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Aliases for OR14A2 Gene

Aliases for OR14A2 Gene

  • Olfactory Receptor, Family 14, Subfamily A, Member 2 2 3
  • Olfactory Receptor, Family 5, Subfamily AX, Member 1 Pseudogene 2 3
  • OR5AX1P 3 4
  • OR5AX1 3 4
  • Olfactory Receptor, Family 5, Subfamily AX, Member 1 2
  • Olfactory Receptor OR1-31 4
  • Olfactory Receptor 5AX1 4

External Ids for OR14A2 Gene

Previous Symbols for OR14A2 Gene

  • OR5AX1P
  • OR5AX1

Summaries for OR14A2 Gene

Entrez Gene Summary for OR14A2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14A2 Gene

OR14A2 (Olfactory Receptor, Family 14, Subfamily A, Member 2) is a Pseudogene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR14K1.

UniProtKB/Swiss-Prot for OR14A2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14A2 Gene

Genomics for OR14A2 Gene

Genomic Location for OR14A2 Gene

Start:
247,722,899 bp from pter
End:
247,724,243 bp from pter
Size:
1,345 bases
Orientation:
Minus strand

Genomic View for OR14A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR14A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR14A2 Gene

No data available for Regulatory Elements for OR14A2 Gene

Proteins for OR14A2 Gene

  • Protein details for OR14A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96R54-O14A2_HUMAN
    Recommended name:
    Olfactory receptor 14A2
    Protein Accession:
    Q96R54
    Secondary Accessions:

    Protein attributes for OR14A2 Gene

    Size:
    314 amino acids
    Molecular mass:
    34780 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14A2 Gene

Proteomics data for OR14A2 Gene at MOPED

Post-translational modifications for OR14A2 Gene

Other Protein References for OR14A2 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for OR14A2 Gene

Domains for OR14A2 Gene

Gene Families for OR14A2 Gene

HGNC:
  • OR14 :GPCR / Class A : Olfactory receptors

Protein Domains for OR14A2 Gene

Suggested Antigen Peptide Sequences for OR14A2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96R54

UniProtKB/Swiss-Prot:

O14A2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q96R54
genes like me logo Genes that share domains with OR14A2: view

Function for OR14A2 Gene

Molecular function for OR14A2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14A2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR14A2 Gene

Localization for OR14A2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14A2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR14A2 Gene COMPARTMENTS Subcellular localization image for OR14A2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR14A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR14A2: view

Pathways for OR14A2 Gene

genes like me logo Genes that share pathways with OR14A2: view

Pathways by source for OR14A2 Gene

Interacting Proteins for OR14A2 Gene

Gene Ontology (GO) - Biological Process for OR14A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14A2: view

Transcripts for OR14A2 Gene

mRNA/cDNA for OR14A2 Gene

(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR14A2 Gene

No ASD Table

Relevant External Links for OR14A2 Gene

GeneLoc Exon Structure for
OR14A2
ECgene alternative splicing isoforms for
OR14A2

Expression for OR14A2 Gene

mRNA expression in normal human tissues for OR14A2 Gene

mRNA differential expression in normal tissues according to GTEx for OR14A2 Gene

This gene is overexpressed in Testis (52.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR14A2 Gene

genes like me logo Genes that share expressions with OR14A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR14A2 Gene

Orthologs for OR14A2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR14A2 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Olfr294 36
  • 64 (a)
OneToMany
Olfr298 36
  • 66 (a)
OneToMany
Olfr304 36
  • 69 (a)
OneToMany
Olfr305 36
  • 71 (a)
OneToMany
Olfr307 36
  • 72 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 63 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
-- 36
  • 61 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 61 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 52 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
Species with no ortholog for OR14A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14A2 Gene

ENSEMBL:
Gene Tree for OR14A2 (if available)
TreeFam:
Gene Tree for OR14A2 (if available)

Paralogs for OR14A2 Gene

Paralogs for OR14A2 Gene

Selected SIMAP similar genes for OR14A2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR14A2 Gene

genes like me logo Genes that share paralogs with OR14A2: view

Variants for OR14A2 Gene

Relevant External Links for OR14A2 Gene

HapMap Linkage Disequilibrium report
OR14A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR14A2 Gene

Disorders for OR14A2 Gene

No disorders were found for OR14A2 Gene.

No data available for UniProtKB/Swiss-Prot for OR14A2 Gene

Publications for OR14A2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 4

Products for OR14A2 Gene

Sources for OR14A2 Gene

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