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Aliases for OR13D1 Gene

Aliases for OR13D1 Gene

  • Olfactory Receptor Family 13 Subfamily D Member 1 2 3 5
  • Olfactory Receptor OR9-15 3 4
  • Olfactory Receptor, Family 13, Subfamily D, Member 1 2
  • Olfactory Receptor 13D1 3
  • OR9-15 3

External Ids for OR13D1 Gene

Previous GeneCards Identifiers for OR13D1 Gene

  • GC09U990158
  • GC09P102837
  • GC09P104536
  • GC09P106496
  • GC09P107456

Summaries for OR13D1 Gene

Entrez Gene Summary for OR13D1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13D1 Gene

OR13D1 (Olfactory Receptor Family 13 Subfamily D Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2K2.

UniProtKB/Swiss-Prot for OR13D1 Gene

  • Odorant receptor.

Gene Wiki entry for OR13D1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13D1 Gene

Genomics for OR13D1 Gene

Regulatory Elements for OR13D1 Gene

Enhancers for OR13D1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F104740 0.5 Ensembl 10.5 +46.4 46379 0.4 ZNF274 JUN CEBPB KAT2B OR13D1 NIPSNAP3A OR13D3P
GH09F104586 0.4 ENCODE 9.9 -107.7 -107728 0.2 POLR2A MNT NIPSNAP3A OR13C3 OR13D1 OR13D2P OR13C8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR13D1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR13D1 Gene

Chromosome:
9
Start:
104,694,422 bp from pter
End:
104,695,462 bp from pter
Size:
1,041 bases
Orientation:
Plus strand

Genomic View for OR13D1 Gene

Genes around OR13D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13D1 Gene

Proteins for OR13D1 Gene

  • Protein details for OR13D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGV5-O13D1_HUMAN
    Recommended name:
    Olfactory receptor 13D1
    Protein Accession:
    Q8NGV5
    Secondary Accessions:
    • B9EIS1
    • Q6IFL1

    Protein attributes for OR13D1 Gene

    Size:
    346 amino acids
    Molecular mass:
    39125 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13D1 Gene

Post-translational modifications for OR13D1 Gene

  • Glycosylation at Asn 37 and Asn 300
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13D1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13D1 Gene

Domains & Families for OR13D1 Gene

Gene Families for OR13D1 Gene

Protein Domains for OR13D1 Gene

Suggested Antigen Peptide Sequences for OR13D1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGV5

UniProtKB/Swiss-Prot:

O13D1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13D1: view

Function for OR13D1 Gene

Molecular function for OR13D1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13D1: view
genes like me logo Genes that share phenotypes with OR13D1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13D1 Gene

Localization for OR13D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13D1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13D1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13D1: view

Pathways & Interactions for OR13D1 Gene

genes like me logo Genes that share pathways with OR13D1: view

Pathways by source for OR13D1 Gene

Interacting Proteins for OR13D1 Gene

Gene Ontology (GO) - Biological Process for OR13D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA,IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13D1: view

No data available for SIGNOR curated interactions for OR13D1 Gene

Transcripts for OR13D1 Gene

mRNA/cDNA for OR13D1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13D1 Gene

No ASD Table

Relevant External Links for OR13D1 Gene

GeneLoc Exon Structure for
OR13D1
ECgene alternative splicing isoforms for
OR13D1

Expression for OR13D1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR13D1 Gene

mRNA differential expression in normal tissues according to GTEx for OR13D1 Gene

This gene is overexpressed in Testis (x17.6).

NURSA nuclear receptor signaling pathways regulating expression of OR13D1 Gene:

OR13D1

SOURCE GeneReport for Unigene cluster for OR13D1 Gene:

Hs.553683
genes like me logo Genes that share expression patterns with OR13D1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR13D1 Gene

Orthologs for OR13D1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC464628 34
  • 99.03 (n)
OR13D1 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 35
  • 88 (a)
OneToMany
-- 35
  • 87 (a)
OneToMany
LOC610556 34
  • 86.22 (n)
-- 35
  • 84 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Or13d1 55 Olfr270 34 16 35
  • 84.3 (n)
rat
(Rattus norvegicus)
Mammalia Olr853 34
  • 84.19 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 78 (a)
OneToMany
-- 35
  • 78 (a)
OneToMany
-- 35
  • 75 (a)
OneToMany
-- 35
  • 73 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
-- 35
  • 70 (a)
OneToMany
-- 35
  • 69 (a)
OneToMany
-- 35
  • 68 (a)
OneToMany
-- 35
  • 65 (a)
OneToMany
-- 35
  • 65 (a)
OneToMany
OPOR64 35
  • 65 (a)
OneToMany
-- 35
  • 63 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia OR13D1 35
  • 71 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR13D1 35
  • 62 (a)
OneToOne
Species where no ortholog for OR13D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13D1 Gene

ENSEMBL:
Gene Tree for OR13D1 (if available)
TreeFam:
Gene Tree for OR13D1 (if available)

Paralogs for OR13D1 Gene

(445) SIMAP similar genes for OR13D1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR13D1 Gene

genes like me logo Genes that share paralogs with OR13D1: view

Variants for OR13D1 Gene

Sequence variations from dbSNP and Humsavar for OR13D1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10640172 -- 104,693,931(+) TGCAT(-/AC/ACACAC)ACACA intron-variant, upstream-variant-2KB
rs10761073 -- 104,695,251(+) GCACT(C/T)GATTG intron-variant, reference, missense
rs10820708 -- 104,694,224(+) TATTT(C/G)ACACT intron-variant, upstream-variant-2KB
rs10820709 -- 104,694,994(+) TTGCA(A/C)ACAGT intron-variant, reference, missense
rs10991358 -- 104,693,077(+) gtaat(C/T)tcagc intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR13D1 Gene

Variant ID Type Subtype PubMed ID
esv3891706 CNV gain 25118596
esv3891705 CNV loss 25118596
esv3573336 CNV loss 25503493
dgv2175e212 CNV loss 25503493

Variation tolerance for OR13D1 Gene

Residual Variation Intolerance Score: 91.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.31; 81.44% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR13D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR13D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13D1 Gene

Disorders for OR13D1 Gene

Relevant External Links for OR13D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR13D1

No disorders were found for OR13D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13D1 Gene

Publications for OR13D1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR13D1 Gene

Sources for OR13D1 Gene

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