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Aliases for OR13G1 Gene

Aliases for OR13G1 Gene

  • Olfactory Receptor Family 13 Subfamily G Member 1 2 3 5
  • Olfactory Receptor, Family 13, Subfamily G, Member 1 2 3
  • Olfactory Receptor OR1-37 3 4
  • OR1-37 3

External Ids for OR13G1 Gene

Previous GeneCards Identifiers for OR13G1 Gene

  • GC01U990418
  • GC01M244161
  • GC01M245902
  • GC01M247835

Summaries for OR13G1 Gene

Entrez Gene Summary for OR13G1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13G1 Gene

OR13G1 (Olfactory Receptor Family 13 Subfamily G Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR13A1.

UniProtKB/Swiss-Prot for OR13G1 Gene

  • Odorant receptor.

Gene Wiki entry for OR13G1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13G1 Gene

Genomics for OR13G1 Gene

Regulatory Elements for OR13G1 Gene

Genomic Location for OR13G1 Gene

Chromosome:
1
Start:
247,672,118 bp from pter
End:
247,673,041 bp from pter
Size:
924 bases
Orientation:
Minus strand

Genomic View for OR13G1 Gene

Genes around OR13G1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13G1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13G1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13G1 Gene

Proteins for OR13G1 Gene

  • Protein details for OR13G1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGZ3-O13G1_HUMAN
    Recommended name:
    Olfactory receptor 13G1
    Protein Accession:
    Q8NGZ3
    Secondary Accessions:
    • B2RN80
    • Q5T2T2
    • Q6IF86

    Protein attributes for OR13G1 Gene

    Size:
    307 amino acids
    Molecular mass:
    34672 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13G1 Gene

Proteomics data for OR13G1 Gene at MOPED

Post-translational modifications for OR13G1 Gene

  • Glycosylation at Asn 2
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13G1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13G1 Gene

Domains & Families for OR13G1 Gene

Gene Families for OR13G1 Gene

Protein Domains for OR13G1 Gene

Suggested Antigen Peptide Sequences for OR13G1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGZ3

UniProtKB/Swiss-Prot:

O13G1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13G1: view

Function for OR13G1 Gene

Molecular function for OR13G1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with OR13G1: view
genes like me logo Genes that share phenotypes with OR13G1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13G1 Gene

Localization for OR13G1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13G1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR13G1 Gene COMPARTMENTS Subcellular localization image for OR13G1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR13G1: view

Pathways & Interactions for OR13G1 Gene

genes like me logo Genes that share pathways with OR13G1: view

Pathways by source for OR13G1 Gene

Interacting Proteins for OR13G1 Gene

Gene Ontology (GO) - Biological Process for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13G1: view

No data available for SIGNOR curated interactions for OR13G1 Gene

Drugs & Compounds for OR13G1 Gene

No Compound Related Data Available

Transcripts for OR13G1 Gene

mRNA/cDNA for OR13G1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR13G1 Gene

No ASD Table

Relevant External Links for OR13G1 Gene

GeneLoc Exon Structure for
OR13G1
ECgene alternative splicing isoforms for
OR13G1

Expression for OR13G1 Gene

mRNA expression in normal human tissues for OR13G1 Gene

mRNA differential expression in normal tissues according to GTEx for OR13G1 Gene

This gene is overexpressed in Testis (x27.7).

SOURCE GeneReport for Unigene cluster for OR13G1 Gene Hs.553834

genes like me logo Genes that share expression patterns with OR13G1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR13G1 Gene

Orthologs for OR13G1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR13G1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia OR13G1 35
  • 85.45 (n)
  • 82.41 (a)
OR13G1 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr309 35
  • 84.42 (n)
  • 84.97 (a)
Olfr309 16
Olfr309 36
  • 84 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC469749 35
  • 99.24 (n)
  • 98.37 (a)
OR13G1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr12 35
  • 83.12 (n)
  • 85.95 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 52 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia OR13G1 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 46 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
Species with no ortholog for OR13G1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13G1 Gene

ENSEMBL:
Gene Tree for OR13G1 (if available)
TreeFam:
Gene Tree for OR13G1 (if available)

Paralogs for OR13G1 Gene

Paralogs for OR13G1 Gene

(451) SIMAP similar genes for OR13G1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR13G1: view

Variants for OR13G1 Gene

Sequence variations from dbSNP and Humsavar for OR13G1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1151640 - 247,672,648(-) GTACT(A/G)TTATG reference, missense
rs28711149 - 247,672,905(+) AGATT(A/T)TGGCA reference, missense
rs28556931 - 247,672,606(+) AGCCA(A/T)GACCA reference, missense
rs28446289 - 247,672,372(+) GATAC(A/G)GAGAA reference, missense
rs1151639 -- 247,673,816(-) GGCCA(A/G)TCTAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR13G1 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv5310 CNV Loss 18451855

Variation tolerance for OR13G1 Gene

Residual Variation Intolerance Score: 77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 15.79; 97.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR13G1 Gene

HapMap Linkage Disequilibrium report
OR13G1
Human Gene Mutation Database (HGMD)
OR13G1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13G1 Gene

Disorders for OR13G1 Gene

Relevant External Links for OR13G1

Genetic Association Database (GAD)
OR13G1
Human Genome Epidemiology (HuGE) Navigator
OR13G1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR13G1

No disorders were found for OR13G1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13G1 Gene

Publications for OR13G1 Gene

  1. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. (PMID: 18599554) van der Net J.B. … Sijbrands E.J. (Eur. Heart J. 2008) 3 23 48 67
  2. Variations of specific non-candidate genes and risk of myocardial infarction: a replication study. (PMID: 19709766) Koch W. … Kastrati A. (Int. J. Cardiol. 2011) 3
  3. Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke M.M. … Psaty B.M. (Stroke 2009) 3
  4. Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. (PMID: 19056482) Yoshida T. … Yamada Y. (Genomics 2009) 3
  5. Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia. (PMID: 19166692) van der Net J.B. … Steyerberg E.W. (Am. J. Cardiol. 2009) 3

Products for OR13G1 Gene

Sources for OR13G1 Gene

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