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Aliases for OR14A16 Gene

Aliases for OR14A16 Gene

  • Olfactory Receptor, Family 14, Subfamily A, Member 16 2 3
  • Olfactory Receptor, Family 5, Subfamily AT, Member 1 2 3
  • Olfactory Receptor OR1-45 3 4
  • Olfactory Receptor 5AT1 3 4
  • OR5AT1 3 4
  • Olfactory Receptor 14A16 3

External Ids for OR14A16 Gene

Previous Symbols for OR14A16 Gene

  • OR5AT1

Summaries for OR14A16 Gene

Entrez Gene Summary for OR14A16 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14A16 Gene

OR14A16 (Olfactory Receptor, Family 14, Subfamily A, Member 16) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR14K1.

UniProtKB/Swiss-Prot for OR14A16 Gene

  • Odorant receptor.

Gene Wiki entry for OR14A16 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14A16 Gene

Genomics for OR14A16 Gene

Genomic Location for OR14A16 Gene

Start:
247,814,800 bp from pter
End:
247,845,181 bp from pter
Size:
30,382 bases
Orientation:
Minus strand

Genomic View for OR14A16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR14A16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR14A16 Gene

Regulatory Elements for OR14A16 Gene

Proteins for OR14A16 Gene

  • Protein details for OR14A16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHC5-O14AG_HUMAN
    Recommended name:
    Olfactory receptor 14A16
    Protein Accession:
    Q8NHC5
    Secondary Accessions:
    • Q6IF96

    Protein attributes for OR14A16 Gene

    Size:
    309 amino acids
    Molecular mass:
    34307 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04764.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR14A16 Gene

Proteomics data for OR14A16 Gene at MOPED

Post-translational modifications for OR14A16 Gene

Other Protein References for OR14A16 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR14A16 Gene

Domains for OR14A16 Gene

Gene Families for OR14A16 Gene

HGNC:
  • OR14 :GPCR / Class A : Olfactory receptors

Protein Domains for OR14A16 Gene

UniProtKB/Swiss-Prot:

O14AG_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NHC5
genes like me logo Genes that share domains with OR14A16: view

Function for OR14A16 Gene

Molecular function for OR14A16 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14A16: view

Phenotypes for OR14A16 Gene

GenomeRNAi human phenotypes for OR14A16:
genes like me logo Genes that share phenotypes with OR14A16: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR14A16 Gene

Localization for OR14A16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14A16 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR14A16 Gene COMPARTMENTS Subcellular localization image for OR14A16 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR14A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR14A16: view

Pathways for OR14A16 Gene

genes like me logo Genes that share pathways with OR14A16: view

Pathways by source for OR14A16 Gene

1 KEGG pathway for OR14A16 Gene

Interacting Proteins for OR14A16 Gene

Gene Ontology (GO) - Biological Process for OR14A16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14A16: view

Transcripts for OR14A16 Gene

mRNA/cDNA for OR14A16 Gene

(4) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR14A16 Gene

No ASD Table

Relevant External Links for OR14A16 Gene

GeneLoc Exon Structure for
OR14A16
ECgene alternative splicing isoforms for
OR14A16

Expression for OR14A16 Gene

mRNA expression in normal human tissues for OR14A16 Gene

mRNA differential expression in normal tissues according to GTEx for OR14A16 Gene

This gene is overexpressed in Testis (39.8) and Thyroid (13.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR14A16 Gene

SOURCE GeneReport for Unigene cluster for OR14A16 Gene Hs.626620

genes like me logo Genes that share expressions with OR14A16: view

Orthologs for OR14A16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR14A16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC740188 36
  • 98.27 (n)
  • 96.12 (a)
OR14A16 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC101904415 36
  • 60.84 (n)
  • 52.15 (a)
OR14A16 37
  • 52 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr761 37
  • 47 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 53 (a)
OneToMany
-- 37
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 53 (a)
OneToMany
-- 37
  • 51 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
-- 37
  • 52 (a)
OneToMany
-- 37
  • 52 (a)
OneToMany
-- 37
  • 53 (a)
OneToMany
-- 37
  • 50 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
-- 37
  • 57 (a)
OneToMany
-- 37
  • 53 (a)
OneToMany
-- 37
  • 57 (a)
OneToMany
-- 37
  • 50 (a)
OneToMany
-- 37
  • 53 (a)
OneToMany
-- 37
  • 52 (a)
OneToMany
-- 37
  • 56 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
-- 37
  • 54 (a)
OneToMany
-- 37
  • 57 (a)
OneToMany
-- 37
  • 56 (a)
OneToMany
-- 37
  • 56 (a)
OneToMany
-- 37
  • 48 (a)
OneToMany
-- 37
  • 56 (a)
OneToMany
-- 37
  • 57 (a)
OneToMany
-- 37
  • 53 (a)
OneToMany
-- 37
  • 52 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
-- 37
  • 55 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1653 36
  • 59.69 (n)
  • 51.63 (a)
Species with no ortholog for OR14A16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14A16 Gene

ENSEMBL:
Gene Tree for OR14A16 (if available)
TreeFam:
Gene Tree for OR14A16 (if available)

Paralogs for OR14A16 Gene

Paralogs for OR14A16 Gene

Selected SIMAP similar genes for OR14A16 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR14A16 Gene

genes like me logo Genes that share paralogs with OR14A16: view

Variants for OR14A16 Gene

Sequence variations from dbSNP and Humsavar for OR14A16 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs980398 -- 247,822,505(+) GCCTT(A/G)GACTT intron-variant
rs1007592 -- 247,823,472(+) ctcca(G/T)cctgg intron-variant
rs1007593 -- 247,823,939(+) AATAC(C/T)GTTCC intron-variant
rs1339846 -- 247,820,386(-) aaaaa(A/T)cataa intron-variant, upstream-variant-2KB
rs1389227 -- 247,834,475(-) ATATA(A/C)CTTAA upstream-variant-2KB, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR14A16 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv873442 CNV Gain 21882294
dgv205e1 CNV Complex 17122850

Relevant External Links for OR14A16 Gene

HapMap Linkage Disequilibrium report
OR14A16

Disorders for OR14A16 Gene

No disorders were found for OR14A16 Gene.

No data available for UniProtKB/Swiss-Prot for OR14A16 Gene

Publications for OR14A16 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR14A16 Gene

Sources for OR14A16 Gene

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