-- 35
  • 62 (a)
OneToMany
-- 35
  • 62 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 61 (a)
OneToMany
-- 35
  • 60 (a)
OneToMany
-- 35
  • 60 (a)
OneToMany
-- 35
  • 60 (a)
OneToMany
-- 35
  • 60 (a)
OneToMany
-- 35
  • 60 (a)
OneToMany
-- 35
  • 59 (a)
OneToMany
-- 35
  • 59 (a)
OneToMany
-- 35
  • 59 (a)
OneToMany
-- 35
  • 59 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
-- 35
  • 58 (a)
OneToMany
cow
(Bos Taurus)
Mammalia OR14C36 35
  • 60 (a)
OneToOne
Species where no ortholog for OR14C36 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14C36 Gene

ENSEMBL:
Gene Tree for OR14C36 (if available)
TreeFam:
Gene Tree for OR14C36 (if available)

Paralogs for OR14C36 Gene

Paralogs for OR14C36 Gene

(442) SIMAP similar genes for OR14C36 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR14C36: view

Variants for OR14C36 Gene

Sequence variations from dbSNP and Humsavar for OR14C36 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000121666 -- 248,348,663(+) AGATT(A/G)CAACT upstream-variant-2KB
rs1001744973 -- 248,349,726(+) GAGAG(A/C/G)CTCAC downstream-variant-500B
rs1005517285 -- 248,349,472(+) CAGAA(C/G)AAAGG reference, missense
rs1005852782 -- 248,347,987(+) TGTGC(C/T)CTCAA upstream-variant-2KB
rs1007659917 -- 248,347,940(+) CTTAA(A/G)TTGAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR14C36 Gene

Variant ID Type Subtype PubMed ID
dgv17e55 CNV loss 17911159
dgv20n17 CNV loss 16327808
dgv606n100 CNV gain 25217958
dgv607n100 CNV loss 25217958
dgv608n100 CNV gain 25217958
dgv613n100 CNV loss 25217958
dgv906n54 CNV gain 21841781
esv2750832 CNV gain 17911159
esv2759015 CNV gain+loss 17122850
esv3589547 CNV gain 21293372
esv3891415 CNV gain 25118596
nsv1001474 CNV gain 25217958
nsv1004790 CNV gain 25217958
nsv1013273 CNV gain 25217958
nsv428357 CNV loss 18775914
nsv515858 CNV gain+loss 19592680
nsv5332 CNV deletion 18451855
nsv549603 CNV loss 21841781
nsv549626 CNV loss 21841781
nsv549630 CNV loss 21841781
nsv9114 CNV gain 18304495

Variation tolerance for OR14C36 Gene

Residual Variation Intolerance Score: 75.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 15.80; 97.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR14C36 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR14C36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR14C36 Gene

Disorders for OR14C36 Gene

Relevant External Links for OR14C36

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR14C36

No disorders were found for OR14C36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR14C36 Gene

Publications for OR14C36 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64

Products for OR14C36 Gene

Sources for OR14C36 Gene

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