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Aliases for OR13C9 Gene

Aliases for OR13C9 Gene

  • Olfactory Receptor Family 13 Subfamily C Member 9 2 3 5
  • Olfactory Receptor OR9-13 3 4
  • Olfactory Receptor, Family 13, Subfamily C, Member 9 2
  • Olfactory Receptor 13C9 3
  • OR9-13 3
  • OR37L 3

External Ids for OR13C9 Gene

Previous GeneCards Identifiers for OR13C9 Gene

  • GC09U990180
  • GC09M102760
  • GC09M104459
  • GC09M106419
  • GC09M107379

Summaries for OR13C9 Gene

Entrez Gene Summary for OR13C9 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C9 Gene

OR13C9 (Olfactory Receptor Family 13 Subfamily C Member 9) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR13C2.

UniProtKB/Swiss-Prot for OR13C9 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C9 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C9 Gene

Genomics for OR13C9 Gene

Regulatory Elements for OR13C9 Gene


Genomic Location for OR13C9 Gene

Chromosome:
9
Start:
104,617,248 bp from pter
End:
104,618,204 bp from pter
Size:
957 bases
Orientation:
Minus strand

Genomic View for OR13C9 Gene

Genes around OR13C9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13C9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13C9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C9 Gene

Proteins for OR13C9 Gene

  • Protein details for OR13C9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGT0-O13C9_HUMAN
    Recommended name:
    Olfactory receptor 13C9
    Protein Accession:
    Q8NGT0
    Secondary Accessions:
    • Q6IFL2

    Protein attributes for OR13C9 Gene

    Size:
    318 amino acids
    Molecular mass:
    35854 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13C9 Gene

Post-translational modifications for OR13C9 Gene

Other Protein References for OR13C9 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13C9 Gene

Domains & Families for OR13C9 Gene

Gene Families for OR13C9 Gene

Protein Domains for OR13C9 Gene

Suggested Antigen Peptide Sequences for OR13C9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGT0

UniProtKB/Swiss-Prot:

O13C9_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C9: view

Function for OR13C9 Gene

Molecular function for OR13C9 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C9: view
genes like me logo Genes that share phenotypes with OR13C9: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13C9 Gene

Localization for OR13C9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C9 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13C9 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C9: view

Pathways & Interactions for OR13C9 Gene

genes like me logo Genes that share pathways with OR13C9: view

Pathways by source for OR13C9 Gene

Interacting Proteins for OR13C9 Gene

Gene Ontology (GO) - Biological Process for OR13C9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA,IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13C9: view

No data available for SIGNOR curated interactions for OR13C9 Gene

Drugs & Compounds for OR13C9 Gene

No Compound Related Data Available

Transcripts for OR13C9 Gene

mRNA/cDNA for OR13C9 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C9 Gene

No ASD Table

Relevant External Links for OR13C9 Gene

GeneLoc Exon Structure for
OR13C9
ECgene alternative splicing isoforms for
OR13C9

Expression for OR13C9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR13C9 Gene

mRNA differential expression in normal tissues according to GTEx for OR13C9 Gene

This gene is overexpressed in Pituitary (x15.2), Brain - Cortex (x5.9), Cervix - Endocervix (x5.6), and Brain - Spinal cord (cervical c-1) (x4.5).

NURSA nuclear receptor signaling pathways regulating expression of OR13C9 Gene:

OR13C9

SOURCE GeneReport for Unigene cluster for OR13C9 Gene:

Hs.553682
genes like me logo Genes that share expression patterns with OR13C9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR13C9 Gene

Orthologs for OR13C9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C9 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 35
  • 93 (a)
ManyToMany
-- 35
  • 89 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 86 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 84 (a)
ManyToMany
-- 35
  • 84 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr159 35
  • 68 (a)
ManyToMany
Or13c9 55 Olfr271
  • chr4:52,935,433-52,936,284
Species where no ortholog for OR13C9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C9 Gene

ENSEMBL:
Gene Tree for OR13C9 (if available)
TreeFam:
Gene Tree for OR13C9 (if available)

Paralogs for OR13C9 Gene

(451) SIMAP similar genes for OR13C9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR13C9: view

Variants for OR13C9 Gene

Sequence variations from dbSNP and Humsavar for OR13C9 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1001357547 -- 104,619,098(+) ACCTG(C/T)ACATC upstream-variant-2KB
rs1002411743 -- 104,619,860(+) TTCCT(C/T)GTTGA upstream-variant-2KB
rs1003418111 -- 104,618,418(+) AAGCT(C/T)ATGAT upstream-variant-2KB
rs1004794282 -- 104,620,096(+) AAATA(G/T)CCACT upstream-variant-2KB
rs1006925872 -- 104,619,019(+) CATAA(C/G)CAGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR13C9 Gene

Variant ID Type Subtype PubMed ID
dgv1498e214 CNV loss 21293372
esv2759707 CNV gain+loss 17122850
esv2761260 CNV gain+loss 21179565
esv3621337 CNV gain 21293372
esv3891705 CNV loss 25118596
esv3891706 CNV gain 25118596
nsv471313 CNV loss 18288195
nsv831677 CNV gain 17160897
nsv968741 CNV duplication 23825009
nsv969772 CNV duplication 23825009

Variation tolerance for OR13C9 Gene

Residual Variation Intolerance Score: 95.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 20.79; 99.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR13C9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR13C9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C9 Gene

Disorders for OR13C9 Gene

Relevant External Links for OR13C9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR13C9

No disorders were found for OR13C9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13C9 Gene

Publications for OR13C9 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  3. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R. … Strotmann J. (Genomics 2003) 3 64

Products for OR13C9 Gene

Sources for OR13C9 Gene

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