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Aliases for OR13C8 Gene

Aliases for OR13C8 Gene

  • Olfactory Receptor Family 13 Subfamily C Member 8 2 3 5
  • Olfactory Receptor, Family 13, Subfamily C, Member 8 2
  • Olfactory Receptor OR9-10 Pseudogene 3
  • Olfactory Receptor 13C8 3
  • OR9-10 3
  • OR37H 3

External Ids for OR13C8 Gene

Previous GeneCards Identifiers for OR13C8 Gene

  • GC09U990181
  • GC09P102712
  • GC09P104412
  • GC09P106371
  • GC09P107331

Summaries for OR13C8 Gene

Entrez Gene Summary for OR13C8 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C8 Gene

OR13C8 (Olfactory Receptor Family 13 Subfamily C Member 8) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2S2.

UniProtKB/Swiss-Prot for OR13C8 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C8 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C8 Gene

Genomics for OR13C8 Gene

Regulatory Elements for OR13C8 Gene

Enhancers for OR13C8 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F104971 0.3 FANTOM5 2.4 +402.8 402764 0.0 OR13C3 SLC44A1 OR13C8 GC09P104984 ABCA1
GH09F104586 0.4 ENCODE 0.3 +17.5 17527 0.2 POLR2A MNT NIPSNAP3A OR13C3 OR13D1 OR13D2P OR13C8
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR13C8 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR13C8 Gene

104,569,168 bp from pter
104,570,130 bp from pter
963 bases
Plus strand

Genomic View for OR13C8 Gene

Genes around OR13C8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13C8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13C8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C8 Gene

Proteins for OR13C8 Gene

  • Protein details for OR13C8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 13C8
    Protein Accession:
    Secondary Accessions:
    • Q5VVG0
    • Q96R44

    Protein attributes for OR13C8 Gene

    320 amino acids
    Molecular mass:
    35294 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13C8 Gene

Post-translational modifications for OR13C8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR13C8 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13C8 Gene

Domains & Families for OR13C8 Gene

Gene Families for OR13C8 Gene

Protein Domains for OR13C8 Gene

Suggested Antigen Peptide Sequences for OR13C8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C8: view

Function for OR13C8 Gene

Molecular function for OR13C8 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13C8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C8: view

Phenotypes for OR13C8 Gene

GenomeRNAi human phenotypes for OR13C8:
genes like me logo Genes that share phenotypes with OR13C8: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13C8 Gene

Localization for OR13C8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C8 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR13C8 Gene COMPARTMENTS Subcellular localization image for OR13C8 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13C8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C8: view

Pathways & Interactions for OR13C8 Gene

genes like me logo Genes that share pathways with OR13C8: view

Pathways by source for OR13C8 Gene

Gene Ontology (GO) - Biological Process for OR13C8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13C8: view

No data available for SIGNOR curated interactions for OR13C8 Gene

Transcripts for OR13C8 Gene

mRNA/cDNA for OR13C8 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C8 Gene

No ASD Table

Relevant External Links for OR13C8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR13C8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR13C8 Gene

Protein differential expression in normal tissues from HIPED for OR13C8 Gene

This gene is overexpressed in CD8 Tcells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR13C8 Gene

Protein tissue co-expression partners for OR13C8 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR13C8 Gene:


SOURCE GeneReport for Unigene cluster for OR13C8 Gene:

genes like me logo Genes that share expression patterns with OR13C8: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR13C8 Gene

Orthologs for OR13C8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C8 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC473003 34
  • 98.96 (n)
OR13C8 35
  • 98 (a)
(Canis familiaris)
Mammalia LOC100685557 34
  • 88.89 (n)
OR13C8 35
  • 86 (a)
(Bos Taurus)
Mammalia OR13C8 34 35
  • 86.73 (n)
(Mus musculus)
Mammalia Or13c25 55 Olfr272 34 16 35
  • 81.97 (n)
(Rattus norvegicus)
Mammalia Olr851 34
  • 80.34 (n)
(Monodelphis domestica)
Mammalia OR13C8 35
  • 73 (a)
Species where no ortholog for OR13C8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C8 Gene

Gene Tree for OR13C8 (if available)
Gene Tree for OR13C8 (if available)

Paralogs for OR13C8 Gene

(453) SIMAP similar genes for OR13C8 Gene using alignment to 1 proteins: Pseudogenes for OR13C8 Gene

genes like me logo Genes that share paralogs with OR13C8: view

Variants for OR13C8 Gene

Sequence variations from dbSNP and Humsavar for OR13C8 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10761039 -- 104,569,053(+) CCAAA(A/T)ACAGA upstream-variant-2KB
rs10991304 -- 104,569,760(+) GATTA(A/C/G)TATGA reference, missense
rs111287340 -- 104,568,531(+) CCGAG(A/G)AGGGC upstream-variant-2KB
rs111890754 -- 104,568,157(+) GATAA(A/G)TTGGC upstream-variant-2KB
rs112082237 -- 104,568,688(+) TGAAC(A/C)CGGGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR13C8 Gene

Variant ID Type Subtype PubMed ID
esv3891705 CNV loss 25118596
esv3891706 CNV gain 25118596
nsv831677 CNV gain 17160897

Variation tolerance for OR13C8 Gene

Residual Variation Intolerance Score: 66.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.42; 54.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR13C8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C8 Gene

Disorders for OR13C8 Gene

Relevant External Links for OR13C8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR13C8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13C8 Gene

Publications for OR13C8 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 64
  4. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R. … Strotmann J. (Genomics 2003) 3 64

Products for OR13C8 Gene

Sources for OR13C8 Gene

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